Henry Meds vs Low-Cost GLP-1 Providers: Price and Service Compared

Last reviewed: September 18, 2026 Last updated: September 18, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

For injectable compounded semaglutide, PlexusDx costs $189/month on month-to-month terms and $149/month on a six-month plan; Henry Meds charges $297/month month-to-month and $247/month on a six-month plan. Over 12 months, PlexusDx's month-to-month cost is $2,268 versus Henry Meds' $3,564—a $1,296 difference (our calculation, September 2026). Henry Meds offers a 12-month prepaid plan at $197/month prepaid equivalent ($2,364 paid upfront) that narrows the gap but still costs $96 more than PlexusDx's six-month plan rate annualized. For oral semaglutide, Henry Meds costs $249/month versus PlexusDx's $289/month—a $480/year advantage for Henry (our calculation). Both programs are all-inclusive with no separate membership fees. Injectable semaglutide is the like-for-like center of the comparison; oral formats and tirzepatide options differ between the two.

At-a-glance comparison

All figures verified July–September 2026. PlexusDx pricing captured July 17–23, 2026; Henry Meds pricing captured July 20 and September 4, 2026.

Injectable semaglutide: like-for-like pricing normalized over 12 months

Injectable compounded semaglutide is the most direct head-to-head comparison. Both providers offer month-to-month plans and six-month prepaid plans; Henry Meds also offers a 12-month prepaid option.

Month-to-month plans over 12 months

• PlexusDx: 12 × $189 = $2,268/year (our calculation)
• Henry Meds: 12 × $297 = $3,564/year (our calculation)
• Difference: $1,296/year lower with PlexusDx (our calculation)

PlexusDx wins decisively on month-to-month injectable semaglutide.

Six-month plans over 12 months (two cycles)

• PlexusDx: 2 × $894 = $1,788/year (our calculation)
• Henry Meds: 2 × $1,482 = $2,964/year (our calculation)
• Difference: $1,176/year lower with PlexusDx (our calculation)

The six-month plan advantage remains material, though slightly narrowed from the month-to-month gap.

Henry Meds' 12-month prepaid plan

Henry Meds' 12-month plan costs $2,364 paid upfront for the full year—a prepaid equivalent of $197/month (our calculation). This is Henry's lowest per-month rate for injectable semaglutide. When annualized, it costs $96 more than PlexusDx's six-month plan rate over 12 months (our calculation). The 12-month plan requires prepaying the entire year; early cancellation may require paying the remaining balance unless a medical exception is approved by a provider, according to Henry Meds' cancellation policy (captured September 18, 2026).

PlexusDx does not offer a 12-month plan. The six-month plan ($149/month prepaid, $894 upfront per cycle) remains PlexusDx's longest commitment option.

Oral semaglutide: Henry Meds wins on price

For oral semaglutide, Henry Meds offers sublingual tablets at $249/month on month-to-month terms (captured September 4, 2026). PlexusDx offers oral semaglutide capsules at $289/month (captured July 17–23, 2026). Over 12 months:

• Henry Meds sublingual: 12 × $249 = $2,988/year (our calculation)
• PlexusDx oral capsules: 12 × $289 = $3,468/year (our calculation)
• Difference: $480/year lower with Henry Meds (our calculation)

Henry Meds also offers six-month and 12-month prepaid plans for oral semaglutide. The six-month plan costs $179/month prepaid equivalent (either $1,074 or $1,014 paid upfront—evidence shows two figures; confirm at checkout) and the 12-month plan costs $149/month prepaid equivalent ($1,788 paid upfront for the full year), according to pricing captured September 4, 2026. These prepaid rates bring Henry's oral semaglutide cost substantially below PlexusDx's oral option.

Tirzepatide: different formats, no injectable head-to-head

PlexusDx offers both injectable tirzepatide ($289/month month-to-month, $249/month on a six-month plan) and oral tirzepatide capsules ($289/month month-to-month). Henry Meds offers only oral tirzepatide—an oral dissolving tablet sold in a three-month supply for $891 upfront, or $297/month prepaid equivalent (our calculation, captured September 4, 2026). Henry Meds does not offer injectable tirzepatide.

There is no like-for-like injectable tirzepatide comparison. For oral tirzepatide, the formats differ (PlexusDx capsule vs. Henry dissolving tablet) and the pricing is similar ($297 vs. $289 per month). Evidence for Henry's oral tirzepatide contains a supply-duration conflict—one source note states "delivered every 60 days for 6 months," but the pricing reflects a three-month supply. We recommend confirming supply terms at checkout.

Microdose GLP-1 and other medication options

PlexusDx offers a microdose GLP-1 protocol—compounded semaglutide injection at a lower dose—for $129/month (captured July 17–23, 2026). This is PlexusDx's lowest-cost option. Henry Meds states that GLP-1 treatment is advertised from an introductory rate of $179/month on its microdose page (captured September 18, 2026), though it is unclear whether this figure reflects the microdose option, the premium semaglutide tablet product, or the liraglutide injection, all of which are priced at $179/month month-to-month in various product lines (captured September 4, 2026). For microdose GLP-1 specifically, PlexusDx's $129/month rate is $50/month lower than the $179 introductory floor advertised by Henry Meds (our calculation).

Henry Meds also offers compounded liraglutide injection at $179/month month-to-month (captured September 4, 2026). PlexusDx does not offer liraglutide.

Service model and what is included

Both programs are all-inclusive telehealth services with no separate membership fees. The monthly price covers the online provider visit, prescription, medication, shipping, and supplies. Both work with 503A compounding pharmacies. Henry Meds also works with outsourcing facilities, according to its website (captured September 18, 2026).

Henry Meds states that most patients receive medication within 8–10 business days after the provider visit. Injectable refills ship every 45 days; oral tablets every 90 days. California fulfillment may take longer due to additional testing requirements (captured September 18, 2026). PlexusDx offers a free check-in with a Doctor of Pharmacy as part of its program (captured July 20, 2026).

Henry Meds treats patients ages 18–70 for GLP-1 therapy (captured September 18, 2026). PlexusDx eligibility criteria were not specified in the evidence reviewed.

Review ratings and customer feedback

PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). Henry Meds holds a 4.4-star rating on Trustpilot (captured September 18, 2026). Both providers show strong customer satisfaction on the platform. We did not review individual customer feedback themes for this comparison.

Cancellation and commitment terms

PlexusDx month-to-month plans can be canceled anytime (captured July 20, 2026). Henry Meds month-to-month plans can also be canceled anytime via the patient portal, email (ask@henrymeds.com), or phone (909-787-2342). For Henry Meds' multi-month prepaid plans, cancellation may require paying the remaining balance unless a medical-related cancellation is approved by a provider (captured September 18, 2026). Confirm prepaid plan cancellation terms at enrollment.

Choose PlexusDx if…

• You want the lowest month-to-month injectable semaglutide rate with no prepay commitment.
• You prefer a six-month plan and want the lowest annualized cost over 12 months.
• You want injectable tirzepatide (Henry Meds does not offer it).
• You are considering microdose GLP-1 and want the lowest available monthly rate ($129 vs. $179).
• You value a free check-in with a Doctor of Pharmacy as part of the program.

Choose Henry Meds if…

• You want oral semaglutide and prefer Henry's sublingual format at $249/month over PlexusDx's capsule at $289/month.
• You are willing to prepay 12 months upfront for injectable semaglutide and want the lowest possible per-month prepaid equivalent rate ($197/month, $2,364 paid upfront).
• You want compounded liraglutide (PlexusDx does not offer it).
• You prefer a provider with a slightly higher Trustpilot rating (4.4 vs. 4.3 stars, though both are strong).

Methodology and freshness

All pricing and service facts in this comparison were gathered from publicly available provider websites, product pages, and FAQ sections. PlexusDx pricing was captured July 17–23, 2026. Henry Meds pricing was captured July 20 and September 4, 2026. Review ratings were captured September 9, 2026 (PlexusDx) and September 18, 2026 (Henry Meds). All 12-month cost totals and per-month prepaid equivalents are our calculation, derived from the verified figures published by each provider. We recommend confirming current pricing, eligibility, and cancellation terms at checkout, as telehealth pricing and policies may change.

Frequently Asked Questions

Does PlexusDx or Henry Meds charge a separate membership fee?

Neither provider charges a separate membership fee. Both programs are all-inclusive: the monthly medication price covers the provider visit, prescription, medication, shipping, and supplies.

Can I get injectable tirzepatide from Henry Meds?

No. Henry Meds offers only oral tirzepatide as a dissolving tablet. PlexusDx offers both injectable tirzepatide ($289/month month-to-month, $249/month on a six-month plan) and oral tirzepatide capsules ($289/month month-to-month).

What is the real 12-month cost difference for injectable semaglutide on month-to-month plans?

PlexusDx costs $2,268 over 12 months at $189/month (our calculation). Henry Meds costs $3,564 over 12 months at $297/month (our calculation). The difference is $1,296/year in PlexusDx's favor (our calculation).

Does Henry Meds' 12-month plan beat PlexusDx's six-month plan?

Henry's 12-month plan costs $2,364 paid upfront for the full year, or $197/month prepaid equivalent (our calculation). PlexusDx's six-month plan costs $1,788/year over two cycles, or $149/month prepaid (our calculation). PlexusDx's six-month rate is still $96/year lower over 12 months (our calculation). Henry's plan requires a full-year prepay; PlexusDx's requires two six-month prepays.

Are these medications FDA-approved?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies. Henry Meds works with 503A compounding pharmacies and outsourcing facilities.

Sources

• PlexusDx product pricing and program details (plexusdx.com, accessed July 17–23, 2026)
• Henry Meds product pricing and program details (henrymeds.com, accessed July 20 and September 4, 2026)
• Henry Meds FAQ and cancellation policy (henrymeds.com, accessed September 18, 2026)
• PlexusDx Trustpilot profile (trustpilot.com/review/plexusdx.com, accessed September 9, 2026)
• Henry Meds Trustpilot profile (accessed September 18, 2026)

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.