Last reviewed: September 7, 2026 Last updated: September 7, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Nine telehealth providers offer true month-to-month compounded GLP-1 programs with no multi-month contract or upfront commitment: PlexusDx, MEDVi, Henry Meds, Eden, Embody, Peak Wellness, TrimRx, Found, and Fridays Health. Among these, PlexusDx ($189/month semaglutide, $289/month tirzepatide), MEDVi ($299/month semaglutide refill, $399/month tirzepatide refill after introductory first months), and Henry Meds ($297/month semaglutide) represent the clearest month-to-month structures with no separate membership fees. Several others—Eden, Embody, Peak Wellness, TrimRx, and Fridays Health—also accept month-to-month commitments, but pricing varies from $249 to $399 for the two lead compounds depending on the provider and medication.

The critical distinction: many competitors advertise low monthly figures that require 3-, 6-, or 12-month prepayment—those plans fall outside this no-contract roundup. This article compares only month-to-month rates verified at checkout or on public pricing pages as of September 2026, identifying programs you can cancel at any time without forfeiting prepaid months.

Starting GLP-1 therapy without a long-term lock-in?

Compare PlexusDx's month-to-month semaglutide, tirzepatide, and microdose protocols—fixed pricing at every dose, cancel anytime.

View Month-to-Month Protocols →

Month-to-month pricing at a glance

The table below shows verified month-to-month rates only. Where a provider offers a discounted first month, both the introductory rate and the refill rate appear; the effective cost over 12 months accounts for one introductory month followed by eleven refill months. All figures captured September 2026 unless noted.

Provider Semaglutide Injection Tirzepatide Injection Separate Membership 12-Month Total (Sema)
PlexusDx $189/month $289/month None $2,268
MEDVi $179 first month, then $299/month refill $279 first month, then $399/month refill None (compounded path) $3,468 (our calculation)
Henry Meds $297/month Oral tablet only, 3-month minimum None $3,564
Eden $99/month medication + $99/month membership ($198 total ongoing; $39 first membership month) $199/month medication + $99/month membership ($298 total ongoing; $39 first membership month) $99/month ($39 introductory first month) $2,316 (our calculation: $138 first month + $198×11)
Embody $299/month $349/month None $3,588
Peak Wellness $249/month $349/month None $2,988
TrimRx $299/month at checkout (advertised $199) $399/month at checkout (advertised $349) None $3,588
Found $289/month (cash-pay, medication included) $359/month (cash-pay, medication included) Medication bundled $3,468
Fridays Health $249/month $359/month None $2,988

Sources: PlexusDx pricing page (captured 2026-09-07); MEDVi checkout verification (captured 2026-09-04); Henry Meds pricing page (captured 2026-09-04); Eden pricing page (captured 2026-09-04); Embody checkout verification (2026-09-07); Peak Wellness checkout verification (2026-09-07); TrimRx checkout verification (2026-09-07); Found pricing page (2026-09-07); Fridays Health pricing page (2026-09-07).

Normalized 12-month cost comparison

Several providers offer discounted first months or separate medication and membership fees; the table below normalizes these structures to show the true recurring cost over one year of month-to-month treatment for semaglutide injection.

Provider First-Month Total Months 2–12 Each 12-Month Total Effective Monthly
PlexusDx $189 $189 $2,268 $189 (our calculation)
MEDVi $179 $299 $3,468 $289 (our calculation)
Henry Meds $297 $297 $3,564 $297
Eden $138 introductory first month ($99 medication + $39 membership first month), then $198 ongoing ($99 medication + $99 membership) $198 ($99 medication + $99 membership) $2,316 (our calculation: $138 first month + $198×11) $193 (our calculation)
Embody $299 $299 $3,588 $299
Peak Wellness $249 $249 $2,988 $249
TrimRx $299 at checkout $299 $3,588 $299
Found $289 $289 $3,468 $289
Fridays Health $249 $249 $2,988 $249

Effective monthly figures are our calculation, dividing the 12-month total by 12. All figures assume month-to-month payment with no prepaid commitment.

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

See if you qualify for $189/month semaglutide or $289/month tirzepatide

A licensed provider reviews your intake and determines whether a prescription is appropriate for you.

Start My 60-Second Intake →

About 60 seconds · $0 charged until provider approval.

What to watch beyond the headline rate

Introductory pricing versus refill pricing

MEDVi's advertised semaglutide rate of $179 applies only to the first month; the refill rate jumps to $299, raising the effective monthly cost over a year to $289 (our calculation). Patients who see the $179 figure and budget month-to-month accordingly may face a 67% increase at the second refill. PlexusDx, Henry Meds, Embody, Peak Wellness, Found, and Fridays Health hold the same rate from first month through refills.

Separate membership fees

Eden charges a separate $99/month membership on top of $99/month semaglutide medication (total $198 ongoing after a $39 introductory first-month membership discount). The two-component structure can complicate budgeting, and cancellation policies may differ for membership versus medication. PlexusDx, MEDVi (on the compounded path), Henry Meds, Embody, Peak Wellness, TrimRx, and Fridays Health bundle all costs into a single monthly charge with no separate membership.

Advertised price versus checkout price

TrimRx advertises semaglutide at $199 and tirzepatide at $349, but checkout verification captured $299 semaglutide and $399 tirzepatide on September 7, 2026. The advertised figures may apply to multi-month plans or promotional periods; readers should verify the month-to-month rate at the payment step before committing.

Route availability and dose ceilings

Henry Meds offers semaglutide injection month-to-month but restricts tirzepatide to oral dissolving tablets available only on a 3-month prepaid plan—tirzepatide injection is not offered. If you prefer tirzepatide injection with no contract, Henry Meds does not qualify. PlexusDx, MEDVi, Eden, Embody, Peak Wellness, TrimRx, Found, and Fridays Health all offer tirzepatide injection month-to-month.

Some providers tie pricing to dose tiers; Mochi Health, for example, charges per dose level rather than a flat monthly rate, which can raise costs mid-treatment when a clinician increases the dose. PlexusDx, MEDVi, and Embody explicitly hold the same price at every dose, eliminating mid-treatment surprises.

Month-to-month versus prepaid plans

Many providers advertise low effective monthly rates that require 3-, 6-, or 12-month prepayment. These plans fall outside this roundup's no-contract scope but merit brief mention for readers comparing flexibility against cost:

  • PlexusDx: 3-month semaglutide injection $169/month effective ($507 prepaid), 6-month $149/month effective ($894 prepaid); 3-month tirzepatide injection $269/month effective ($807 prepaid), 6-month $249/month effective ($1,494 prepaid).
  • Found: annual cash-pay plan $169/month effective ($2,028 prepaid), a $1,440 savings versus month-to-month over 12 months but requires full upfront payment and forfeits flexibility to cancel mid-year.
  • Hims & Hers: compounded semaglutide $199/month effective requires 6-month prepayment ($1,194 upfront), eliminating month-to-month cancellation rights.
  • BrightMeds: advertises semaglutide $129/month month-to-month and $99/month effective on a 3-month prepaid plan ($297 upfront), a structure that qualifies for this roundup's month-to-month tier—however, full checkout verification was not completed as of September 2026, and readers should confirm the $129 rate holds at the payment step.

Prepaid plans lock in a lower per-month rate but require upfront capital and eliminate the ability to stop treatment or switch providers mid-cycle without forfeiting prepaid months. Month-to-month plans preserve flexibility at the cost of a higher effective rate.

Service quality and support responsiveness

Price is one dimension; service quality, support responsiveness, and order reliability form the operational foundation of long-term adherence. Trustpilot ratings and captured review themes (all captured September 4, 2026 unless noted) provide a rough signal:

  • PlexusDx: 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026).
  • MEDVi: 4.3 stars, approximately 15,000 reviews.
  • Henry Meds: 4.4 stars, approximately 13,000 reviews.
  • Eden: 4.5 stars, approximately 5,000 reviews; one captured 1-star review reports an 11-day order delay and repeated requests for medical records.
  • Found: 4.1 stars, 732 reviews.
  • Fridays Health: 4.2 stars, approximately 4,700 reviews.
  • OrderlyMeds: 3.6 stars, 634 reviews; captured complaints cite fast initial charging but slow refunds, non-response to support inquiries, delayed shipping, pharmacy changes without notice, and unwanted calls and texts after opt-out.

No rating or review set establishes causation or typical experience—individual reports are anecdotes, not guarantees. However, patterns of communication delays, order fulfillment issues, or refund disputes may signal operational stress. Readers prioritizing predictable fulfillment and responsive support should weigh rating volume and specific complaint themes alongside price.

Choose PlexusDx if…

  • You want month-to-month semaglutide injection at a flat $189 or tirzepatide injection at a flat $289, with the same price at every dose and no refill jump.
  • You prefer a single all-inclusive charge with no separate membership fee, no hidden visit charges, and no shipping fees.
  • You value the option to step down to microdose GLP-1 at $129/month during maintenance without switching providers.
  • You want the flexibility to cancel any month without forfeiting prepaid costs, while retaining access to discounted 3-month ($169 sema, $269 tirz) or 6-month ($149 sema, $249 tirz) plans if you later choose to lock in a lower rate.

Choose MEDVi if…

  • You can absorb the $179 introductory semaglutide month followed by $299 refills, yielding a $289 effective monthly cost over a year (our calculation), and the 4.3-star Trustpilot rating with approximately 15,000 reviews suggests adequate service consistency for your risk tolerance.
  • You prefer dose-agnostic pricing—MEDVi explicitly states dose increases do not raise the monthly cost.
  • You want month-to-month flexibility without a separate membership fee on the compounded medication path.

Choose Henry Meds if…

  • You specifically want semaglutide injection month-to-month at $297 and can accept that tirzepatide is available only as an oral dissolving tablet on a 3-month minimum commitment, not as an injection.
  • The 4.4-star Trustpilot rating (approximately 13,000 reviews) and established operational footprint outweigh the $108/year premium versus PlexusDx's $189 semaglutide rate (our calculation: $297 × 12 – $189 × 12 = $1,296 difference).
  • You value Henry Meds' sublingual semaglutide tablets at $249/month or liraglutide injection at $179/month as alternative GLP-1 pathways if standard semaglutide injection proves unsuitable.

Choose Eden if…

  • You prefer a two-component structure—$99/month medication plus $99/month membership (total $198 ongoing after a $39 introductory first-month membership discount)—and the separate billing aligns with your budgeting or insurance reimbursement workflow.
  • The 4.5-star Trustpilot rating (approximately 5,000 reviews) and the captured report of an 11-day delay with repeated record requests do not disqualify the program given the $2,316 effective 12-month cost (our calculation), which sits $48 above PlexusDx's $189 flat semaglutide rate annualized.
  • You want access to both injectable and oral routes, with final route determination made by the Eden clinician rather than locked at intake.

Choose Embody, Peak Wellness, TrimRx, Found, or Fridays Health if…

  • Their month-to-month semaglutide rates ($249–$299) and tirzepatide rates ($349–$399) fit your budget, and you have confirming evidence—via checkout or direct contact—that the advertised month-to-month figure holds at the payment step.
  • You prefer one of these providers' support models, pharmacy partnerships, or clinician networks over other options in this roundup, and the premium over PlexusDx's $189 semaglutide or $289 tirzepatide reflects features or service quality you value.
  • You prioritize a specific brand reputation or Trustpilot profile (where available) that aligns with your risk tolerance and service expectations.

Methodology and freshness

This comparison relies on pricing and policy data captured between September 4 and September 7, 2026, from provider checkout pages, public pricing pages, and Trustpilot profiles. PlexusDx pricing was verified September 7, 2026; MEDVi checkout verified September 4, 2026; Henry Meds, Eden, Found pricing pages verified September 4–7, 2026; Embody, Peak Wellness, TrimRx, Fridays Health checkout or pricing-page verification completed September 7, 2026. Trustpilot ratings captured September 4, 2026.

Effective monthly costs over 12 months, normalized totals, and percentage comparisons are our calculation, derived from the captured first-month and refill rates. Where pricing conflicts appear between advertised figures and checkout figures (e.g., TrimRx), we report both and advise readers to verify at the payment step. No provider guarantees eligibility, medication type, dose, or uninterrupted availability; a licensed clinician determines whether a prescription is appropriate in every case.

Frequently Asked Questions

Can I switch from a multi-month prepaid plan to month-to-month mid-cycle?

Most providers require you to complete the prepaid cycle before switching to month-to-month billing. If you cancel mid-cycle on a prepaid plan, you typically forfeit the remaining prepaid months. PlexusDx allows you to start month-to-month and later opt into 3-month or 6-month discounts when you're ready to commit, preserving flexibility early in treatment.

What happens if I need a dose increase on a flat-rate plan?

Providers offering dose-agnostic pricing—PlexusDx, MEDVi, and Embody among them—hold the same monthly rate regardless of dose, so a clinician-directed increase from 0.5 mg to 1 mg or higher carries no price change. Providers using per-dose pricing may raise your monthly cost when the clinician increases the dose; confirm the dose-pricing policy before starting treatment.

Do month-to-month plans include shipping and clinician visits?

All nine providers in this roundup bundle medication, clinician access, and shipping into the quoted monthly rate with no separate line-item charges. Eden's $99 membership fee is explicit and separate from the $99 medication charge, but both cover ongoing clinician support and shipping within their respective components.

Why does MEDVi charge a lower first-month rate than refill rate?

MEDVi's introductory semaglutide rate of $179 for the first month, followed by $299 refills, is a promotional pricing structure designed to lower the initial barrier to entry. The effective cost over 12 months is $289/month (our calculation). If you plan to stay on treatment for multiple months, the refill rate becomes the operative figure for budgeting.

Are compounded GLP-1 medications identical to Wegovy, Ozempic, Zepbound, or Mounjaro?

No. Compounded medications are not FDA-approved and are not identical to branded drugs. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. Compounded semaglutide and tirzepatide use the same active pharmaceutical ingredients as the branded versions, but formulation, concentration, delivery mechanism, and quality-control processes differ. A licensed clinician determines whether a compounded prescription is appropriate for you based on your individual medical history and treatment goals.

Sources

  • PlexusDx pricing and policy pages (captured 2026-09-07)
  • MEDVi checkout verification and pricing pages (captured 2026-09-04)
  • Henry Meds pricing and product pages (captured 2026-09-04)
  • Eden pricing page (captured 2026-09-04)
  • Embody checkout verification (captured 2026-09-07)
  • Peak Wellness checkout verification (captured 2026-09-07)
  • TrimRx checkout verification (captured 2026-09-07)
  • Found pricing page (captured 2026-09-07)
  • Fridays Health pricing page (captured 2026-09-07)
  • BrightMeds pricing page (captured 2026-09-04)
  • Trustpilot profiles for PlexusDx, MEDVi, Henry Meds, Eden, Found, Fridays Health, OrderlyMeds (captured 2026-09-04)

Ready to start month-to-month GLP-1 with no long-term commitment?

One all-inclusive price covers your online provider visit, prescription, medication, and shipping—no membership, no hidden fees. Complete a short intake and a licensed provider reviews your fit.

Start My Intake →

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

Real prescribers. Published prices. No surprises.

Licensed providers in all 50 states. Online intake. No insurance, no membership required.

Start My Intake

~60 seconds · $0 charged until your provider approves