NAD Benefits: Biomarker Context and Provider-Guided Evaluation
NAD+ is a coenzyme involved in cellular energy and repair processes. Clinical research suggests potential benefits in mitochondrial function and metabolic health, though individual response varies significantly based on age, baseline biomarkers, and genetic factors.
What Is the Longevity-Aging Pathway in Genetic Testing?
The Longevity-Aging pathway in the Precision Peptide Genetic Test delivers 17 insights organized across five functional clusters — antioxidant defense, NAD+ homeostasis, methylation, longevity transcription factors, and structural aging biology. Part of 14 pathways, 49 peptides, and 150+ genetic insights, these 17 variants map biological aging as a connected system, not a list of isolated risk genes.
Can I Increase NAD+ Based on My Genetics? What the Evidence Shows
Yes — but how much NAD+ you can raise, through which pathway, and where your biggest genetic leak is all depend on your DNA. The Precision Peptide Genetic Test analyzes NAD+ pathway genetics across 14 pathways, 49 peptides, and 150+ genetic insights, revealing whether your rate-limiting step is synthesis, salvage, or overconsumption.
Does FOXO3 Affect How You Age? What the Science Shows
Yes — FOXO3 is one of the most replicated longevity genes in human genetics, and rs2802292 is the variant that explains why. The Precision Peptide Genetic Test analyzes FOXO3 alongside 14 pathways, 49 peptides, and 150+ genetic insights, revealing how your transcription factor genetics shapes oxidative stress resistance, DNA repair, and cellular lifespan.
Mitochondrial Function and Genetics: The Cellular Energy Story
Mitochondria generate the energy that powers every biological process — and mitochondrial decline is one of the most upstream drivers of aging. NRF2, KLOTHO, SOD2, SIRT1, FOXO3, and MTHFR all converge on mitochondrial biology. The Precision Peptide Genetic Test analyzes 17 Longevity & Aging insights spanning 14 pathways, 49 peptides, and 150+ genetic insights.
The SIRT1 Pathway: Genetics, NAD+, and Cellular Repair
SIRT1 is a NAD+-dependent enzyme that regulates DNA repair, inflammation, metabolic efficiency, and cellular stress response. Variants at rs12778366 and related loci influence how actively SIRT1 operates at baseline. The Precision Peptide Genetic Test analyzes SIRT1 as part of 17 Longevity & Aging insights spanning 14 pathways, 49 peptides, and 150+ genetic insights.
The Complete Guide to Genetic Longevity Testing: 17 Pathway Insights
The Precision Peptide Genetic Test analyzes 17 longevity and aging genetic insights — FOXO3, SOD2, APOE, SIRT1, and TERT among them — within a panel of 14 pathways, 49 peptides, and 150+ genetic insights. This pillar guide breaks down each longevity gene, what it signals about healthspan, and why your DNA is the highest-leverage variable in any aging strategy.
DNA Longevity Testing: What 17 Genetic Insights Reveal
The PlexusDx Precision Peptide Genetic Test analyzes 17 longevity-aging genetic insights across five peptide pathways — Epitalon, FOXO4-DRI, Glutathione, Humanin, and Vilon — covering 15 SNPs across 14 genes including FOXO3, TERT, SIRT1, GPX1, and PPARGC1A. This article explains what each insight reveals and why peptide-specific longevity testing is a distinct category of genetic analysis.