Last reviewed: September 7, 2026
Last updated: September 7, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
10Rx charges $299 every three months for compounded semaglutide (a prepaid equivalent of $99.67/month) and $450 every three months for compounded tirzepatide ($150/month prepaid equivalent), making it one of the lowest-cost options by total annual spend—$1,196 and $1,800 respectively. That pricing requires quarterly prepayment and locks you into three-month cycles. If you want month-to-month flexibility with no upfront commitment, seven verified alternatives range from $189/month to $359/month for semaglutide and $249/month to $399/month for tirzepatide. PlexusDx charges $189/month for semaglutide injection and $289/month for tirzepatide injection, both month-to-month with no membership fee and the same price at every dose. Eden charges $198/month all-in for semaglutide and $298/month for tirzepatide once you add the required $99/month membership to the $99 medication-only headline. Peak Wellness, Embody, Found, Henry Meds, and TrimRx all charge $249–$359/month for semaglutide and $349–$399/month for tirzepatide on month-to-month billing. The choice turns on whether you value 10Rx's prepaid savings over the ability to pause, adjust, or cancel month by month without forfeiting a quarterly payment.
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At-a-glance: 10Rx vs. verified monthly alternatives
| Provider |
Semaglutide (monthly) |
Tirzepatide (monthly) |
Billing |
Membership |
| 10Rx |
$99.67 (prepaid equivalent) |
$150 (prepaid equivalent) |
Quarterly prepaid |
None |
| PlexusDx |
$189 |
$289 |
Month-to-month |
None |
| Eden |
$198 all-in |
$298 all-in |
Month-to-month |
$99/mo required |
| Peak Wellness |
$249 |
$349 |
Month-to-month |
None |
| Found |
$289 cash |
$359 cash |
Month-to-month |
None |
| Henry Meds |
$297 |
Oral only (not listed) |
Month-to-month |
None |
| TrimRx |
$299 ongoing |
$399 ongoing |
Month-to-month |
None |
| Embody |
$299 |
$349 |
Month-to-month |
None |
Sources: 10Rx primary website and secondary corroboration captured September 4, 2026; alternative provider pricing verified at checkout July 17–23, 2026. 10Rx prepaid-equivalent figures are our calculation based on quarterly totals divided by three.
Breaking down 10Rx pricing structure
10Rx charges $299 for a three-month supply of compounded semaglutide injection and $450 for a three-month supply of compounded tirzepatide injection, both with B12. The quarterly totals include medication, clinician evaluation, next-day shipping, and support, with no separate membership fees and the same package price across available dose strengths. Payment is due every three months. Dividing the quarterly total by three yields a prepaid-equivalent monthly rate of $99.67 for semaglutide and $150 for tirzepatide. Over twelve months, that works out to $1,196 for semaglutide and $1,800 for tirzepatide (our calculation). 10Rx's primary pricing page confirms the quarterly flat-strength structure and all inclusions but does not display numeric package totals on the main page; the $299 and $450 totals are documented through secondary corroboration captured September 4, 2026, and we state that evidence basis plainly. Cancellation and refund terms are not documented in available sources, so if you need to stop before a quarter ends, confirm the policy directly with 10Rx before your first payment.
Month-to-month alternatives: verified pricing and annual cost
Seven providers offer compounded semaglutide or tirzepatide on month-to-month billing with pricing verified at checkout between July 17 and July 23, 2026. We calculate twelve-month totals to compare apples-to-apples against 10Rx's quarterly prepaid model.
PlexusDx
Compounded semaglutide injection is $189/month month-to-month, for an annual cost of $2,268 (our calculation). Compounded tirzepatide injection is $289/month, totaling $3,468 over twelve months. PlexusDx charges no membership fee, maintains the same price at every dose, and lets you pause or cancel month by month. Longer commitments reduce the monthly rate: $169/month for semaglutide and $269/month for tirzepatide on a three-month plan, or $149/month semaglutide and $249/month tirzepatide on a six-month plan. PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026).
Eden
Eden advertises $99 for medication, but that figure excludes the required $99/month membership. The all-in monthly cost is $198 for semaglutide and $298 for tirzepatide, translating to $2,376 and $3,576 annually (our calculation). Pricing verified at checkout July 17–23, 2026.
Peak Wellness
Peak Wellness charges $249/month for semaglutide injection and $349/month for tirzepatide injection on month-to-month billing, with no separate membership. Over twelve months, that totals $2,988 for semaglutide and $4,188 for tirzepatide (our calculation). Peak Wellness also offers lower per-month rates on six-month prepaid plans. Pricing verified July 17–23, 2026.
Henry Meds
Henry Meds charges $297/month for compounded semaglutide injection, totaling $3,564 over twelve months (our calculation). Henry Meds offers tirzepatide as an oral dissolving tablet only, not an injection, and no monthly injection rate is published. One monthly subscription covers medication, shipping, and provider access with no separate membership fee. Pricing verified July 17–23, 2026.
TrimRx
TrimRx advertises $199 for semaglutide and $349 for tirzepatide, but checkout-verified ongoing rates are $299/month for semaglutide and $399/month for tirzepatide. Annual totals are $3,588 for semaglutide and $4,788 for tirzepatide (our calculation). TrimRx offers lower per-month rates on three-, six-, and twelve-month plans charged upfront. Pricing verified July 17–23, 2026.
Embody
Embody charges $299/month for compounded semaglutide and $349/month for compounded tirzepatide, with no membership fee and the same price at every dose. Twelve-month totals are $3,588 for semaglutide and $4,188 for tirzepatide (our calculation). Pricing verified July 17–23, 2026.
Found
Found's cash-pay monthly plan charges $289/month for semaglutide and $359/month for tirzepatide, totaling $3,468 and $4,308 over twelve months (our calculation). Found also advertises "from $169/mo," which is the per-month equivalent of a twelve-month plan paid upfront, not a month-to-month rate. Pricing verified July 17–23, 2026.
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Prepaid savings vs. monthly flexibility
10Rx's quarterly prepaid model delivers the lowest total annual cost in this comparison: $1,196 for semaglutide and $1,800 for tirzepatide, compared to $2,268–$3,588 annually for semaglutide and $2,988–$4,788 annually for tirzepatide across the seven month-to-month alternatives. That advantage comes at the cost of quarterly commitment. If you need to pause treatment, change medications, or stop altogether before the three months end, you forfeit flexibility unless 10Rx offers a prorated refund—and no refund policy is documented in available sources. Month-to-month billing lets you pause or cancel without losing a prepaid quarter, but you pay a premium for that flexibility. PlexusDx, Eden, and Peak Wellness charge $189–$249/month for semaglutide and $289–$349/month for tirzepatide, roughly double 10Rx's prepaid-equivalent rate but with the ability to adjust or stop each month. If you're confident you'll stay on the same medication for at least three months and want the lowest cost, 10Rx's prepaid structure wins. If you want the option to pause, switch, or cancel month by month, a higher-priced monthly alternative offers that control.
Same-price-every-dose policies
10Rx charges the same quarterly package price across available semaglutide and tirzepatide strengths. PlexusDx, Embody, Peak Wellness, Henry Meds, and TrimRx all state the same price at every dose on their respective platforms. Eden's all-in rate includes a membership that covers access regardless of dose. Found's cash-pay plan likewise quotes a single monthly rate per medication. If you anticipate titrating up to maintenance doses, same-price policies mean no surprise increases as your prescription strength rises—but confirm dose availability and titration protocols with each provider, because not every platform stocks every strength.
Trustpilot and review context
No Trustpilot profile was located for 10Rx as of September 4, 2026. PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026). Review ratings for the other alternatives are not documented in available sources. If service quality, support responsiveness, or track record matter to you, search the provider's name on Trustpilot, Reddit, or Google to see what current and former patients report, and weigh that feedback alongside pricing and billing structure.
Choose 10Rx if…
- You want the lowest total annual cost and are comfortable committing to three-month cycles.
- You have high confidence you will stay on the same medication for at least a full quarter.
- Quarterly prepayment fits your budget and you do not need the flexibility to pause or cancel month by month.
- You prefer a flat package price across dose strengths with no separate membership fee.
Choose a month-to-month alternative if…
- You value the ability to pause, adjust, or cancel without forfeiting a prepaid quarter.
- You are still titrating doses or trying different GLP-1 medications and want flexibility to switch.
- You prefer to pay monthly rather than committing to a larger quarterly payment upfront.
- You want access to a provider with documented Trustpilot reviews or a longer service track record.
Where PlexusDx fits
PlexusDx charges $189/month for compounded semaglutide injection and $289/month for compounded tirzepatide injection, both month-to-month with no membership fee and the same price at every dose. That is roughly double 10Rx's prepaid-equivalent rate, but you can pause or cancel month by month without losing a quarterly payment. If you want month-to-month flexibility at a mid-tier price point—lower than Found, Henry Meds, TrimRx, and Embody, and competitive with Eden once you add Eden's required membership—PlexusDx offers a straightforward alternative. PlexusDx also offers three-month and six-month commitment discounts ($169/month and $149/month for semaglutide, $269/month and $249/month for tirzepatide), oral semaglutide and tirzepatide capsules, and a microdose semaglutide injection protocol at $129/month for maintenance. A licensed provider reviews your intake to determine whether a prescription is appropriate for your individual situation.
Methodology and freshness
10Rx commercial facts (quarterly prepaid packages, inclusions, flat-strength pricing, no membership fee) are drawn from the provider's primary pricing page and secondary corroboration, both captured September 4, 2026. The primary page verifies structure and inclusions but does not display numeric package totals; the $299 semaglutide and $450 tirzepatide quarterly totals are documented through secondary corroboration, and we state that mixed-evidence basis plainly. Alternative provider pricing (PlexusDx, Eden, Embody, Found, Henry Meds, Peak Wellness, TrimRx) was verified at checkout between July 17 and July 23, 2026. PlexusDx Trustpilot rating (4.3 stars, 79% five-star, 83% four-star or higher) was captured September 9, 2026. All twelve-month cost totals and prepaid-equivalent monthly rates are our calculation, derived by multiplying or dividing the verified per-period figures. Prices, inclusions, dose availability, and cancellation policies may change; confirm current terms at checkout before committing.
Frequently Asked Questions
Is 10Rx's quarterly prepaid price the same for every semaglutide dose?
Yes. 10Rx charges $299 for a three-month supply of compounded semaglutide across available strengths, and $450 for a three-month supply of compounded tirzepatide, with the same package price regardless of dose. Confirm dose availability and titration protocols directly with 10Rx if you anticipate moving to higher maintenance strengths.
Can I cancel 10Rx before the three months end and get a prorated refund?
Cancellation and refund terms are not documented in available sources. If you need the option to stop or pause mid-quarter, ask 10Rx about their refund policy before your first payment, or choose a month-to-month alternative that lets you cancel without forfeiting a prepaid quarter.
Does PlexusDx charge a membership fee on top of the monthly medication price?
No. PlexusDx charges $189/month for compounded semaglutide injection and $289/month for compounded tirzepatide injection, both month-to-month with no separate membership fee. The monthly rate includes medication, provider visit, and shipping.
Why is Eden's all-in cost $198/month when it advertises $99?
Eden's $99 figure is for medication only and requires a separate $99/month membership, bringing the total to $198/month for semaglutide or $298/month for tirzepatide. The advertised $99 headline excludes the membership fee, so confirm the all-in cost at checkout.
Which provider offers the lowest twelve-month total cost for semaglutide?
10Rx offers the lowest twelve-month cost at $1,196 for semaglutide (our calculation, based on $299 quarterly total). Among month-to-month alternatives, PlexusDx is lowest at $2,268 annually for semaglutide injection, followed by Eden at $2,376 and Peak Wellness at $2,988.
Sources
- PlexusDx pricing and Trustpilot rating, captured September 4–7, 2026
- 10Rx primary pricing page, captured September 4, 2026
- 10Rx secondary pricing corroboration, captured September 4, 2026
- Eden, Embody, Found, Henry Meds, Peak Wellness, TrimRx checkout-verified pricing, captured July 17–23, 2026
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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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