Henry Meds vs PlexusDx: GLP-1 prices and programs compared
Henry Meds advertises semaglutide as low as $197 a month, but that rate needs a full year paid upfront; its month-to-month price is $297. PlexusDx's injectable semaglutide is one flat $189, month-to-month, with no prepayment. Each wins on a different part of the menu: Henry's oral semaglutide is cheaper and it sells more oral formats, while PlexusDx is lower on injectable semaglutide and is the only one offering injectable tirzepatide.
Is Henry Meds or PlexusDx better?
On injectable semaglutide, PlexusDx is lower — $189 month-to-month against Henry's $297, below Henry's best advertised $197 too. On oral semaglutide, Henry is lower: $249 against our $289.
On injectable semaglutide this isn't close: PlexusDx is $189 month-to-month against Henry's $297, and lower than Henry's best advertised $197 once you count the full year that rate needs prepaid. Henry answers on the other side of the menu, with cheaper oral semaglutide and more oral formats for anyone avoiding needles, while PlexusDx alone offers injectable tirzepatide and an optional genetics add-on.
- You want oral semaglutide. Henry's sublingual tablets are $249/month, about $40 below PlexusDx's $289 oral semaglutide.
- You'd rather not inject and want choice. Henry sells oral semaglutide, oral microdose semaglutide, oral tirzepatide and oral phentermine, a wider oral menu than PlexusDx's.
- You prefer a larger, heavily advertised national brand.
- You want the lower injectable semaglutide price. $189/month, month-to-month, against Henry's $297, and below Henry's best advertised $197 too, with no year of prepayment behind it.
- You want injectable tirzepatide. $289/month month-to-month, down to $249 on a 6-month rate; Henry doesn't offer injectable tirzepatide at all.
- You want a flat price with no lock-in, and a lower rate if you commit. $189 month-to-month, down to $169 on 3 months or $149 on 6; Henry's cheapest semaglutide rate requires paying $2,364 upfront for a year. You can cancel anytime on the monthly plan.
- You want the optional genetics add-on and pharmacist support. The genetics add-on is $298 ($99 for program members), plus a free check-in with a Doctor of Pharmacy. The test doesn't select or predict a medication; your provider decides.
| Criterion | PlexusDx | Henry Meds |
|---|---|---|
| Injectable semaglutide price ($189 vs $297, month-to-month) | 5.0 | 3.0 |
| Oral semaglutide price ($289 vs $249, month-to-month) | 3.5 | 4.5 |
| Injectable tirzepatide availability ($289 month-to-month vs not offered) | 5.0 | 2.0 |
| Oral format breadth for the needle-averse (two oral options vs four) | 3.5 | 4.5 |
| Flat rate with no lock-in ($189 flat beats Henry's best advertised $197, which needs a year prepaid) | 4.5 | 3.0 |
| Lower rates for committing (multi-month savings offered by both) | 4.0 | 4.0 |
| Genetics & pharmacist support (optional add-on + PharmD check-in) | 4.5 | 3.0 |
Our own opinion scoring by the PlexusDx editorial team against each program's July 2026 published pricing and product offerings, not customer ratings. Henry scores higher on oral semaglutide price and oral format breadth. We publish this comparison and are one of its two programs.
How much do Henry Meds and PlexusDx cost per month and per year? (Verified July 2026)
Month-to-month, PlexusDx injectable semaglutide is $189 against Henry's $297 — below even Henry's best advertised $197, which needs a 12-month plan paid in full. On oral semaglutide, Henry is cheaper: $249 against our $289.
Injectable semaglutide is the clean comparison, and PlexusDx wins every tier of it. Oral semaglutide runs the other way — Henry's sublingual tablets are cheaper than our oral, and we're not going to pretend otherwise. On tirzepatide the two programs don't line up: PlexusDx sells an injectable; Henry sells an oral tablet only, as a prepaid 3-month supply with no month-to-month rate.
| Semaglutide injection — by term | PlexusDx | Henry Meds | Difference |
|---|---|---|---|
| Month-to-month | $189/mo, one charge | $297/mo | PlexusDx −$108/mo |
| 3-month rate | $169/mo | No 3-month plan offered | PlexusDx lower |
| 6-month rate | $149/mo | $247/mo — $1,482 for 6 months, paid in full | PlexusDx −$98/mo |
| Henry's best advertised rate | $189/mo month-to-month, no lock-in | $197/mo — $2,364 for 12 months, paid in full | PlexusDx −$8/mo, and no prepay |
| Cost over 12 months | $2,268 month-to-month (no lock-in) · $1,788 at the 6-month rate | $2,364 (12-month plan, paid in full) · $3,564 month-to-month | PlexusDx −$96 to −$576/yr |
Where Henry wins: oral semaglutide
Henry's sublingual (oral) semaglutide tablets are $249/month, month-to-month — about $40 below PlexusDx's oral semaglutide at $289/month. If oral semaglutide is what you want, Henry is the cheaper option. (Henry also lists a $179/month sublingual semaglutide tier.)
PlexusDx's $189 injectable costs less than either, but that's a different format. For a like-for-like oral-to-oral comparison, Henry is lower — and we score it that way above.
| Tirzepatide — availability | PlexusDx | Henry Meds |
|---|---|---|
| Injectable tirzepatide | $289/mo month-to-month (down to $249 on a 6-month rate) | Not offered |
| Oral tirzepatide | $349/mo month-to-month | Oral tablet only — $891 for a 3-month supply, paid in full (list $1,047); no month-to-month rate published |
Henry sells no injectable tirzepatide, so there is no like-for-like month-to-month comparison to draw. Its oral tirzepatide is sold as a prepaid 3-month supply, not a month-to-month plan — so we don't publish a Henry month-to-month oral-tirzepatide figure, because none exists.
Henry Meds figures from Henry's own published program page and its signup flow, captured July 20, 2026. PlexusDx figures are our own published rates. Prices change often — check both sites before deciding.
Injectable semaglutide, $189 a month — no year to prepay
That's below Henry's $297 month-to-month and below its best advertised $197 rate, which needs a full year paid upfront — with no lock-in, and down to $149 on a 6-month rate. A licensed provider reviews your intake before anything is prescribed.
How do PlexusDx and Henry Meds compare, feature by feature?
Both are cash-pay compounded-GLP-1 programs with no membership fee. PlexusDx bills a flat month-to-month rate and undercuts Henry on injectable semaglutide; Henry offers cheaper oral semaglutide and a broader oral lineup.
| Feature | PlexusDx | Henry Meds |
|---|---|---|
| Injectable semaglutide, month-to-month | $189/mo | $297/mo |
| Oral semaglutide, month-to-month | $289/mo | $249/mo |
| Injectable tirzepatide | Yes — $289/mo | Not offered — oral tirzepatide only |
| No-injection lineup | Oral semaglutide & tirzepatide | Four oral products, incl. phentermine |
| Flat rate with no prepay required | Yes — $189/$289 with no upfront commitment | Best rate ($197/mo) requires a 12-month plan paid in full |
| Required membership fee | None | None |
| Charged before provider approval | A licensed provider reviews your intake first | No — $0 until prescribed |
| Optional genetics add-on | Yes — $298, or $99 for members | No |
| Free named-pharmacist check-in | Yes — Dr. Jayden Lee, PharmD | No |
Compiled from Henry Meds' own published program page and its signup flow, captured July 2026, alongside PlexusDx's published rates. Month-to-month rates shown unless noted; Henry's $197/mo requires a 12-month plan paid in full.
When is Henry Meds the better choice?
Henry is the better pick if you want to avoid injections, or want oral semaglutide at a lower price — its oral lineup is broader and its oral semaglutide undercuts ours.
- Its oral semaglutide is cheaper. Henry's sublingual semaglutide tablets are $249/month month-to-month, versus PlexusDx's oral semaglutide at $289 — about $40 less each month.
- Its no-injection lineup is broader. Henry publishes four oral products — semaglutide, microdose semaglutide, tirzepatide, and phentermine — so the needle-averse have more ways to start.
- It's a larger, longer-established brand. Henry Meds (Adonis Health Inc.) is one of the better-known compounded-GLP-1 telehealth names.
- It charges $0 at signup — its screens state you "will only be charged if you are prescribed medication."
When is PlexusDx the better choice?
PlexusDx is the better pick for injectable semaglutide at a far lower price, injectable tirzepatide Henry doesn't offer, a flat month-to-month rate with no prepay, plus genetics and pharmacist support.
- Injectable semaglutide costs far less. $189/month month-to-month versus Henry's $297 — $108 less each month, and below Henry's best advertised rate ($197, which needs $2,364 paid upfront for a year).
- Injectable tirzepatide Henry doesn't offer. PlexusDx offers it at $289/month month-to-month; Henry sells tirzepatide as an oral tablet only.
- Flat month-to-month, no lock-in. Your rate doesn't require prepaying a year to reach; committing to 3 or 6 months lowers it further ($149/$249 sema/tirz at 6 months).
- Genetics and a named pharmacist. An optional Precision Peptide Genetic Test ($298, or $99 for program members) and a free check-in with Dr. Jayden Lee, PharmD. It does not select or predict a medication; your provider decides.
Which formats does each program offer?
PlexusDx leads on injectables — injectable tirzepatide and a combination protocol Henry doesn't sell. Henry leads on oral breadth — four oral products, including a cheaper oral semaglutide.
- Henry serves the needle-averse well. Its four oral products — semaglutide, microdose semaglutide, tirzepatide, and phentermine — give more no-injection choices than PlexusDx's two.
- On oral semaglutide, Henry is cheaper. Henry $249/month versus PlexusDx $289 — an honest $40 premium on our side.
- PlexusDx leads on injectables. Injectable semaglutide $189/month undercuts Henry's $297, and injectable tirzepatide ($289) isn't something Henry offers at all.
Henry Meds formats — published and advertised pricing, labelled
- Injectable compounded semaglutide — $297/mo month-to-month (best advertised $197/mo requires a 12-month plan paid in full)
- Injectable microdose semaglutide — advertised $149/mo (12-month plan paid in full)
- Oral (sublingual) semaglutide — $249/mo month-to-month · a $179/mo tablets-or-drops tier
- Oral microdose semaglutide — advertised $99/mo (3-month plan paid in full)
- Oral tirzepatide — $1,047 for a 3-month supply ($891 paid in full) · no month-to-month rate published
- Injectable liraglutide — $179/mo month-to-month
- Oral phentermine — $149/mo month-to-month
PlexusDx GLP-1 formats — published pricing, month-to-month first
- Semaglutide injection — $189/mo month-to-month · $169 (3-mo) · $149 (6-mo)
- Tirzepatide injection — $289/mo month-to-month · $269 (3-mo) · $249 (6-mo)
- Oral semaglutide — $289/mo month-to-month · $269 (3-mo) · $249 (6-mo) — no-injection format, priced above Henry's $249 oral
- Oral tirzepatide — $349/mo month-to-month · $299 (3-mo) · $279 (6-mo)
- GLP-Squared combination protocol — $289/mo month-to-month · $249 (3-mo)
- Microdose GLP-1 — $129/mo flat, a lower-cost entry point
How does Henry Meds pricing work?
Henry charges one subscription covering medication, supplies, shipping and care, with no membership fee. Its flagship injectable semaglutide is $297/month month-to-month, or less per month if you prepay 6 or 12 months.
Henry states its cancellation terms in two places, and they sit in tension. We quote both in Henry's own words:
- Its Terms of Service, agreed at signup, say you "commit to paying the subscription fee for the full contract term if prescribed medication, regardless of usage."
- Its cancellation policy says you "can cancel at any time… If you're on a multi-month plan, you may be required to pay out the rest of your balance unless… medical" reasons determined by a healthcare provider.
Henry charges $0 until a provider prescribes medication. Its refund policy is not stated on the pages we reviewed.
How does PlexusDx pricing work?
PlexusDx charges one flat, all-inclusive rate per medication, the same at every dose — injectable semaglutide $189/month and tirzepatide $289/month month-to-month, dropping to $149/$249 on a 6-month plan.
On injectable semaglutide, PlexusDx is lower at every comparable point — and its month-to-month rate beats Henry's deepest prepaid rate with no lock-in.
- Month-to-month: $189 (PlexusDx) vs $297 (Henry) — $108 less each month.
- One year, no lock-in: $2,268 month-to-month at PlexusDx vs Henry's $2,364 for 12 months paid upfront — and $189 is below Henry's best advertised $197/mo.
- On oral semaglutide, Henry is cheaper — $249 vs our $289. We concede that tier.
Does either program look at your biology or include pharmacist support?
Neither program includes a DNA-based test as part of its GLP-1 program. PlexusDx offers one as an optional add-on — $298, or $99 for program members.
The optional Precision Peptide Genetic Test gives you and your licensed provider added clarity on how your body is wired. The idea is simple: know your biology, don't guess at it.
- What it reads: Weight-management insights, drawn from a panel of 150+ genetic insights across 14 pathways.
- Price: $298 — program members receive a $199 discount code about 10 days after their order, bringing it to $99.
- What it isn't: it does not select or predict a medication; your provider decides — and it won't predict how you'll respond. It's context, not a prescription.
Every PlexusDx prescription includes a free 15-minute check-in with our Medical Director and Doctor of Pharmacy — by video or phone — to talk through medication questions, side effects, and how your protocol is going. It's education and support; your licensed provider still makes every prescribing decision.
How did we verify these prices?
We read Henry's own published program page and ran its signup flow to the order summary on July 20, 2026. Henry charges $0 until a provider prescribes, so no charge was confirmed.
Method. We read Henry's published program page and ran its guided weight-management signup to the order summary. On the subscription screen the month-to-month plan for injectable compounded semaglutide was pre-selected at $297/month, and the order summary listed "Recurring monthly cost $297/mo" with "$0 due today." That $297 matches Henry's own published program table exactly. We used only Henry's own pages — no aggregator or third-party review site.
What we could not confirm. Henry charges nothing until a provider prescribes, so we never reached a billed transaction. The $297 is Henry's published month-to-month rate, not an amount we were charged. Henry also advertises $197/month; that rate requires a 12-month plan paid upfront in full — $2,364 in a single charge. Both figures are real, and we label each so neither stands alone bare.
A note on who wrote this. PlexusDx publishes this page and is one of the two programs compared, so we are not a neutral party. That's why we used Henry's own program page and signup flow as the only source for its figures, and why we state plainly where Henry beats us. Category pricing changes often; check both sites before you decide.
- Henry's oral semaglutide is cheaper. Its sublingual semaglutide tablets run $249/month, below our oral semaglutide at $289.
- Henry serves the needle-averse well. It offers a broader by-mouth lineup — oral semaglutide, oral microdose semaglutide, oral tirzepatide, and oral phentermine.
- Henry charges nothing until a provider prescribes. Its provider evaluation is free, and it bills only if you're prescribed.
See your PlexusDx price — one flat rate, no 12-month prepay
One published month-to-month price covering the provider consult, prescription, medication and shipping — no separate membership, no year paid upfront — with 3- and 6-month rates if you want them. Injectable semaglutide $189/mo, injectable tirzepatide $289/mo. A licensed provider reviews your intake before anything is prescribed.
Start your intakeFrequently Asked Questions
What is compounded GLP-1?
Compounded GLP-1 medications are semaglutide or tirzepatide prepared for an individual patient by a state-licensed 503A compounding pharmacy on a valid prescription. They are not FDA-approved. Both Henry Meds and PlexusDx operate in this category.
- Not FDA-reviewed. Compounded medications are not reviewed by the FDA for safety, quality, or effectiveness.
- The approved versions. Only Novo Nordisk (semaglutide) and Lilly (tirzepatide) make FDA-approved branded products.
Are compounded GLP-1 medications FDA-approved?
No — compounded medications are not FDA-approved and are not reviewed by the FDA for safety, quality, or effectiveness. They are prepared by a state-licensed 503A pharmacy for an individual patient on a valid prescription.
- Semaglutide. Novo Nordisk is the only U.S. company with FDA-approved semaglutide (Wegovy®, Ozempic®, Rybelsus®).
- Tirzepatide. Lilly is the only U.S. company with FDA-approved tirzepatide (Zepbound®, Mounjaro®).
Is PlexusDx cheaper than Henry Meds?
It depends on the medication: PlexusDx is cheaper on injectable semaglutide ($189 vs $297 month-to-month), while Henry Meds is cheaper on oral semaglutide ($249 vs our $289). PlexusDx also offers injectable tirzepatide, which Henry does not.
- Injectable semaglutide — PlexusDx wins clearly. $189/month versus Henry's $297, and below Henry's best advertised rate ($197), which requires $2,364 paid upfront — with no lock-in.
- Oral semaglutide — Henry wins. Its sublingual semaglutide is $249/month against our $289; if you prefer an oral option, that's a genuine Henry advantage.
- PlexusDx's 3- and 6-month injectable rates — $169/$149 semaglutide and $269/$249 tirzepatide — widen the gap further.
How much does Henry Meds cost?
Henry publishes $297/month, month-to-month, for injectable compounded semaglutide — the plan its subscription screen pre-selected when we ran its signup on July 20, 2026. Its advertised $197/month requires a 12-month plan paid upfront in full ($2,364).
- Prepay tiers. Henry also lists a 6-month plan at $1,482 ($247/month) and a 12-month plan at $2,364 ($197/month).
- Charged only if prescribed. Henry's order summary showed "$0 due today"; it bills only after a provider prescribes.
- Other products differ. Oral semaglutide is $249/month; oral tirzepatide is sold as a 3-month supply ($1,047, or $891 if paid in full).
Does Henry Meds sell injectable tirzepatide?
No — Henry Meds offers tirzepatide only as an oral dissolving tablet, not as an injection. PlexusDx offers injectable tirzepatide at $289/month month-to-month; this is a product-availability difference, not just a price one.
- Henry's injectables are semaglutide and liraglutide only; its tirzepatide, oral semaglutide, oral microdose semaglutide, and phentermine are taken by mouth.
- Henry's oral tirzepatide is sold as a 3-month supply ($1,047, or $891 if paid in full), with no published month-to-month rate.
Does Henry Meds charge a membership fee?
No — we found no membership, admin, or platform fee in Henry's signup flow or on its published program page. Its monthly price includes medication, shipping, and provider access, and PlexusDx works the same way — one flat price, no separate membership.
- Henry's own words: its subscription "includes the cost of medication, shipping, and access to healthcare providers."
Can I cancel anytime, or am I locked into a contract?
It depends on the plan you choose, and Henry's own terms sit in tension on this point. PlexusDx's month-to-month plan has no contract; you can stop between refills.
- Henry's Terms of Service ask patients to "commit to paying the subscription fee for the full contract term if prescribed medication, regardless of usage."
- Henry's FAQ says you "can cancel at any time," adding that on a multi-month plan you "may be required to pay out the rest of your balance unless you're unable to continue for medical-related reasons." We quote both and leave the interpretation to you.
- PlexusDx's 3- and 6-month rates trade a longer commitment for a lower price; its month-to-month plan has none.
Does the price change as my dose increases?
No — PlexusDx charges the same price at every dose level. Henry states its price 'varies by treatment plan and dosing… starts at $179/month,' but publishes no dose surcharge, and its flagship injectable semaglutide is one price across both dose options it lists.
- We report only what's published. Henry lists no surcharge schedule, so we make no claim about how its pricing changes at higher doses.
Which states is PlexusDx available in?
PlexusDx is available in most U.S. states where telehealth prescribing of these medications is permitted. You'll confirm whether your state is covered during intake. Henry Meds operates on a similar state-by-state basis.
Is shipping included?
Yes — PlexusDx includes direct-to-door shipping in its monthly price, with no separate shipping fee. Your medication ships from a state-licensed 503A pharmacy after your provider approves it. Henry Meds also includes shipping.
What are the common side effects, and what support is there?
The most common GLP-1 side effects are gastrointestinal — nausea and digestive changes — usually most noticeable when starting or increasing a dose. Your provider titrates your dose to manage tolerability. This page is not medical advice.
- Every PlexusDx prescription includes a free 15-minute check-in with Dr. Jayden Lee, PharmD, for side-effect and medication questions.
- Discuss any symptoms with your provider.
What does the PlexusDx genetics test do?
It analyzes how your genes influence weight-management-related biological pathways, to inform your conversation with your provider. It does not select or predict a medication; your provider decides.
- An optional add-on — $298, or $99 for program members. Neither program includes a DNA-based test as part of its GLP-1 program.
- It does not recommend, prescribe, or determine which medication you should use, and it does not predict your response to any specific drug.
How much does the PlexusDx program cost per year?
Month-to-month, PlexusDx works out to about $2,268/year for injectable semaglutide and $3,468 for injectable tirzepatide, with no year paid upfront. On a 6-month rate it's about $1,788 and $2,988. Henry's 12-month injectable-semaglutide plan is $2,364, paid upfront in full.
PlexusDx tells you about your biology. It does not tell you what to put in your body.