The Precision Peptide Genetic Test analyzes 6 Reproductive Health insights covering women's hormone pathways — COMT, CYP1A1, CYP1B1, MTHFR, ESR1, and Phase 2 detox genes — within a panel of 14 pathways, 49 peptides, and 150+ genetic insights. This pillar guide breaks down how you produce, clear, and respond to estrogen, and why clearance genetics matter as much as production.

Genetics shapes estrogen in men through four pathways: how much testosterone converts to estradiol (CYP19A1), how efficiently it clears (COMT, MTHFR), how sensitively tissues respond (ESR1), and how much substrate is available (SHBG, SRD5A2). The Precision Peptide Genetic Test maps all these variables across 14 pathways and 150+ genetic insights.

The Precision Peptide Genetic Test analyzes MTHFR C677T and A1298C — the variants that determine your methylation capacity and its downstream effects on estrogen clearance, homocysteine levels, and hormone metabolism. Part of 14 pathways and 150+ genetic insights across 49 peptides, MTHFR is the genetic variable connecting methylation to the male hormone system.

Your Precision Peptide Genetic Test report delivers 150+ insights across 14 pathways, including FOXO3 for longevity, ACTN3 for muscle, and GIPR for weight management. This guide walks through how to read pathway scores, interpret gene variants, and turn findings into the informed conversation every peptide protocol decision should start with.

Genetic peptide testing analyzes how your DNA shapes 14 biological pathways that peptide protocols target — from GLP-1 signaling to growth hormone axis to estrogen clearance. The PlexusDx Precision Peptide Genetic Test delivers 150+ insights across 49 unique peptides, turning peptide decisions from guesswork into evidence-based conversations with your healthcare provider.