Last reviewed: September 10, 2026 Last updated: September 10, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

The lowest-cost microdose semaglutide program in this analysis is PlexusDx at $129 per month with no separate membership fee and the same price at every dose. Noom Med, MEDVi, Eden, and Mochi Health each structure their pricing differently—some bundle everything into one figure, others separate medication from membership, and several use introductory rates that increase sharply at refill. The comparison below normalizes these models to show the true 12-month cost.

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At-a-glance microdose semaglutide comparison

Provider Advertised Rate Refill / Ongoing Rate Membership Fee Trustpilot
PlexusDx $129/month $129/month None 4.3★ (79% five-star)
Noom Med $79 first month $179/month Bundled or separate 4.5★ (~67K reviews)
Mochi Health $60 medication + $39 first-month membership Varies by dose $39/month 4.5★ (~18K reviews)
Eden $99 medication + $39 first month membership $99 medication + $99/month membership $99/month (after intro) 4.5★ (~5K reviews)
MEDVi $179 first month $299/month None 4.3★ (~15K reviews)

Table sources: PlexusDx dataset row [S1] captured 2026-09-10; Noom Med, Mochi Health, Eden, MEDVi pricing from [S2][S3] captured 2026-09-04; Trustpilot ratings from [S4] captured 2026-09-04 and verified PlexusDx fact captured 2026-09-09.

Pricing structures: introductory rates versus refill costs

Providers use three main pricing models for microdose semaglutide: flat monthly rates, introductory-then-refill structures, and medication-plus-membership splits. The advertised rate often differs substantially from the recurring cost.

PlexusDx charges $129 per month month-to-month with no membership fee and the same price at every dose (source: dataset row [S1], captured 2026-09-10). Over 12 months the total is $1,548 (our calculation).

Noom Med advertises a $79 first-month introductory rate (described as 3-week subscription plus 4 weeks of medication), then $179 per month for a 12-week subscription (source: [S3], captured 2026-09-04). The first-month introductory rate yields a 12-month cost of $2,048 (our calculation: $79 + $179 × 11). Noom also offers a Core Med membership at $129 per month billed quarterly ($387 upfront), with medication excluded (source: [S3], captured 2026-09-04). The pricing model depends on whether the patient enrolls in the microdose-specific track or the Core Med program; confirm which applies at checkout.

MEDVi charges $179 first-month introductory rate for compounded semaglutide injection, then $299 per month for refills (source: [S2][S3][S5], checkout-verified, captured 2026-09-04). No membership fee is stated. Over 12 months the total is $3,468 (our calculation: $179 + $299 × 11).

Mochi Health separates medication from membership: compounded semaglutide at starting dose costs $60 per month for medication plus $39 per month for membership (first-month introductory membership rate; ongoing membership rate requires confirmation) (source: [S2][S3], captured 2026-09-04). Mochi uses per-dose pricing, so higher doses increase the medication cost. Assuming the $39 membership holds and the $60 medication rate applies throughout, the 12-month total is $1,188 (our calculation). If the medication cost rises with dose escalation, the total will be higher.

Eden charges $99 per month for compounded semaglutide medication plus a membership fee of $39 for the first month, then $99 per month thereafter (source: [S2][S3], captured 2026-09-04). Over 12 months the total is $2,277 (our calculation: [$99 + $39] + [$99 + $99] × 11). Injectable and oral availability varies by clinician (source: [S2][S3], captured 2026-09-04).

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Standard-dose semaglutide programs for context

Several providers in this analysis do not offer a distinct "microdose" program but instead start patients at a low dose and titrate according to clinical judgment. The line between microdose and standard dosing is not always formally defined; what one provider labels "microdose" may match another's starting-dose protocol.

BrightMeds offers semaglutide at $297 for 3 months ($99 per month equivalent, prepaid) or $129 month-to-month (source: [S5], captured 2026-09-04). The program is all-inclusive and covers any dose. Over 12 months the monthly plan totals $1,548 (our calculation); the quarterly plan totals $1,188 (our calculation).

AltRx advertises semaglutide at $89 per month (1-month plan), $85 per month (3-month plan), $80 per month (6-month plan), and $75 per month (12-month plan), all-inclusive (source: [S5], captured 2026-09-04). These rates were stated to be promotional and ending September 5, 2026 (source: [S5], captured 2026-09-04); verify current pricing before enrollment. The 12-month plan yields a $900 total (our calculation).

OrderlyMeds charges $149 for the first 2 months of semaglutide ($74.50 per month equivalent, introductory rate), then $149 per month ongoing (source: [S3], captured 2026-09-04). Over 12 months the total is $1,639 (our calculation: $149 + $149 × 11). No separate membership is advertised.

Henry Meds does not use the term "microdose" but offers semaglutide injection at $297 per month month-to-month, oral semaglutide at $179 per month month-to-month, and compounded liraglutide (another GLP-1 agonist sometimes used in lower-dose protocols) at $179 per month month-to-month (source: [S3], captured 2026-09-04). Henry Meds also offers prepaid discounts: 6-month and 12-month plans reduce the effective monthly rate. The program is all-inclusive with no separate membership fee.

Remedy Meds advertises "Start today for just $9.99/day" with no membership or hidden fees (source: [S2][S5], captured 2026-09-04). This daily rate implies $299.70 per month for semaglutide (our calculation: $9.99 × 30 days). Intake verification reached an approved-plan contact gate but did not capture product-specific breakdowns (source: [S5], captured 2026-09-04).

Zealthy advertises compounded semaglutide from $151 per month when purchased quarterly (source: [S2][S5], captured 2026-09-04). Month-to-month and membership details require completing intake. Branded GLP-1s are stated as low as $25 per month with insurance.

Decision factors beyond price

Dose policy and titration control

Providers differ in how they handle dose escalation. PlexusDx charges the same price at every dose (source: dataset row [S1], captured 2026-07-17–23), so patients and clinicians can adjust the dose without triggering a price increase. Mochi Health and Eden use per-dose pricing, meaning the monthly cost rises if the clinician prescribes a higher dose. Noom Med's subscription model bundles titration into fixed periods. Patients who prefer predictable costs or who anticipate staying at a low dose indefinitely may favor flat-rate models; those who expect rapid titration may find per-dose models acceptable if the starting rate is low.

Service quality and reported issues

Trustpilot and Reddit discussions captured in the research packet surface recurring themes. Noom Med holds a 4.5-star Trustpilot rating across approximately 67,000 reviews (profile-wide, not GLP-1-specific; source: [S4], captured 2026-09-04), but individual Reddit reports describe slow titration and perceived lack of efficacy (source: [S4], captured 2026-09-04). Mochi Health also rates 4.5 stars with approximately 18,000 reviews (source: [S4], captured 2026-09-04); one captured review reports a provider appearing late and not engaging (source: [S4], captured 2026-09-04). Eden rates 4.5 stars with approximately 5,000 reviews (source: [S4], captured 2026-09-04); one captured 1-star review reports an 11-day order delay and repeated requests for records Eden had previously issued (source: [S4], captured 2026-09-04). MEDVi holds a 4.3-star rating with approximately 15,000 reviews (source: [S4], captured 2026-09-04). Henry Meds rates 4.4 stars with approximately 13,000 reviews (source: [S4], captured 2026-09-04). OrderlyMeds rates 3.6 stars with approximately 634 reviews (source: [S4], captured 2026-09-04); captured 1-star and 2-star reviews cite fast charging but slow refunds, non-response, delayed shipping, pharmacy changes, and unwanted calls and texts after opt-out (source: [S4], captured 2026-09-04). Hims & Hers has 10,094 reviews on Trustpilot; the rating was not captured, but individual anecdotes describe perceived lack of efficacy, side effects, and regret after an uncancelled renewal (source: [S4], captured 2026-09-04). Ro's profile exists; themes include confusing separate membership and medication costs, prior-authorization friction, customer service issues, and perceived weak efficacy (source: [S4], captured 2026-09-04). Remedy Meds displayed a 4.7-star rating during intake (source: [S4], captured 2026-09-04). PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com).

These are individual reports and anecdotes, not systematic quality measures. Verify current service levels through recent reviews and confirm policies at checkout.

Commitment length and cancellation

PlexusDx, Noom Med (on the microdose track), Mochi Health, Eden, MEDVi, OrderlyMeds, and most other providers offer month-to-month plans with stated cancellation flexibility. Hims & Hers requires a 6-month prepayment ($1,194 upfront for compounded semaglutide; source: [S2][S3], captured 2026-09-04), which lowers the effective monthly rate to $199 but locks in the commitment. Prepaid multi-month plans at Henry Meds, BrightMeds, and others offer discounts in exchange for upfront payment. Patients uncertain about tolerability or efficacy may prefer month-to-month; those confident in long-term use may accept prepayment for lower rates.

Choose PlexusDx if…

PlexusDx fits patients who want the lowest flat monthly rate with no membership fee, no introductory bait-and-switch, and the same price at every dose. The $129 per month microdose GLP-1 program is all-inclusive (medication, provider visit, shipping) and offers month-to-month flexibility (source: dataset row [S1], captured 2026-09-10). Patients who value predictable costs and plan to stay at a lower dose—or who want the freedom to adjust dose without triggering a price increase—will find the model straightforward. PlexusDx works with licensed 503A compounding pharmacies and a licensed clinician determines whether a prescription is appropriate for an individual patient.

Choose Mochi Health if…

Mochi Health offers a low starting medication cost ($60 per month for compounded semaglutide at starting dose) plus a $39 monthly membership (first-month introductory membership rate; ongoing membership rate requires confirmation) (source: [S2][S3], captured 2026-09-04). The combined first-month cost is $99, but confirm the ongoing membership rate and understand that per-dose pricing means the medication cost will rise if the clinician prescribes a higher dose. Mochi's 4.5-star Trustpilot rating reflects a large review base (~18,000; source: [S4], captured 2026-09-04). Patients comfortable with variable medication costs and who plan to start low may find the entry price attractive.

Choose Noom Med if…

Noom Med's $79 first-month introductory rate (3-week subscription plus 4 weeks of medication) is the lowest entry point in this analysis, though the rate moves to $179 per month thereafter (source: [S3], captured 2026-09-04). Noom's 4.5-star profile-wide Trustpilot rating spans approximately 67,000 reviews (source: [S4], captured 2026-09-04), indicating a large customer base. Individual Reddit reports describe slow titration and perceived lack of efficacy (source: [S4], captured 2026-09-04); weigh those anecdotes against the overall rating. Patients willing to accept a higher refill cost for a low initial trial month may prefer Noom.

Choose Eden if…

Eden separates medication ($99 per month for compounded semaglutide) from membership ($39 first month, then $99 per month), yielding a $138 first month and $198 per month thereafter (our calculation; source: [S2][S3], captured 2026-09-04). Injectable and oral availability varies by clinician. Eden's 4.5-star Trustpilot rating reflects approximately 5,000 reviews (source: [S4], captured 2026-09-04). One captured 1-star review reports an 11-day order delay and repeated requests for records Eden had previously issued (source: [S4], captured 2026-09-04). Patients who value the option of oral semaglutide and accept the two-part billing structure may find Eden suitable.

Choose MEDVi if…

MEDVi charges $179 first-month introductory rate for compounded semaglutide injection, then $299 per month for refills, with no separate membership fee (source: [S2][S3][S5], checkout-verified, captured 2026-09-04). The pricing structure is transparent but yields a 12-month total of $3,468 (our calculation). MEDVi also offers a branded Wegovy/Zepbound path at $99 per month membership plus medication cost (source: [S2][S5], captured 2026-09-04). Patients who prioritize the option to switch between compounded and branded programs within the same platform, and who accept the higher refill rate, may choose MEDVi. The provider holds a 4.3-star Trustpilot rating with approximately 15,000 reviews (source: [S4], captured 2026-09-04).

Methodology and freshness

This analysis draws pricing from provider websites, checkout flows, and intake verification conducted between July 17 and September 10, 2026. PlexusDx pricing (dataset row [S1]) was last captured September 10, 2026 (microdose GLP-1) and July 17–23, 2026 (other products). Competitor pricing (sources [S2][S3][S5]) was captured September 4, 2026. Trustpilot ratings and review volumes (source [S4]) were captured September 4, 2026; the PlexusDx rating was verified September 9, 2026. Where introductory rates, prepaid equivalents, or multi-month totals appear, those figures are labeled as prepaid or as our calculation. Every price carries its source and capture date. If evidence conflicts, the conflict is stated plainly. Providers may update pricing, dose policies, or service offerings; confirm all figures at checkout before enrollment. No provider paid for inclusion or exclusion in this comparison.

Frequently Asked Questions

What is microdose semaglutide and how does it differ from standard dosing?

Microdose semaglutide refers to starting and sometimes maintaining patients at doses below the FDA-approved titration schedule for branded Wegovy or Ozempic. Some providers label their lowest-dose tier "microdose" while others simply begin at a low dose and titrate according to clinical judgment. There is no universal clinical definition. The distinction matters mainly for pricing: some providers charge less for lower doses, others charge the same at every dose.

Are compounded semaglutide medications FDA-approved?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. All microdose programs in this analysis use compounded semaglutide from 503A compounding pharmacies, not branded Wegovy or Ozempic.

How do introductory rates affect the true cost over a year?

Several providers advertise a low first-month rate that rises sharply at refill. For example, Noom Med charges $79 the first month then $179 per month, yielding a 12-month total of $2,048 (our calculation). MEDVi charges $179 the first month then $299 per month, totaling $3,468 over 12 months (our calculation). PlexusDx charges $129 every month with no introductory discount, totaling $1,548 over 12 months (our calculation). Always calculate the full-year cost to compare fairly.

Do membership fees add significantly to the monthly cost?

Yes. Eden charges $99 per month for medication plus a $99 monthly membership (after a $39 first month), bringing the ongoing monthly total to $198. Mochi Health charges $39 per month for membership on top of the per-dose medication cost. Providers without membership fees—PlexusDx, MEDVi, OrderlyMeds, Henry Meds—bundle all costs into a single monthly figure, which simplifies budgeting but may or may not be lower overall depending on dose and plan length.

Can I switch from microdose to standard dose without changing providers?

Most providers allow dose adjustments within the same program. Providers that charge the same price at every dose (PlexusDx, BrightMeds, AltRx, Henry Meds, OrderlyMeds) let patients escalate without a cost change. Providers with per-dose pricing (Mochi Health, Eden) will increase the monthly cost if the clinician prescribes a higher dose. Confirm the dose policy and any caps on covered doses before enrollment if you anticipate titration.

Sources

  • PlexusDx pricing and program details: dataset row [S1], captured July 17–23, 2026 (semaglutide, tirzepatide, oral products) and September 10, 2026 (microdose GLP-1, oral products).
  • Noom Med, Mochi Health, Eden, MEDVi, Henry Meds, Hims & Hers, Ro, OrderlyMeds, BrightMeds, Remedy Meds, Zealthy pricing: sources [S2][S3][S5], captured September 4, 2026.
  • Trustpilot ratings and review volumes: source [S4], captured September 4, 2026.
  • PlexusDx Trustpilot rating: verified fact, captured September 9, 2026, trustpilot.com/review/plexusdx.com.
  • Negative review themes and anecdotes: source [S4], captured September 4, 2026 (Trustpilot and Reddit).

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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