Last reviewed: May 12, 2026
Last updated: May 12, 2026
Written by:
Jay Hastings
,
CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by:
Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
Two telehealth brands can look interchangeable until you read the price ladder, and Henry Meds publishes one detailed enough to change how you compare it with Hims. This PlexusDx Education Hub review focuses on program structure and cost mechanics, then closes on a genetic factor neither brand measures. Browse all Peptides & GLP-1 education.
Full head-to-head: PlexusDx vs Henry Meds →
Independence note: PlexusDx has no commercial relationship with Hims, Henry Meds, or their parent organizations. This review includes no affiliate links, sponsorship, or referral fees.
Hims and Henry Meds both deliver GLP-1 therapy through telehealth, but Henry publishes a specific per-medication ladder while Hims keeps its numbers on its own site. That contrast makes pricing structure the natural spine of this comparison. Below we cover each program's model, Henry's published rates, the prepay-versus-month-to-month tradeoff, and the inherited variable that sits outside both. Details are current as of the dates noted.
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What Hims is
Hims, under Hims & Hers Health, operates as subscription telehealth. A virtual evaluation leads to a licensed clinician's review and, where appropriate, either an FDA-approved brand GLP-1 or a compounded semaglutide or tirzepatide from a licensed compounding pharmacy. Current program details are published at Hims's official website.
What Henry Meds is
Henry Meds runs telehealth alongside compounded-pharmacy fulfillment. What sets its public presentation apart is a per-medication price ladder with named tiers. The current menu and terms live on Henry Meds's official website, but the published figures below give a concrete sense of how the program structures cost.
How the two models differ on transparency
The structural distinction here is disclosure. Hims presents pricing within its own funnel by product and tier, while Henry advertises a headline number with a caveat: the lowest figure typically requires paying a full year up front. Reading which number is which is the whole game.
Henry Meds' published price ladder
Henry Meds prices its program per medication, and it advertises a low headline number that requires paying 12 months up front, so its month-to-month rate is higher. Here is Henry's ladder as published, each figure labeled (verified July 20, 2026):
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Injectable compounded semaglutide (the flagship): $297/month month-to-month. Prepaid plans lower it, the 6-month plan is $1,482 ($247/month) and the 12-month plan is $2,364 ($197/month). Henry's advertised "$197/month" is that 12-month prepaid-in-full rate, not a month-to-month price.
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Oral (sublingual) semaglutide: $249/month month-to-month, with a $179/month tier.
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Oral tirzepatide: dissolving tablets only, Henry does not offer an injectable tirzepatide as of July 2026. It is sold as a 3-month supply at $1,047 ($891 paid in full); Henry publishes no month-to-month tirzepatide rate.
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Liraglutide (injectable): $179/month month-to-month.
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Phentermine (oral): $149/month.
Henry charges no membership fee and no per-visit consultation fee, the provider evaluation is free, nothing is charged until a prescription is written, and the subscription bundles medication, supplies, shipping, and ongoing care. Its refund policy is not stated. Hims publishes its own pricing on its site; rather than cite a possibly-stale number, verify Hims's current rates directly before any purchase decision. Confirm Henry's figures on Henry Meds's official website.
Prepay versus month-to-month: reading the tradeoff
The lesson generalizes. A low advertised rate can hinge on a long prepaid commitment, which lowers the per-month figure but raises the upfront outlay and the amount at risk if you stop. A month-to-month rate costs more but keeps you flexible. When comparing Hims against Henry, line up the same commitment level and note whether a refund policy is stated.
The pharmacology and its evidence
Both services work within the same drug class. GLP-1 receptor agonists such as semaglutide, liraglutide, and dulaglutide, plus the dual GIP/GLP-1 agonist tirzepatide, act on appetite, satiety, and gastric emptying. The class is well studied: STEP for semaglutide in weight management (New England Journal of Medicine, 2021), SURMOUNT for tirzepatide (NEJM, 2022), and SURMOUNT-OSA for tirzepatide in obstructive sleep apnea (NEJM, 2024). The mechanism follows the compound, not the brand or the payment plan.
The variable no price ladder lists
No pricing tier accounts for the inherited biology a GLP-1 acts on. A variant in MC4R, central to satiety and energy balance, along with FTO, GLP1R (the receptor these compounds target), and TCF7L2 (linked to glucose handling), maps your baseline metabolic terrain. These pathway-level markers do not predict response to a specific compound, but they describe the ground any protocol is built on, whatever you pay for it.
PlexusDx offers semaglutide and tirzepatide through its Weight Management Protocols, available as Semaglutide Injection, Semaglutide Oral, Tirzepatide Injection, and Tirzepatide Oral. Before any protocol, the Precision Peptide Genetic Test reads 14 pathways, 49 peptides, 150+ genetic insights, including FTO, MC4R, and TCF7L2. Test before you invest.
Not affiliated: PlexusDx has no relationship with Hims or Henry Meds and reviewed both independently.
Related reading on PlexusDx: GLP 1 Receptor Agonist, GLP 1 Drugs, GLP 1 Hormone, What Is GLP 1.
Disclaimer: This article is educational. PlexusDx is not affiliated with Hims or Henry Meds and has no commercial relationship with the companies reviewed. PlexusDx offers semaglutide and tirzepatide through its own Weight Management Protocols. The Precision Peptide Genetic Test analyzes how your genes influence peptide-related biological pathways and does not predict response to any specific medication. Consult a qualified healthcare provider before beginning any peptide protocol.
Explore the Weight Management Protocols or start with the Precision Peptide Genetic Test.
Frequently Asked Questions
Why is Henry Meds' advertised price lower than what I would pay monthly?
Henry's advertised "$197/month" for injectable compounded semaglutide is the 12-month prepaid-in-full rate, not a month-to-month price, which is $297/month. Prepaid plans lower the per-month figure but require a larger upfront commitment. Always check which commitment level a headline number reflects before comparing it with another brand.
Does Henry Meds charge membership or consultation fees?
No. Henry charges no membership fee and no per-visit consultation fee; the provider evaluation is free, and nothing is charged until a prescription is written. The subscription bundles medication, supplies, shipping, and ongoing care. Its refund policy is not stated, so confirm that detail on Henry's own site before prepaying.
Does the Precision Peptide Genetic Test factor into pricing?
No. The test is unrelated to any brand's pricing and does not predict drug response. It maps pathway-level variants such as FTO and MC4R, and TCF7L2 that describe your baseline metabolic biology, offering context that applies regardless of which program or price tier you eventually choose.
How does PlexusDx compare with Hims and Henry Meds?
PlexusDx provides semaglutide and tirzepatide through its Weight Management Protocols and adds upstream genetic context via the Precision Peptide Genetic Test, mapping FTO, MC4R. That pathway-level insight is the layer neither Hims nor Henry Meds includes alongside its medication.
More in the Education Hub. Browse all Peptides & GLP-1 education
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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