TrimRx vs PlexusDx: pricing chart, semaglutide and tirzepatide (2026)
PlexusDx costs less than TrimRx's checkout price at every plan length: semaglutide is $149 a month vs TrimRx's $179 first month, then $299. PlexusDx also offers a free 15-minute PharmD consult and sells genetic and blood tests separately.
TrimRx reviews: 3.7/5 on Trustpilot (5,367 reviews) · F from the BBB
| Checkout price | PlexusDx | TrimRx |
|---|---|---|
| Semaglutide month to month | $149/mo | $179 first month, then $299/mo |
| Semaglutide 12-month plan | $99/mo $1,188 up front | $174/mo prepaid |
| Tirzepatide month to month | $189/mo | $279 first month, then $399/mo |
| Tirzepatide 12-month plan | $129/mo $1,548 up front | $283/mo prepaid |
- When you're charged
- PlexusDx: When your prescription goes to the pharmacy
- TrimRx: Only if your prescription is approved
- Refunds
- PlexusDx: Full refund until it reaches the pharmacy
- TrimRx: Refunded if not prescribed; unused prepaid months within 28 days of paying
- Shipping
- PlexusDx: Free, UPS 2nd Day Air
- TrimRx: Free; ships in about 2 business days
- Same at both
- Support 7 days a week · No membership fee
What else PlexusDx offers
GLP-1 & Peptide Pathways Genetic Test
150+ genetic insights across 14 health pathways.
$298, or $99 for program members.
See the test →At-home blood tests from $129
Plus supplement packs from $79, built from your results.
See blood tests →The GLP-1 & Peptide Pathways Genetic Test does not select or predict a medication; your provider decides.
What do TrimRx's reviews say?
TrimRx's reviews split by platform: 62% of its Trustpilot reviews give five stars and 29% give one, and the BBB rates it F.
Trustpilot
62% five-star · 29% one-star
- Replies to 93% of negative reviews, usually within a week.
- Asks customers to review.
- Most-mentioned topics include customer communications, orders, delivery and cancellation.
BBB
F, not accredited
- 2,606 complaints in the past 12 months; the BBB cites 783 with no response from the business.
- The BBB shows a "Pattern of Complaints" alert and opened an investigation in March 2026.
- Most complaints on its first page are product issues.
Both read at source on Oct 20, 2026. Ratings belong to the platforms, not to PlexusDx.
What do TrimRx and PlexusDx cost on 3- and 6-month plans?
PlexusDx costs less on 3- and 6-month plans too: semaglutide is $129 and $109 a month against TrimRx's $209 and $191.
| Plan | PlexusDx | TrimRx |
|---|---|---|
| Semaglutide 3-month plan | $129/mo $387 up front | $209/mo |
| Semaglutide 6-month plan | $109/mo $654 up front | $191/mo |
| Tirzepatide 3-month plan | $169/mo $507 up front | $316/mo |
| Tirzepatide 6-month plan | $149/mo $894 up front | $299/mo |
Is TrimRx or PlexusDx better?
PlexusDx is better on price at every plan length; TrimRx is better if you may want unused prepaid months refunded.
Choose TrimRx if…
- You want unused prepaid months refundable if you ask within 28 days of paying.
Choose PlexusDx if…
- You want the lower price at every plan length.
- You want the same monthly price from the first month on.
- You want a free 15-minute consult with Dr. Jayden Lee, PharmD, by video or phone.
- You want at-home blood tests, sold separately.
How do TrimRx and PlexusDx compare on cancelling and formats?
Both let you stop future orders before they are filled.
Read on Oct 20, 2026 from each company's own pages.
- Cancelling
- PlexusDx: Turn off renewal in your patient portal before the next charge
- TrimRx: Through your account or support; applies to future unfilled orders
- Formats
- PlexusDx: Injection, including a microdose program
- TrimRx: Injection in the sign-up we walked on Oct 20, 2026
- Same at both
- Pay over time on 3-, 6- and 12-month plans · HSA and FSA cards · Same price at every dose · LegitScript seal
How does compounded GLP-1 telehealth work?
You complete an online intake, a licensed provider reviews it, and if treatment is appropriate a state-licensed 503A pharmacy prepares and ships your medication, with no in-person visit.
Both PlexusDx and TrimRx start with an online intake and a licensed U.S. provider's review. In the PlexusDx program, a 503A compounding pharmacy, a state-licensed facility that prepares medication for one patient from a valid prescription, fills the prescription and ships it to your door.
Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, quality, or effectiveness. They are a legal, provider-prescribed option prepared by a licensed pharmacy, not a generic or a substitute the FDA has evaluated.
How did we check these prices and reviews?
We walked TrimRx's sign-up to its payment page on Oct 20, 2026, without paying, and read its Terms, Trustpilot and BBB pages the same day.
We recorded every plan length for both drugs. The tables show each company's checkout price. TrimRx's monthly checkout price is for the first month and its regular monthly price follows; for 3-, 6- and 12-month plans its checkout showed a price per month, not a total. PlexusDx prices come from our product pages on the same day.
Who wrote this. The PlexusDx editorial team wrote this page, and Dr. Jayden Lee, PharmD, reviewed it for accuracy.
Our bias. PlexusDx publishes this page and is one of the two programs compared. We show where TrimRx is ahead, and we update the page when either company changes its prices.
Start with a free consult or an online visit
PlexusDx semaglutide is $149 month to month or $99/mo on a 12-month plan; tirzepatide is $189 or $129/mo.
A licensed provider reviews your intake before anything is prescribed.
Start your online visitOr book a free 15-minute consult with Dr. Jayden Lee, PharmDFrequently Asked Questions
How much does TrimRx cost per month?
TrimRx's checkout price for semaglutide is $179 for the first month, then $299 a month; tirzepatide is $279, then $399. Checked Oct 20, 2026; the pricing chart below lists every plan.
What is TrimRx's pricing chart?
Month to month, TrimRx is $179 for the first month and then $299 for semaglutide, or $279 and then $399 for tirzepatide. On 3-, 6- and 12-month plans its checkout shows $209, $191 and $174 a month for semaglutide and $316, $299 and $283 for tirzepatide. PlexusDx is $149, $129, $109 and $99 a month for semaglutide and $189, $169, $149 and $129 for tirzepatide.
Is TrimRx cheaper than PlexusDx?
No. PlexusDx costs less than TrimRx's checkout price at every plan length. Semaglutide is $149 a month at PlexusDx against TrimRx's $179 first month and $299 after; on 12 months it is $99 against $174 a month.
Does TrimRx charge a membership fee?
No. Neither TrimRx nor PlexusDx charges a membership fee.
Does TrimRx's price go up with dose?
No. TrimRx says "Same Price. All Dosage Levels." PlexusDx works the same way: your dose may need to go up; your price won't.
When does TrimRx charge your card?
Only if your prescription is approved, according to its checkout. TrimRx's checkout says "Only charged if your prescription is approved."
Can you get a refund from TrimRx?
Yes, in some cases. TrimRx's checkout says orders are "100% refunded if not prescribed", and its Terms refund unused prepaid months if you ask within 28 days of paying; nothing is refunded once a prescription is processed or shipped. PlexusDx gives a full refund if you cancel after approval and before your prescription is sent to the pharmacy.
Is TrimRx legit?
TrimRx is an operating telehealth company whose reviews split by platform. As of Oct 20, 2026, Trustpilot rated it 3.7 out of 5 ("Average") across 5,367 reviews, while the BBB rated it F and not accredited, with 2,606 complaints in the past 12 months and a "Pattern of Complaints" alert. TrimRx is operated by Metafit Pharma Solutions, Inc. and shows a LegitScript seal in its footer.
Can I pay for TrimRx over time?
Yes. TrimRx offers 0% installments through Affirm, Klarna, Afterpay or PayPal on multi-month plans. PlexusDx also offers pay over time on 3-, 6- and 12-month plans.
Can I talk to a pharmacist?
Yes. PlexusDx offers a free 15-minute consult with Dr. Jayden Lee, PharmD, by video or phone. It is education and support; a licensed provider makes any prescribing decision.
What does the PlexusDx genetic test do?
The GLP-1 & Peptide Pathways Genetic Test shows how your genes relate to weight management and other peptide-related pathways, with 150+ genetic insights across 14 health pathways from one swab. It does not select or predict a medication; your provider decides. It costs $298, or $99 for program members, and is sold separately from any GLP-1 plan.
PlexusDx tells you about your biology. It does not tell you what to put in your body.
