Cheaper Alternatives to Sesame Care: GLP-1 Providers Compared

Last reviewed: September 17, 2026 Last updated: September 17, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Sesame Care operates as a national clinician marketplace offering weight-loss programs and prescriptions, but public search did not expose a stable monthly all-in medication price as of September 4, 2026. Pricing appears to vary by location and requires intake or checkout to quote. In contrast, seven verified alternatives publish transparent recurring rates ranging from $129 to $399 per month for compounded GLP-1 medications, with all visits, prescriptions, medication, and shipping included. PlexusDx compounded semaglutide injection is $189/month month-to-month ($149/month on a 6-month commitment), and microdose GLP-1 at $129/month—both below most marketplace and subscription programs in the verified cohort.

At-a-glance comparison

Pricing captured July 17–23, 2026, and September 4, 2026. All figures are month-to-month (MTM) all-inclusive rates except where labeled prepaid. Compounded medications only; branded GLP-1 prescriptions not included in this comparison.

Why Sesame Care pricing is difficult to compare

Sesame Care functions as a marketplace connecting patients with independent clinicians for cash-pay services, including weight-loss consultations and prescriptions. As of September 4, 2026, public search did not expose a stable all-in monthly medication price. Visit fees, program enrollment, and prescription costs appear to vary by provider, location, and patient needs, requiring intake or checkout to generate a location-specific quote. This model offers flexibility but makes direct price comparison against subscription programs with published rates impossible without completing the intake process.

Transparent alternatives: verified monthly costs

Seven verified GLP-1 telehealth providers publish checkout-confirmed or advertised monthly rates that include clinician visits, prescriptions, compounded medication, and shipping. These programs eliminate guesswork and allow side-by-side cost evaluation before intake.

PlexusDx: $189/month semaglutide, $289/month tirzepatide (month-to-month)

PlexusDx charges $189 per month for compounded semaglutide injection on a month-to-month plan, $169/month on a 3-month commitment, and $149/month on a 6-month commitment. Compounded tirzepatide injection is $289/month month-to-month, $269/month on 3-month, and $249/month on 6-month. Oral semaglutide capsules cost $289/month month-to-month ($269 on 3-month, $249 on 6-month), and oral tirzepatide capsules $349/month month-to-month ($299 on 3-month, $279 on 6-month). Microdose GLP-1 injection—a lower-dose option for maintenance or mild weight goals—is $129/month with no multi-month discounts. Every plan charges the same price at every dose, with no membership fee and no separate visit, lab, or shipping charges. Advertised price and ongoing price are identical.

12-month cost (our calculation):

• Semaglutide injection MTM: $189 × 12 = $2,268/year
• Semaglutide injection 6-month: $149 × 12 = $1,788/year (saves $480 vs MTM)
• Tirzepatide injection MTM: $289 × 12 = $3,468/year
• Tirzepatide injection 6-month: $249 × 12 = $2,988/year (saves $480 vs MTM)
• Microdose GLP-1: $129 × 12 = $1,548/year

Eden: $198/month semaglutide, $298/month tirzepatide

Eden advertises compounded medication at $99/month but requires a $99/month membership, bringing the all-in cost to $198/month for semaglutide and $298/month for tirzepatide. The membership covers clinician access, messaging support, and prescription management.

12-month cost (our calculation):

• Semaglutide: $198 × 12 = $2,376/year (+$108 vs PlexusDx MTM, +$588 vs PlexusDx 6-month)
• Tirzepatide: $298 × 12 = $3,576/year (+$108 vs PlexusDx MTM, +$588 vs PlexusDx 6-month)

Found: $289/month semaglutide month-to-month; 12-month prepaid plan at $169/month

Found's cash-pay track charges $289/month for compounded semaglutide and $359/month for compounded tirzepatide on a month-to-month basis. A 12-month prepaid plan offers $169 per month for semaglutide, requiring $2,028 upfront. (Found also offers an insurance track advertised "from $99," but that figure reflects insurance copays and is not comparable to cash pricing.)

12-month cost (our calculation):

• Semaglutide MTM: $289 × 12 = $3,468/year (+$1,200 vs PlexusDx MTM, +$1,680 vs PlexusDx 6-month)
• Semaglutide 12-month prepaid: $169 × 12 = $2,028/year (identical to PlexusDx 3-month effective rate; +$240 vs PlexusDx 6-month; requires $2,028 upfront)
• Tirzepatide MTM: $359 × 12 = $4,308/year (+$840 vs PlexusDx MTM, +$1,320 vs PlexusDx 6-month)

Henry Meds: $297/month semaglutide

Henry Meds charges $297/month for compounded semaglutide injection, covering medication, shipping, and provider access with no separate membership fee. Tirzepatide is offered as an oral dissolving tablet only; no published monthly rate for tirzepatide injection was captured in the July 2026 verification.

12-month cost (our calculation):

• Semaglutide: $297 × 12 = $3,564/year (+$1,296 vs PlexusDx MTM, +$1,776 vs PlexusDx 6-month)

Peak Wellness: $249/month semaglutide, $349/month tirzepatide

Peak Wellness lists $249/month for compounded semaglutide and $349/month for compounded tirzepatide on month-to-month plans. Lower per-month rates are available on 6-month prepaid plans, though specific prepaid figures were not checkout-verified in the July 2026 capture.

12-month cost (our calculation):

• Semaglutide: $249 × 12 = $2,988/year (+$720 vs PlexusDx MTM, +$1,200 vs PlexusDx 6-month)
• Tirzepatide: $349 × 12 = $4,188/year (+$720 vs PlexusDx MTM, +$1,200 vs PlexusDx 6-month)

TrimRx: checkout-verified ongoing rates of $299/month semaglutide, $399/month tirzepatide

TrimRx advertises $199 for semaglutide and $349 for tirzepatide, but checkout verification in July 2026 showed ongoing billing at $299/month for semaglutide and $399/month for tirzepatide. Lower per-month rates are available on 3-, 6-, and 12-month plans charged upfront.

12-month cost, checkout-verified ongoing rates (our calculation):

• Semaglutide: $299 × 12 = $3,588/year (+$1,320 vs PlexusDx MTM, +$1,800 vs PlexusDx 6-month)
• Tirzepatide: $399 × 12 = $4,788/year (+$1,320 vs PlexusDx MTM, +$1,800 vs PlexusDx 6-month)

Embody: $299/month semaglutide, $349/month tirzepatide

Embody charges $299/month for compounded semaglutide and $349/month for compounded tirzepatide with no membership fee. Pricing is stable at every dose, and advertised rates match ongoing billing.

12-month cost (our calculation):

• Semaglutide: $299 × 12 = $3,588/year (+$1,320 vs PlexusDx MTM, +$1,800 vs PlexusDx 6-month)
• Tirzepatide: $349 × 12 = $4,188/year (+$720 vs PlexusDx MTM, +$1,200 vs PlexusDx 6-month)

Decision factors: pricing transparency, flexibility, and route options

Pricing transparency

Sesame Care's marketplace model means pricing depends on which clinician you match with and what services they bundle. This structure may work well for patients who value provider choice over predictable costs, but it requires intake or checkout to learn your monthly medication expense. Every alternative in the verified cohort publishes at least an advertised rate before intake—and most publish stable recurring rates that match checkout billing.

Flexibility and commitment

PlexusDx, Eden, Embody, Henry Meds, and Peak Wellness all offer month-to-month billing with no upfront commitment. Found and TrimRx advertise lower per-month rates on prepaid plans (12-month for Found, 3- to 12-month for TrimRx), which reduce the effective monthly cost but require hundreds or thousands of dollars upfront and limit the ability to pause or cancel without forfeiting prepaid funds.

Medication route and dose

All verified providers except Henry Meds offer compounded semaglutide and tirzepatide injections. Henry Meds offers tirzepatide as an oral dissolving tablet only. PlexusDx also offers oral semaglutide and tirzepatide capsules ($289 and $349 month-to-month, respectively) and microdose GLP-1 injection at $129/month for maintenance or patients who need a lower starting dose. Most programs adjust dose over time; PlexusDx, Embody, and others charge the same monthly price regardless of dose, while programs that tie price to dose or tier may increase cost as you titrate up.

Membership fees

Eden requires a $99/month membership in addition to the $99 medication charge, bringing all-in cost to $198 (semaglutide) or $298 (tirzepatide). PlexusDx, Found (cash track), Henry Meds, Peak Wellness, TrimRx, and Embody include clinician access, prescription management, and shipping in the medication price with no separate membership fee.

Choose Sesame Care if…

• You prefer selecting your own clinician from a marketplace rather than being assigned to a provider by a subscription service.
• You are willing to complete intake or checkout to receive a location-specific cost quote before deciding.
• You value the flexibility of a cash-pay visit model over predictable subscription billing.
• You are exploring branded GLP-1 prescriptions (e.g., Wegovy, Zepbound) rather than compounded medications; Sesame Care's marketplace may connect you with providers who prescribe branded drugs when appropriate and covered by insurance or affordable out-of-pocket.

Choose Eden if…

• You want integrated messaging support and health coaching bundled into a membership.
• The $198/month (semaglutide) or $298/month (tirzepatide) all-in cost fits your budget and you value the membership services.
• You prefer a program that separates medication and support services into distinct line items.

Choose Found if…

• You are willing to prepay 12 months upfront ($2,028 for semaglutide) to achieve a $169/month effective rate—matching PlexusDx's 3-month commitment price.
• You prefer a program that integrates behavioral health coaching and nutrition support alongside medication.
• Your insurance may cover part of the cost; Found offers both cash-pay and insurance tracks, though cash pricing is higher than most alternatives on a month-to-month basis.

Choose Henry Meds if…

• You are comfortable with semaglutide injection at $297/month and do not need tirzepatide injection.
• You prefer a subscription model that bundles medication, provider access, and shipping with no separate fees.
• You are open to oral dissolving tirzepatide tablets if you want to try tirzepatide and your provider recommends that route.

Choose Peak Wellness if…

• $249/month for semaglutide or $349/month for tirzepatide fits your budget and you want a straightforward subscription with no membership fee.
• You are willing to prepay 6 months to access lower per-month rates (specific prepaid rates require checkout verification).
• You value a no-frills program that focuses on medication delivery and clinical oversight without extensive coaching or behavioral support.

Choose TrimRx if…

• You can prepay 3, 6, or 12 months to access per-month rates below the $299/$399 ongoing checkout-verified pricing.
• You are comfortable with a program whose advertised rate differs from its checkout-verified ongoing rate; confirm your specific recurring cost before committing.
• You want a subscription that includes medication and provider access with no separate membership.

Choose Embody if…

• $299/month for semaglutide or $349/month for tirzepatide fits your budget.
• You value same-price-at-every-dose simplicity and want no surprises as your provider adjusts your prescription.
• You prefer a program with transparent published rates that match ongoing billing.

Choose PlexusDx if…

• You want the lowest verified month-to-month cost for compounded semaglutide injection ($189) or compounded tirzepatide injection ($289) with no membership fee, no separate visit or lab charges, and no prepayment requirement.
• You want the option to commit to 3 or 6 months for additional savings ($149/month semaglutide, $249/month tirzepatide on 6-month plans) while retaining predictable monthly billing.
• You are interested in oral GLP-1 capsules or microdose GLP-1 ($129/month) for maintenance or lower starting doses.
• You value pricing transparency: advertised price, ongoing price, and every-dose price are identical, and every cost component is published before intake.
• You prefer working with a program that uses 503A compounding pharmacies and licenses providers in your state to prescribe and manage your medication remotely.

PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com).

Methodology and freshness

Sesame Care marketplace and program details were captured from sesamecare.com on September 4, 2026. Public search did not expose a stable monthly all-in medication price; evidence status is marked "Intake/ambiguous," requiring location-specific quote at checkout. Verified alternative pricing (Eden, Embody, Found, Henry Meds, Peak Wellness, TrimRx) was captured from provider websites and checkout flows between July 17 and July 23, 2026. PlexusDx pricing was captured from plexusdx.com on September 17, 2026. All 12-month cost calculations are ours, derived by multiplying stated monthly rates by 12. Prepaid per-month rates are labeled as prepaid and are our calculation. We recommend confirming current pricing, medication availability, provider licensing in your state, and cancellation terms at each provider's checkout before committing. If you observe a price conflict between this article and a provider's live checkout, the checkout figure controls and we ask that you notify us so we can update the comparison.

Frequently Asked Questions

Why doesn't Sesame Care publish a monthly GLP-1 medication price?

Sesame Care functions as a marketplace connecting patients with independent clinicians who set their own fees and service bundles. Visit costs, program enrollment, and prescription fulfillment vary by provider and location, so the platform does not display a single stable monthly medication rate. You receive a specific quote after completing intake or selecting a clinician.

Can I get branded Wegovy or Zepbound instead of compounded semaglutide or tirzepatide?

Sesame Care's marketplace may connect you with providers who prescribe branded GLP-1 medications when clinically appropriate and covered by insurance or affordable out-of-pocket. The seven verified alternatives in this comparison offer compounded semaglutide and tirzepatide, which are not FDA-approved and are distinct from branded drugs. A licensed clinician determines whether a prescription is appropriate for an individual patient.

What is the cheapest verified GLP-1 program with published pricing?

PlexusDx microdose GLP-1 injection is $129/month with no membership fee, visit charges, or prepayment. For full-dose semaglutide, PlexusDx charges $189/month month-to-month or $149/month on a 6-month commitment. For tirzepatide, PlexusDx is $289/month month-to-month or $249/month on 6-month. All figures include clinician visits, prescription, medication, and shipping.

Do advertised prices match ongoing refill costs?

PlexusDx, Eden, Embody, Henry Meds, and Peak Wellness advertised rates matched checkout-verified ongoing billing in the July and September 2026 captures. TrimRx advertised $199 semaglutide and $349 tirzepatide but billed $299 and $399 ongoing at checkout. Found's month-to-month rates ($289 semaglutide, $359 tirzepatide) are stable; the advertised $169 semaglutide figure is a per-month rate for a 12-month prepaid plan requiring $2,028 upfront. Always confirm your specific recurring rate at checkout.

Are compounded GLP-1 medications FDA-approved?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. Compounded semaglutide and tirzepatide are not the same as branded Wegovy, Ozempic, Zepbound, or Mounjaro. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Sources

• PlexusDx pricing and program details – plexusdx.com – accessed September 17, 2026
• Sesame Care marketplace overview – sesamecare.com – accessed September 4, 2026
• Eden, Embody, Found, Henry Meds, Peak Wellness, TrimRx pricing verification – provider websites and checkout flows – accessed July 17–23, 2026
• PlexusDx Trustpilot rating – trustpilot.com/review/plexusdx.com – accessed September 9, 2026

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.