Last reviewed: May 12, 2026
Last updated: May 12, 2026
Written by:
Jay Hastings
,
CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by:
Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
This article is part of the PlexusDx Education Hub, where we publish evidence-based guidance on GLP-1 therapies, weight management protocols, and the genetic factors behind every metabolic decision. Browse all Peptides & GLP-1 education
This editorial review reads a Fridays price the way a pharmacist would, separating program fees from medication cost and adding up the real monthly total. Fair-balance editorial framing, not a buying recommendation. As of April 2026.
Full head-to-head: PlexusDx vs Fridays →
This is an independent editorial review. PlexusDx holds no commercial relationship with Fridays, earns no affiliate commission, and was not compensated to publish it.
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Reading a Fridays price the way a pharmacist would
A posted price is only useful once you know what sits inside it. Fridays (Fridays Health) runs a telehealth-plus-compounding model: a licensed clinician reviews your intake and issues a prescription filled either at a retail pharmacy for brand products or at a 503A compounding pharmacy for compounded semaglutide or tirzepatide. Each route carries its own pricing logic. Current figures live at Fridays' own website.
Program fee, medication, and the parts that bundle together
According to its pricing page (joinfridays.com/pricing, verified 2026-07-20), Fridays folds coaching, dietitian support, follow-up, free shipping, and a $0 membership into the advertised rate rather than itemizing them. Compounded semaglutide is listed at $249 per month and compounded tirzepatide at $359 per month on a month-to-month basis, so the headline number already includes the wrap-around services many programs bill on the side.
Where an itemized program hides its cost
When services are bundled, the compound becomes the visible cost while support services are invisible. That is convenient, but it also means the only way to lower the number materially is to change compound or change payment cadence.
Compounded versus brand: where the price actually comes from
Compounded semaglutide and tirzepatide come from 503A pharmacies and are priced independently of the FDA-approved brands. Brand products filled at retail follow separate, generally higher, pricing set outside the telehealth program. Knowing which one a quote refers to is the difference between comparing like with like and comparing two very different bills.
What total monthly cost really includes
Total cost is the compound plus anything not bundled, averaged across your payment term. Fridays says a paid-annually plan works out to about $150 per month for semaglutide and $240 for tirzepatide. For reference, PlexusDx month-to-month rates run roughly $60 to $70 below Fridays month-to-month for both compounds, and Fridays also sells prepaid three- and six-month bundles. Rates moved within a single day at our check, so verify before you decide.
Pricing without the genetic picture
A price tag answers what you pay, not how your body will meet the compound. Variants in GLP1R, the gene encoding the GLP-1 receptor that every one of these drugs targets, and in TCF7L2, a transcription factor linked to glucose control, describe the biology underneath the invoice. They do not forecast results or price, but they add pathway context. The Precision Peptide Genetic Test analyzes 14 pathways, 49 peptides, 150+ genetic insights, covering FTO, MC4R, and TCF7L2, so the number you agree to pay is paired with an understanding of your own metabolism.
The PlexusDx pricing approach for comparison
PlexusDx leads with clear month-to-month pricing on its Weight Management Protocols, including Semaglutide Injection and Tirzepatide Injection, rather than headlining a long prepaid floor. The differentiator is not a discount trick; it is the genetic layer offered alongside the medication.
No affiliation: PlexusDx is independent of Fridays and has no commercial ties to the brands discussed in this review.
More from the PlexusDx library: GLP-1 Drugs, What Is GLP-1.
Disclaimer: this article is educational. PlexusDx is not affiliated with Fridays and has no commercial relationship with the brands reviewed. PlexusDx offers semaglutide and tirzepatide through its own Weight Management Protocols, and this piece compares approaches within the GLP-1 telehealth space. The Precision Peptide Genetic Test analyzes how your genes influence peptide-related biological pathways; it does not predict response to any specific medication and is not a pharmacogenomic test. Speak with a qualified healthcare provider before beginning any peptide protocol.
Frequently Asked Questions About Fridays Pricing
What is included in a Fridays price?
The advertised price bundles the compound, clinical follow-up, coaching, and dietitian access, with $0 membership and free shipping according to the brand pricing page. That means the headline figure is closer to a total than a base fee, though the compound you pick still moves it substantially.
Is compounded semaglutide priced differently from brand?
Yes. Compounded semaglutide and tirzepatide are dispensed through a 503A pharmacy and priced separately from FDA-approved brand products filled at retail. Fridays lists compounded semaglutide at $249 and tirzepatide at $359 monthly; brand products carry their own, typically higher, retail pricing.
How do I calculate my true monthly total?
Add the compound rate to any add-ons, then divide prepaid bundles across their term. Fridays states annual prepay lands near $150 monthly for semaglutide and $240 for tirzepatide. Because rates shifted within a day on 2026-07-20, confirm each component on the live site.
Does the genetic test carry a separate price?
The Precision Peptide Genetic Test is a distinct PlexusDx product, not a Fridays line item, and it never predicts medication response. It reads pathway variants like TCF7L2 to give you baseline context before you commit spending to any GLP-1 protocol.
This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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Brello vs Fridays: Compounded GLP-1 Models Compared
Brello vs Fridays: Compounded GLP-1 Models Compared