Fridays offers month-to-month and prepaid GLP-1 plans starting at $389/month for tirzepatide. We verified subscription terms, upfront commitments, and cancellation flexibility against PlexusDx's no-lock-in structure through September 2026.

GobyMeds offers dose-tiered prepaid bundles starting at $299 for three months of semaglutide; PlexusDx charges $189/month with no dose tiers or prepayment. Which structure costs less over 12 months depends on your dose and commitment preference.

Cora Health offers four billing options for compounded semaglutide and tirzepatide, with prepaid annual plans delivering the lowest per-month rate but requiring full upfront payment. We break down the 12-month math for each option and show where PlexusDx fits.

10Rx offers only quarterly prepaid GLP-1 packages; PlexusDx provides month-to-month and multi-month options. We compare effective monthly costs, upfront commitments, and flexibility across both models.

Hims & Hers advertises $199/month for compounded semaglutide as part of a 6-month prepaid plan. Several low-cost providers offer month-to-month semaglutide from $189–$299 with no upfront commitment.

Lavender Sky Health advertises prepaid 2-month compounded plans at starting-dose rates, but consultation fees, dose escalation, and monthly brand options add complexity. We calculate effective monthly costs over 12 months for every structure.

Big Easy Weight Loss offers 12-week prepaid cycles starting at advertised promotional rates of $399 semaglutide and $499 tirzepatide, but no monthly billing option or standard refill pricing is documented. PlexusDx runs $189–$289/month with no prepayment required.

Fifty410 offers a $199/month semaglutide plan and prepaid tirzepatide starting at $399 for three months. We calculate the 12-month costs and show which billing model delivers the lowest effective rate.

OrderlyMeds offers a two-month prepaid starter package that lowers your effective monthly cost over the first year—but the ongoing rate jumps after month two.

Zealthy advertises compounded semaglutide at $151/month when billed quarterly, but the full upfront total and membership costs remain undisclosed at the pricing page. We compare transparent monthly options and show the 12-month cost picture.

PlushCare's annual membership saves $70.89 over 12 months compared to monthly billing, but requires $149 upfront. We compare both options with full 12-month cost breakdowns including the initial visit.

Found's monthly cash plan bills 13 times per year; its 12-month prepaid plan locks in a lower effective rate but requires an upfront lump sum. We calculate the true annual cost of each option and show where PlexusDx falls in the spectrum.

Prepaid GLP-1 programs often advertise lower per-month rates, but upfront costs, refund limits, and dose uncertainty change the true math. We normalize monthly, three-month, six-month, and annual commitments across 25 providers to show which structure costs less over twelve months of treatment.

AltRx is running a promotional tirzepatide campaign through September 5, 2026, with rates from $149 per month on a month-to-month basis down to $125 per month prepaid annually. We compare the promotional structure against standard plans and examine what happens when the promotion ends.

BrightMeds tirzepatide costs $149/month on its standard plan or a prepaid rate of $357 per quarter ($119/month equivalent), versus PlexusDx at $289 month-to-month. We compare both billing models, promotional limits, and what the difference means over 12 months.