Last reviewed: September 5, 2026 Last updated: September 5, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Henry Meds and Eden both offer compounded semaglutide and tirzepatide in both injectable and oral forms, but the economics differ in structure and scale. Henry Meds posts straightforward per-month rates and unlocks prepaid discounts across 6-month and 12-month commitments; Eden separates medication and membership into two recurring charges, with a discounted first month that raises the effective cost thereafter. On a month-to-month basis, Henry Meds charges $297 for injectable semaglutide, Eden $198 ongoing after a $138 first month; Henry Meds oral sublingual semaglutide is $249 month-to-month, Eden semaglutide (route varies) $198 ongoing. For injectable tirzepatide, Henry Meds does not offer it; Eden charges $298 ongoing after a $238 first month. Oral tirzepatide at Henry Meds appears only as a 3-month prepaid bundle at $297/month equivalent, while Eden charges the same $298 ongoing monthly rate for tirzepatide regardless of route. PlexusDx enters the comparison at $189 month-to-month for injectable semaglutide, dropping to $149 on a 6-month prepaid plan, and $289 month-to-month for injectable tirzepatide, dropping to $249 on a 6-month prepaid plan—no separate membership, one charge, cancel anytime. Which option delivers better value depends on your preferred medication, your willingness to prepay, and whether a two-part billing model or all-inclusive single charge fits your budget planning.

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At-a-glance comparison

Henry Meds Eden PlexusDx
Semaglutide injection MTM $297/month $198/month ongoing
($138 first month)
$189/month
Semaglutide injection prepaid 6-mo: $247/month ($1,482 upfront)
12-mo: $197/month ($2,364 upfront)
Not offered 3-mo: $169/month ($507 upfront)
6-mo: $149/month ($894 upfront)
Tirzepatide injection MTM Not offered $298/month ongoing
($238 first month)
$289/month
Tirzepatide injection prepaid Not offered Not offered 3-mo: $269/month ($807 upfront)
6-mo: $249/month ($1,494 upfront)
Oral semaglutide MTM Sublingual: $249/month
Premium tablets/drops: $179/month
$198/month ongoing
($138 first month)
(route varies)
$289/month
Oral tirzepatide MTM No MTM rate published;
3-mo prepaid $297/month
$298/month ongoing
($238 first month)
(route varies)
$349/month
Membership or recurring fee None $99/month required
($39 first month)
None
What's included Medication, provider visits, supplies, shipping Medication + membership (two charges) Medication, provider visit, shipping
Trustpilot rating 4.4 stars, ~13,000 reviews 4.5 stars, ~5,000 reviews 4.2 stars, 76% five-star, 81% four-star or higher

Henry Meds and Eden pricing captured July–September 2026; PlexusDx pricing current as of September 5, 2026.

Month-to-month pricing: single charge vs. dual-line billing

Henry Meds publishes a single all-inclusive monthly rate for each formulation: $297 for injectable semaglutide, $249 for oral sublingual semaglutide, $179 for premium oral semaglutide tablets or drops, and $179 for liraglutide injection. No separate membership fee appears; the posted figure covers medication, provider visits, supplies, and shipping. Cancellation on month-to-month plans is unrestricted—account portal, email to ask@henrymeds.com, or phone to 909-787-2342.

Eden separates medication and membership into two recurring charges. Injectable or oral semaglutide medication costs $99/month, and the required membership adds $99/month, for a combined $198/month ongoing. The membership is discounted to $39 for the first month, so the first month totals $138. Injectable or oral tirzepatide medication costs $199/month, membership remains $99/month after the first-month $39 introductory rate, for a combined $298/month ongoing and $238 in the first month. Eden's checkout states "card won't be charged until plan is medically approved within 24 hours" and that completing purchase means "agree to a monthly membership" billed at $99/month. Cancellation is advertised as "cancel anytime," though the mechanism and any membership-hold options are not detailed in the captured evidence.

PlexusDx charges $189/month for injectable semaglutide month-to-month, $289/month for injectable tirzepatide, and $289/month for oral semaglutide—each figure all-inclusive, no membership, cancel anytime. The PlexusDx model matches Henry Meds in structure (one charge) but undercuts Henry Meds on injectable semaglutide by $108/month and Eden's ongoing rate by $9/month; for tirzepatide, PlexusDx sits $9 below Eden's ongoing rate.

12-month cost, month-to-month billing (our calculation)

Injectable semaglutide:

  • Henry Meds: 12 × $297 = $3,564
  • Eden: introductory first-month $138 + eleven months × $198 = $2,316 first year; ongoing years $2,376
  • PlexusDx: 12 × $189 = $2,268

Tirzepatide injection:

  • Henry Meds: not offered
  • Eden: introductory first-month $238 + eleven months × $298 = $3,516 first year; ongoing years $3,576
  • PlexusDx: 12 × $289 = $3,468

Eden's first-year semaglutide cost is lower than Henry Meds month-to-month and sits between PlexusDx month-to-month and Henry Meds; Eden's second-year cost rises to $2,376. For tirzepatide, PlexusDx month-to-month is $48 less than Eden's first year and $108 less than Eden's ongoing years.

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Prepaid plans and annual commitment discounts

Henry Meds offers 6-month and 12-month prepaid plans across most formulations. Injectable semaglutide drops from $297 month-to-month to a 6-month prepaid rate of $247/month ($1,482 upfront) or a 12-month prepaid rate of $197/month ($2,364 upfront, verified July 20 and September 4, 2026). Over 12 months the 12-month plan totals $2,364, saving $1,200 against month-to-month. Oral sublingual semaglutide drops from $249 to a 6-month prepaid rate of $169/month ($1,014 upfront) or a 12-month prepaid rate of $149/month ($1,788 upfront, verified July 20 and September 4, 2026); the 12-month commitment saves $1,200 over the year. Premium oral semaglutide (tablets or drops) at $179 month-to-month falls to a 12-month prepaid rate of $149/month ($1,788 upfront, verified September 4, 2026), saving $360 annually. Liraglutide injection drops from $179 to a 12-month prepaid rate of $119/month ($1,428 upfront, verified September 4, 2026). Henry Meds' legal page states that multi-month plans "may be required to pay out the rest of your balance unless you're unable to continue for medical-related reasons as determined by a healthcare provider."

Oral tirzepatide at Henry Meds appears only as a 3-month prepaid supply at $297/month equivalent ($891 upfront, verified September 4, 2026), though the legal-page copy contains internal inconsistencies—the heading describes a 3-month supply, while body text states "delivered every 60 days for 6 months." No month-to-month rate for oral tirzepatide is published in the captured evidence.

Eden does not offer multi-month prepaid plans in the captured evidence; all billing is monthly.

PlexusDx offers 3-month and 6-month prepaid tiers. Injectable semaglutide is $169/month on a 3-month prepaid plan ($507 upfront) and $149/month on a 6-month prepaid plan ($894 upfront). Over 12 months the 6-month plan—two cycles of $894—costs $1,788, matching Henry Meds' 12-month oral sublingual rate and undercutting Henry Meds' 12-month injectable rate by $576. Injectable tirzepatide is $269/month on a 3-month prepaid plan and $249/month on a 6-month prepaid plan ($1,494 upfront); two cycles total $2,988 annually. Oral semaglutide at PlexusDx is $269/month on a 3-month prepaid plan and $249/month on a 6-month prepaid plan.

12-month prepaid cost comparison (our calculation)

Injectable semaglutide:

  • Henry Meds 12-month prepaid: $2,364
  • Eden: not offered; MTM introductory first year $2,316, ongoing years $2,376
  • PlexusDx 6-month prepaid (two cycles): $1,788

Oral semaglutide sublingual/tablets:

  • Henry Meds sublingual 12-month prepaid: $1,788
  • Henry Meds premium oral 12-month prepaid: $1,788
  • Eden: not offered; MTM introductory first year $2,316, ongoing years $2,376
  • PlexusDx oral 6-month prepaid (two cycles): $2,988

Henry Meds' 12-month oral semaglutide prepaid plans deliver the lowest annual cost in this comparison at $1,788; PlexusDx injectable semaglutide 6-month prepaid matches that figure. For injectable semaglutide with a 12-month lens, PlexusDx 6-month prepaid saves $576 against Henry Meds' 12-month commitment.

Injectable tirzepatide: Eden only, among these three

Henry Meds does not offer injectable tirzepatide in the captured evidence; the medication list includes compounded oral tirzepatide, injectable semaglutide, oral semaglutide, liraglutide injection, and microdose GLP-1 injection, but injectable tirzepatide is absent. Eden offers tirzepatide at $199/month medication plus $99/month membership ($298 ongoing after a $238 first-month rate, verified July 19 and September 4, 2026), and the checkout indicates that "injectable and oral availability varies" and is "clinician-dependent." This means a patient seeking injectable tirzepatide specifically should confirm route availability with Eden's provider during intake, and the same route-variance language applies to Eden's semaglutide offerings.

PlexusDx provides injectable tirzepatide at $289 month-to-month, $269 on a 3-month prepaid plan, and $249 on a 6-month prepaid plan—$9 below Eden's ongoing month-to-month rate, and $588 less over 12 months when comparing PlexusDx 6-month prepaid (two cycles, $2,988) to Eden month-to-month (ongoing years $3,576, introductory first year $3,516).

Oral GLP-1 formulations: sublingual, tablets, drops, capsules

Henry Meds markets three distinct oral semaglutide offerings: sublingual tablets at $249 month-to-month, premium oral tablets or drops at $179 month-to-month, and a 3-month prepaid oral semaglutide bundle at $179/month equivalent ($537 upfront, though the legal page also lists a "$747 standard total" and contains a copy error naming tirzepatide, verified September 4, 2026). The sublingual and premium lines each offer 6-month and 12-month prepaid discounts, converging at $149/month for a 12-month commitment. Oral tirzepatide is listed as a 3-month prepaid option at $297/month equivalent.

Eden does not distinguish formulation type in its published pricing; the $99/month medication rate applies to semaglutide (injectable or oral) and the $199/month rate to tirzepatide (injectable or oral), with the legal language stating "route/availability clinician-dependent." This structure offers flexibility if a patient is indifferent to route, but it also introduces uncertainty—confirmation of the desired route happens during the provider evaluation, not at checkout.

PlexusDx oral semaglutide is $289 month-to-month, $269 on a 3-month prepaid plan, and $249 on a 6-month prepaid plan; oral tirzepatide is $349 month-to-month, $299 on a 3-month prepaid plan, and $279 on a 6-month prepaid plan. Henry Meds' oral options undercut PlexusDx on both month-to-month and prepaid tiers, and Eden's ongoing $198 for oral semaglutide (when available) is also lower than PlexusDx oral. For patients prioritizing oral delivery, Henry Meds' pricing structure is the most competitive in this set, particularly on longer commitments.

Shipping, fulfillment, and pharmacy networks

Henry Meds states that most patients receive medication within 8–10 business days after provider approval, with ongoing shipments every 45 days for injectables and every 90 days for oral tablets. California residents "may experience increased fulfillment time due to additional compound testing requirements." Henry Meds exclusively works with licensed compounding pharmacies in the United States and includes the required disclosure that compounded medications "do not undergo pre-market review or an FDA-approval process. They may differ in efficacy, safety, risk, and side-effect profiles from commercially available or FDA-approved drugs."

Eden's fulfillment timeline and pharmacy network details are not captured in the provided evidence. The checkout language confirms that the card will not be charged until the plan is medically approved within 24 hours, but shipping and partner-pharmacy specifics are not documented here.

PlexusDx works with licensed 503A compounding pharmacies and ships medication after provider approval. Typical fulfillment is five to seven business days; ongoing injectable shipments align with the patient's dosing schedule, and oral capsule refills ship on a monthly cycle.

Service quality and reported user experience

Henry Meds holds a 4.4-star rating on Trustpilot across approximately 13,000 reviews, captured September 4, 2026. This volume of feedback and the aggregate rating place Henry Meds among the higher-rated telehealth weight-management providers in public view. The research pass included a Reddit search but did not isolate a dominant negative theme; the combination of rating and review count suggests broad user satisfaction, though individual reports of delays, communication gaps, or dosing adjustments will exist in any large sample.

Eden holds a 4.5-star rating on Trustpilot across approximately 5,000 reviews, captured the same date. One captured 1-star Trustpilot review reported an 11-day order delay and repeated requests for records Eden had previously issued; this is an individual allegation and should be read as one data point rather than a verified systemic pattern. The higher star average and smaller review pool mean fewer public complaints in absolute terms, but also less statistical depth than Henry Meds' larger sample.

PlexusDx holds a 4.2-star rating on Trustpilot, with 76% of reviews at five stars and 81% at four stars or higher, captured September 4, 2026. The distribution shows that the majority of patients report positive experiences, and the rating reflects real-world feedback across intake speed, provider communication, medication quality, and customer support.

In service-quality terms, Eden's 4.5-star average is the highest in this comparison, Henry Meds' 4.4 stars with the largest review base offers the most statistical confidence, and PlexusDx's 4.2 stars with a strong five-star concentration demonstrates consistent performance. No provider in this set shows a review profile that would categorically disqualify it on reliability grounds; differences of a few tenths of a star at this rating level often reflect sample composition and review-solicitation practices as much as true service gaps.

Money-back and outcome guarantees

Eden advertises a "Lose 10% in 6 months, or money back" pledge on its compounded plans, visible on the checkout page captured July 19, 2026. The full terms—what documentation is required, whether the guarantee applies to medication cost alone or also membership fees, and how the refund process works—are not detailed in the captured evidence. Patients considering Eden on the strength of this guarantee should request the complete terms before purchase.

Henry Meds and PlexusDx do not advertise outcome-based money-back guarantees in the captured evidence. Both offer the standard telehealth structure: free evaluation, charge only if prescribed, cancel anytime on month-to-month plans, and care coordination if the medication does not suit the patient. Neither provider guarantees a specific weight-loss result or timeline.

Choose Henry Meds if…

  • You want oral semaglutide at the lowest annual cost and are comfortable with a 12-month prepaid commitment ($1,788/year for sublingual or premium formulations).
  • You prefer injectable semaglutide with a one-year lock and are willing to pay upfront for a $197/month effective rate ($2,364 total).
  • You value a large Trustpilot review base (approximately 13,000 reviews at 4.4 stars) as a confidence signal.
  • You want transparent single-charge billing with no separate membership and straightforward cancellation on month-to-month terms.
  • You are interested in liraglutide or microdose GLP-1 options not offered by Eden or PlexusDx in this evidence set.

Choose Eden if…

  • You want month-to-month semaglutide (injectable or oral) at an ongoing $198 rate after a $138 first month (introductory first-month membership rate, verified July 19 and September 4, 2026) and accept a two-part billing structure.
  • You are comfortable with route availability determined by the clinician rather than locked at checkout, and you value flexibility over guaranteed formulation.
  • You want access to injectable tirzepatide on a month-to-month basis without prepay, and Henry Meds does not offer it.
  • You value a 10% weight-loss-in-6-months money-back pledge and are prepared to verify the full terms during intake.
  • You prefer the highest Trustpilot star average in this comparison (4.5 stars across ~5,000 reviews).

Where PlexusDx fits

PlexusDx sits between Henry Meds and Eden on month-to-month pricing for injectable semaglutide—$189 against Henry Meds' $297 and Eden's $198—and ties Henry Meds' best 12-month rate when comparing injectable semaglutide on a 6-month prepaid cycle ($1,788/year, our calculation). For injectable tirzepatide, PlexusDx is the middle option on month-to-month terms ($289 vs. Eden's $298) and the only provider in this set offering tirzepatide injectable prepaid discounts ($249/month on a 6-month prepaid plan). PlexusDx oral pricing is higher than both competitors, making it less competitive for patients prioritizing oral routes. The service model is a single all-inclusive charge, no membership fee, cancel anytime, with a 4.2-star Trustpilot rating (81% four stars or higher). PlexusDx works with licensed 503A compounding pharmacies and includes the standard compounded-medication disclosure.

For patients who want injectable semaglutide at the lowest month-to-month cost with flexible cancellation, PlexusDx is $9 below Eden and $108 below Henry Meds. For patients seeking injectable tirzepatide with prepaid savings, PlexusDx is the only option in this comparison offering 3-month and 6-month prepaid tiers. For oral GLP-1, Henry Meds and Eden both offer lower month-to-month and annual rates.

Methodology and freshness

This comparison uses publicly accessible pricing pages, checkout flows, legal terms, and Trustpilot profiles captured between July 19 and September 5, 2026. Henry Meds pricing was verified July 20 and September 4, 2026; Eden pricing was verified July 19 and September 4, 2026; PlexusDx pricing is current as of September 5, 2026. All 12-month cost totals are our calculation, derived by multiplying monthly rates or summing prepaid cycles; where first-month discounts apply, we show first-year and ongoing-year figures separately. Where evidence conflicts—such as Henry Meds oral tirzepatide term inconsistencies—we state the conflict and note that patients should confirm details at checkout. Review ratings and volumes are point-in-time captures and may shift as new feedback is published. No provider paid for placement or editorial angle; PlexusDx is one of the three providers discussed.

Frequently Asked Questions

Does Eden charge separately for the membership?

Yes. Eden bills medication and membership as two recurring charges. Semaglutide medication is $99/month, tirzepatide medication $199/month, and membership is $99/month after a $39 first-month introductory rate (verified July 19 and September 4, 2026). The combined ongoing cost is $198/month for semaglutide and $298/month for tirzepatide.

Can I get injectable tirzepatide from Henry Meds?

No. Henry Meds' captured medication list includes compounded semaglutide injection, oral semaglutide, oral tirzepatide, liraglutide injection, and microdose GLP-1 injection, but injectable tirzepatide is not offered. Eden and PlexusDx both provide injectable tirzepatide in this comparison.

What happens if I cancel a Henry Meds 12-month plan early?

Henry Meds' legal page states that multi-month prepaid plans "may be required to pay out the rest of your balance unless you're unable to continue for medical-related reasons as determined by a healthcare provider." The exact process and documentation required are not detailed; confirm with Henry Meds support before committing if early exit is a concern.

Does PlexusDx charge a membership fee?

No. PlexusDx pricing is all-inclusive—one monthly charge covers medication, provider visit, and shipping. There is no separate membership, subscription tier, or recurring administrative fee. You can cancel anytime on month-to-month plans without penalty.

How do I know if Eden will provide injectable vs. oral medication?

Eden's checkout and legal pages state that "injectable and oral availability varies" and is "route/availability clinician-dependent." This means route confirmation happens during the provider evaluation, not at purchase. If you require a specific formulation, ask the provider during intake to confirm availability before proceeding.

Sources

  • Henry Meds pricing and plan terms – captured July 20, 2026 and September 4, 2026
  • Henry Meds medication list and pharmacy disclosure – captured September 5, 2026
  • Henry Meds cancellation and shipping policies – captured September 5, 2026
  • Eden checkout flow, pricing, and membership terms – captured July 19, 2026 and September 4, 2026
  • Trustpilot ratings for Henry Meds, Eden, and PlexusDx – captured September 4, 2026
  • PlexusDx pricing and service structure – current as of September 5, 2026

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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