Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

Part of the PlexusDx Education Hub, our plain-language library on GLP-1 programs, weight management, and the genetics behind metabolic decisions. Browse all Peptides & GLP-1 education

Independent editorial review. PlexusDx has no commercial relationship with Zealthy or its parent company, and this page includes no affiliate links or compensation.

Rather than zoom in on a single compound, this overview steps back to look at Zealthy's GLP-1 offering as a whole — what the program includes, who qualifies, and how the pieces fit together. Treating it as a category example clarifies how GLP-1 telehealth generally works, as of April 2026, without singling out one medication.

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What a GLP-1 telehealth program offers

Zealthy runs as subscription telehealth built around GLP-1 therapy. The core offering typically bundles a virtual clinical evaluation, a prescription routed to the appropriate pharmacy, and ongoing follow-up. It is a delivery model as much as a medication source: the value proposition is convenience and continuity of care, with the compound itself supplied through established pharmacy pathways.

Eligibility and the intake gate

Access starts with intake. A prospective patient submits weight, medical history, and a medication list, which a licensed clinician reviews against eligibility criteria before any prescription is issued. This gate is the point where a legitimate program screens for contraindications and suitability — not everyone who applies proceeds, and the review is meant to be a genuine clinical checkpoint rather than a formality.

Which GLP-1 compounds are in play

The category spans GLP-1 receptor agonists such as semaglutide, liraglutide, and dulaglutide, and the GIP/GLP-1 dual agonist tirzepatide. A program may dispense FDA-approved brand products through retail pharmacies or compounded semaglutide or tirzepatide through 503A pharmacies. Retatrutide, a triple agonist, is investigational and not FDA-approved. Which compounds a specific plan covers is detailed on Zealthy's official website.

The evidence base across GLP-1 therapies

The category's credibility rests on its trials. STEP studied semaglutide for weight management (published in The New England Journal of Medicine, 2021), SURMOUNT studied tirzepatide for weight management (NEJM, 2022), and SURMOUNT-OSA covered obstructive sleep apnea (NEJM, 2024). Populations and endpoints differ across programs, and individual outcomes vary — the evidence frames what these therapies can do on average.

Pricing across the GLP-1 telehealth market

Pricing varies by compound, subscription tier, and brand-versus-compounded dispensing. Typical monthly totals across the market as of April 2026 fall between roughly $200 and $700+, with wide variance; confirm current numbers on the brand's own site. For a transparent point of reference, PlexusDx prices its Semaglutide Injection at $189 per month, its Tirzepatide Injection at $289 per month, and a flat microdose option at $129 per month, with its genetic test at $298.

The upstream genetic variable

Every program in this category prescribes into a metabolic system genetics has already shaped. FTO influences appetite and adiposity set-point; GLP1R encodes the receptor GLP-1 compounds target; MC4R governs energy balance; and TCF7L2 ties into glucose homeostasis and GLP-1 secretion. These pathway-level variants do not predict response to any compound, but they describe the terrain a clinician prescribes into.

PlexusDx offers semaglutide and tirzepatide through its Weight Management Protocols, paired with the Precision Peptide Genetic Test, which analyzes 14 pathways, 49 peptides, 150+ genetic insights — including FTO, MC4R, and TCF7L2. That upstream context is what most GLP-1 telehealth programs do not offer alongside the medication.

Not affiliated: PlexusDx has no partnership or commercial tie to Zealthy; this overview is editorial only.

Related reading on PlexusDx: GLP-1 Drugs, GLP-1 Hormone, and What Is GLP-1.

Editorial note: educational only. PlexusDx is not affiliated with Zealthy and offers semaglutide and tirzepatide through its own protocols. The Precision Peptide Genetic Test analyzes how genes influence peptide-related pathways and does not predict response to any specific medication. Consult a qualified provider before beginning any protocol.

See how the approaches differ: explore the Weight Management Protocols, or take the Precision Peptide Genetic Test.

Frequently Asked Questions

What GLP-1 medications does a telehealth program prescribe?

Programs in this category typically work with semaglutide and tirzepatide, dispensed as FDA-approved brand products through retail pharmacies or as compounded preparations through 503A pharmacies. Other GLP-1 agents exist within the class, but the specific compounds a plan offers are listed on the brand's own website.

How do I know if I'm eligible for a GLP-1 program?

Eligibility is determined during intake, when a licensed clinician reviews your weight, medical history, and medications against program criteria. Certain conditions and histories are contraindications. The review is meant to screen for suitability before any prescription, so approval is not automatic on submitting an application.

How much do GLP-1 telehealth programs cost?

Monthly totals across the market typically range from roughly $200 to $700+ as of April 2026, depending on compound, tier, and dispensing pathway, with wide variance. Prices change frequently, so verify current figures on the brand's own site before committing to any subscription.

Does the genetic test replace a GLP-1 program?

No. The Precision Peptide Genetic Test does not prescribe or replace clinical care, and it does not predict response to any compound. It reads pathway-level variants in FTO and MC4R, and TCF7L2 to add upstream context before a provider conversation about a GLP-1 protocol.

Keep exploring the PlexusDx Education Hub. Browse all Peptides & GLP-1 education

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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