WHAT CHANGES FOR YOU

How GLP-1 weight loss works

Real prescription medicine. A licensed provider sets every dose.

THE SCIENCE

Start low, on your terms

Semaglutide or tirzepatide at a lower dose, as a weekly shot or daily tablet. Both act like GLP-1, the gut hormone that tells your brain you've had enough.

THE GOAL

Show up to your day differently

You want clothes that fit, food back in its place, and to feel like yourself again.

HOW LONG IT TAKES

Real change takes a little time

Your provider starts you low and adjusts your dose as you go. You're never doing this alone.

YOUR GENETICS

See what your DNA says

The optional GLP-1 & Peptide Pathways Genetic Test gives you 34 weight management insights to share with your provider.

READY?

A plan your provider designs around you.

Start your intake

A short online visit · Cards are charged once your prescription is sent to the pharmacy.

Overview

Compounded Microdose GLP-1 is PlexusDx's entry-level weight management program: lower doses of semaglutide or tirzepatide, as a weekly injection or a daily tablet, prescribed by licensed clinicians. Each variant contains semaglutide, the active ingredient in Wegovy® and Ozempic® (Novo Nordisk), or tirzepatide, the active ingredient in Zepbound® and Mounjaro® (Eli Lilly), at low-dose strengths selected clinically by your provider. One price per plan covers your provider visit, prescription, medication, and shipping: $69 to $99 a month by plan length, from $69/mo on a 12-month plan ($828 billed up front) to $99 month to month. Same price whichever microdose you choose. No membership fee.

  • You choose semaglutide or tirzepatide, as a weekly injection or a daily tablet; your provider makes the final decision
  • Low-dose GLP-1 mechanism — semaglutide acts on the GLP-1 receptor; tirzepatide acts on the GIP and GLP-1 receptors
  • 1-, 3-, 6- or 12-month plans at $99, $89, $79 or $69 a month — 3-, 6- and 12-month plans are charged once, up front, and renew automatically
  • Real medical authority — U.S.-licensed clinicians, no AI prescriptions
  • 34 Weight Management genetic insights including FTO rs9939609 — optional GLP-1 & Peptide Pathways Genetic Test, $99 as an add-on after your first month

The optional GLP-1 & Peptide Pathways Genetic Test analyzes 34 Weight Management insights including FTO rs9939609, a variant in a gene involved in hunger and energy balance, drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

Why trust PlexusDx

Compliance

503A pharmacy-grade medication

Your compounded Microdose GLP-1 is prepared by a licensed 503A compounding pharmacy for your prescription — not mass-manufactured.

Coverage

Licensed providers across the U.S.

Your provider confirms availability in your state at your visit.

Privacy

HIPAA-compliant platform

Protected under HIPAA. Never sold or shared without your consent. Manage your plan in your patient portal at my.plexusdx.com.

Pricing

Transparent pricing

Same price whichever microdose you choose.

Pricing

What Microdose GLP-1 costs

Same price whichever microdose you choose.

Starts at $69/mo

·

12-month plan, $828 billed up front · $99 month to month

No membership fee.

Plan lengths

  • $99/mo 1-month plan Billed monthly
  • $89/mo 3-month plan $267 billed up front
  • $79/mo 6-month plan $474 billed up front
  • Best value $69/mo 12-month plan $828 billed up front Includes a provider check-in at 6 months

3-, 6- and 12-month plans are charged once, up front, and renew automatically. Cancel future renewals anytime.

HSA and FSA cards accepted at checkout · Pay over time on 3-, 6- and 12-month plans

Online visit with a licensed provider Prescription, if appropriate Compounded Microdose GLP-1 Shipping included

Provider-determined dosing

You choose semaglutide or tirzepatide, as a weekly shot or a daily tablet, on the intake's medication step. Your provider reviews your choice and makes the final decision, then adjusts your plan over time.

Start your online visit

Cards are charged once your prescription is sent to the pharmacy.

A short online visit. A licensed provider decides whether a prescription is right for you.

WHAT HAPPENS NEXT

After you order

What happens once your intake is in.

After your visit

LICENSED REVIEW

Provider review & prescription

A licensed U.S. provider reviews your online visit and decides whether a prescription is right for you.

Once prescribed

503A COMPOUNDING

Pharmacy ships your medication

Your compounded Microdose peptide ships from a US 503A pharmacy in discreet packaging. A 503A pharmacy is a state-licensed compounding facility regulated by FDA and state boards of pharmacy that prepares medications individually for a specific patient based on a valid prescription. Dosing schedule included

Ongoing

CARE THAT CONTINUES

Ongoing provider care

Your provider follows your progress and adjusts your treatment when appropriate.

Anytime

FLEXIBILITY

Manage your plan

Manage your plan in your patient portal at my.plexusdx.com. Cancel future renewals anytime.

OUR COMMITMENT

Cards are charged once your prescription is sent to the pharmacy. Cancel future renewals anytime.

YOUR PLAN

What's included

Your provider, your pharmacy, your direct-to-door shipping — everything in your Microdose GLP-1 plan.

PROVIDER

Licensed, online

Licensed providers across the U.S.

PHARMACY

503A compounded

Compounded Microdose GLP-1 prepared to your provider's prescription.

SHIPPING

Direct-to-door

Discreet packaging. Ships from U.S. partner pharmacy.

PLAN PRICING

One price per plan

Your plan price covers your provider, prescription, medication and shipping. No membership fee.

WHAT YOU WON'T PAY
Membership fee
Consult charge
Hidden fees
REFILLS

Provider-reviewed

Your plan renews automatically. 1-month plans ship a 1-month supply; longer plans ship a 3-month supply in each box.

MONITORING

Provider check-ins

Your provider follows your progress and adjusts your dose when appropriate.

FLEXIBILITY

Manage your plan

Manage your plan in your patient portal. Cancel future renewals anytime.

Optional add-on
Available post-enrollment

The optional GLP-1 & Peptide Pathways Genetic Test analyzes 34 Weight Management insights including FTO rs9939609 — a variant in a gene involved in hunger and energy balance — drawn from a 150+ insight panel across 14 pathways. Available for $99 as an add-on after your first month of treatment.

34
Pathway insights
150+
Total panel
14
Pathways
$99
Add-on
Featured SNP
FTO rs9939609
a variant in a gene involved in hunger and energy balance

CLINICAL FIT CHECK

Is this protocol right for you?

We lead with safety considerations first. If any exclusion applies to you, stop here and speak with your primary care provider before starting intake.

SAFETY EXCLUSIONS

Skip this protocol if…

THYROID HISTORY

Personal or family history of medullary thyroid carcinoma (MTC) or MEN2

PANCREATITIS

Any history of pancreatitis

PREGNANCY STATUS

Pregnant, breastfeeding, or planning pregnancy

CONCURRENT GLP-1

Currently taking another GLP-1 or GIP/GLP-1 medication

ELIGIBLE

You're a fit if…

BMI THRESHOLD

BMI ≥27 with a weight-related condition, or BMI ≥30

CLINICAL OVERSIGHT

Want oversight from a U.S.-licensed provider

PRICING TRANSPARENCY

Want every price published up front

DATA-GUIDED CARE

You prefer clinical decisions informed by your personal health data

PROVIDER VERDICT

Your licensed provider confirms final eligibility during intake review. No medication ships without their sign-off.

Built differently

What makes PlexusDx different

Five things every shopper deserves before they sign up.

THE DIFFERENTIATOR

Genetics-informed care from a complete precision health platform

34 Weight Management insights via the GLP-1 & Peptide Pathways Genetic Test — across 14 pathways, 49 peptides. The only telehealth peptide protocol with a genetic testing layer.

TRANSPARENCY

Radically transparent

Every plan and every price published.

PRICING

One plan price

One price for intake, Rx, medication, shipping.

CLINICAL

Online clinical oversight

No in-person visits. A short online visit with a licensed provider.

NO GATE

No membership gate

Your first dollar goes toward care, not a membership fee.

Clinical details

Clinical details

How this compound works and what lab work is involved.

Compound spec

Class

GLP-1 agonist

semaglutide or tirzepatide


Route

Tablet or injection

you choose, your provider confirms


Half-life

~7 days

varies by variant


Compounded by

503A pharmacy

licensed US partner

How it works

About this compound

Microdose GLP-1 starts with lower doses of semaglutide or tirzepatide, as a weekly injection or a daily tablet. Semaglutide acts on the GLP-1 receptor; tirzepatide acts on both the GIP and GLP-1 receptors.

You choose your option on the intake's medication step, and your provider makes the final decision and supervises your treatment.

See how PlexusDx customers describe their precision health journey — read Customer Stories.

Why it matters

The optional GLP-1 & Peptide Pathways Genetic Test analyzes 34 Weight Management insights including FTO rs9939609, a variant in a gene involved in hunger and energy balance. Available for $99 as an add-on after your first month of treatment.

Lab requirements
No blood work required at intake. Blood testing is available at patient election and may be recommended by your provider based on your individual health history.
NOT REQUIRED
Compare Compounds

How this compound compares

Compound
Mechanism
Route
Monthly price
Semaglutide Injection
GLP-1 agonist
Subcutaneous injection
$99/mo (12-mo plan) · $149 month to month
Tirzepatide Injection
GIP/GLP-1 dual agonist
Subcutaneous injection
$129/mo (12-mo plan) · $189 month to month
Semaglutide Oral
GLP-1 agonist
Daily dissolving tablet
$99/mo (12-mo plan) · $149 month to month
Tirzepatide Oral
GIP/GLP-1 dual agonist
Daily dissolving tablet
$129/mo (12-mo plan) · $189 month to month
You're viewingMicrodose GLP-1
Low-dose GLP-1 agonist
Tablet or injection
$69/mo (12-mo plan) · $99 month to month

Microdose GLP-1 Protocol — FAQ

Answers before you start

Pricing, titration, genetics, and what happens if you need a different dose or compound — directly answered, no hedging.

PRICING

How much does Microdose GLP-1 cost?

Microdose GLP-1 starts at $69/mo on a 12-month plan ($828 billed up front). Or $79/mo for 6 months ($474), $89/mo for 3 months ($267), or $99 month to month. 3-, 6- and 12-month plans are charged once, up front, and renew automatically. Cancel future renewals anytime. No membership fee. Same price whichever microdose you choose.

INCLUSIONS

What's included in every plan?

Every Microdose GLP-1 plan includes your online visit with a licensed provider, your prescription, your compounded microdose medication, and shipping to your door. There is no membership fee and no consult charge. Same price whichever microdose you choose. Cancel future renewals anytime.

VARIANT SELECTION

How is my microdose option chosen?

You choose semaglutide or tirzepatide, as a weekly injection or a daily tablet, on the intake's medication step. Your provider reviews your health history and your choice, and makes the final decision. Your price is the same whichever microdose you choose; it changes only with your plan length.

MECHANISM

What is microdosing and how does Microdose GLP-1 work?

Microdose GLP-1 starts with lower doses of semaglutide or tirzepatide, as a weekly injection or a daily tablet. Semaglutide acts on the GLP-1 receptor; tirzepatide acts on both the GIP and GLP-1 receptors. You choose your option in the intake, and your provider makes the final decision.

GENETICS

Do I need my GLP-1 & Peptide Pathways Genetic Test before starting?

No. You can start Microdose GLP-1 first. The optional GLP-1 & Peptide Pathways Genetic Test is a $99 add-on after your first month. It analyzes 150+ insights across 14 pathways, including 34 Weight Management insights such as FTO rs9939609. It reports on your biology. It does not determine which medication you use; your provider does.

FLEXIBILITY

What if I need a different variant or a full-dose protocol?

Your provider can adjust your dose over time, and your price stays the same whichever microdose you choose. If your provider recommends a different medication, such as full-dose semaglutide or tirzepatide, unused prepaid value is credited toward it and you pay only the difference. Cancel future renewals anytime.

RESEARCH

Is there a study on microdosing tirzepatide?

Yes. PlexusDx looked back at its own patients who started the tirzepatide injection at 1 to 2 mg a week and published what it saw, with every limit stated. It was not a clinical trial, and it cannot prove the medicine caused the change. Read the microdose tirzepatide study page.

PAYMENT

Can I use my HSA or FSA card, or pay over time?

Yes. HSA and FSA cards are accepted at checkout. Eligibility depends on your HSA or FSA plan, so check with your plan administrator. On 3-, 6- and 12-month plans you can also pay over time: pay-later options show at checkout when you're eligible. Pay over time isn't offered on 1-month plans.

DELIVERY

Can I pause or change my deliveries?

Yes. Pause a delivery or update your shipping address in your patient portal at my.plexusdx.com.

─── READY TO START

Start your Microdose GLP-1 protocol today

Three reasons to start with PlexusDx.

ENROLL TODAY
Ready to Start Your Microdose GLP-1 Protocol?

Order your Microdose GLP-1 protocol today. Gain access to 34 Weight Management genetic insights post-enrollment, including FTO rs9939609. Make informed decisions supported by clinical oversight and your unique biology.

Start Today →
Short online visit · Choose Microdose GLP-1 on the medication step
TRANSPARENCY
Every plan, every price
Published before you enroll. No intake required.
Radically transparent
PLAN PRICING
One price per plan
Online visit, prescription, medication and shipping: one price per plan.
No surprise billing
GENETICS-INFORMED
Your biology, your care
150+ insights across 14 pathways, available post-enrollment for $99.
The only telehealth layer
Important Information
Compounded medications are not approved by the FDA or reviewed for quality, safety, or efficacy.

Novo Nordisk, Inc. is the only United States company with FDA-approved products containing semaglutide, identified under the trade names Rybelsus®, Ozempic®, and Wegovy®.

Lilly USA LLC is the only United States company with FDA-approved products containing tirzepatide, identified under the trade names Zepbound® and Mounjaro®.

The GLP-1 & Peptide Pathways Genetic Test analyzes how your genes influence peptide-related biological pathways. It does not recommend, prescribe, or determine which peptides you should use. Consult a qualified healthcare provider before beginning any peptide protocol.