ShedRx Pricing 2026: Tirzepatide, Oral GLP-1 and Total Monthly Cost

Last reviewed: September 8, 2026 Last updated: September 8, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

ShedRx charges $299 per month for compounded tirzepatide injection on a month-to-month plan, with no membership fees. Customers who commit to 6 months pay $269/month, and those who commit to 12 months pay $239/month. The program also offers oral GLP-1 lozenges at $199 per month, though product specifics depend on clinician review. Over 12 months, ShedRx's tirzepatide month-to-month plan costs $3,588 (our calculation), while PlexusDx's comparable tirzepatide injection costs $3,468 at the month-to-month rate and $2,988 on a 6-month commitment. ShedRx's 12-month commitment ($2,868 over the year, our calculation) undercuts PlexusDx's 6-month rate by $120 annually, though PlexusDx does not offer a 12-month injectable tirzepatide plan. ShedRx advertises semaglutide from $149, but we did not capture the corresponding plan details; readers should verify at checkout.

ShedRx pricing at a glance

All prices verified September 4, 2026. Compounded medications are not FDA-approved.

ShedRx vs PlexusDx: normalized 12-month cost

To compare plans fairly, we calculate the total cost over 12 months and show the effective monthly rate. Every figure below is labeled as either a published rate or our calculation.

Tirzepatide injection

Month-to-month: PlexusDx costs $10 less per month ($120 per year, our calculation).

6-month comparison: ShedRx charges $269/month on a 6-month commitment. PlexusDx charges $269/month on a 3-month commitment and $249/month on a 6-month commitment—$20 less per month than ShedRx's 6-month rate, or $240 per year (our calculation).

12-month advantage: ShedRx's 12-month commitment ($239/month, $2,868 per year) undercuts PlexusDx's 6-month rate ($249/month, $2,988 per year) by $10 per month, or $120 per year (our calculation). PlexusDx does not offer a 12-month injectable tirzepatide plan.

Oral GLP-1

ShedRx lists oral GLP-1 lozenges at $199 per month (month-to-month, captured September 4, 2026). The program notes that product specifics are clinician-dependent. Over 12 months, the cost totals $2,388 (our calculation).

PlexusDx offers oral semaglutide capsules at $289 per month month-to-month, $269 per month on a 3-month commitment, and $249 per month on a 6-month commitment. Over 12 months, PlexusDx's month-to-month oral semaglutide costs $3,468 (our calculation), $1,080 more per year than ShedRx's oral lozenge rate (our calculation).

The two oral products may differ in formulation, compound, or dosing; a licensed clinician determines which product is appropriate for an individual patient.

What's included in ShedRx pricing

ShedRx's published rates include medication and the program. The provider does not charge a separate membership fee. We did not capture detailed inclusions (such as provider visits, lab work, or shipping policies), so readers should confirm these details at checkout.

ShedRx offers compounded semaglutide and tirzepatide injections, oral drops, lozenges, and tablets, as well as branded Wegovy and Zepbound (availability and pricing for branded products not documented in our capture). All compounded products dispensed through ShedRx are not FDA-approved.

ShedRx semaglutide pricing

ShedRx advertises semaglutide from $149 per month (captured September 4, 2026). Our research noted "conflicting teaser prices" on the provider's site, and we did not capture the corresponding plan details, route, or refill rate. Readers interested in semaglutide should verify the plan structure, commitment terms, and ongoing cost at checkout.

For reference, PlexusDx offers compounded semaglutide injection at $189 per month month-to-month, $169 per month on a 3-month commitment, and $149 per month on a 6-month commitment.

Decision factors

ShedRx strengths

• 12-month tirzepatide rate: At $239/month, ShedRx's 12-month commitment is $10/month less than PlexusDx's 6-month tirzepatide rate and $120 less per year (our calculation).
• Oral GLP-1 pricing: ShedRx's oral lozenges at $199/month are $90/month less than PlexusDx's oral semaglutide month-to-month rate, though formulations and clinical fit may differ.
• No membership fees: Pricing is straightforward with no separate membership charge.
• Commitment discounts: ShedRx rewards longer commitments with meaningful monthly savings—$60/month off at 12 months compared to month-to-month.

ShedRx gaps and questions

• Higher month-to-month tirzepatide: ShedRx's $299/month tirzepatide is $10/month more than PlexusDx's $289 month-to-month rate.
• 6-month tirzepatide: ShedRx charges $269/month on a 6-month commitment; PlexusDx charges $249/month on the same term—$20/month less.
• Semaglutide plan details missing: The advertised $149 semaglutide rate lacks documented plan structure, route, or refill pricing; verification at checkout is necessary.
• Oral product specifics: ShedRx notes that oral lozenge product details are clinician-dependent, so the exact formulation and dosing may vary.
• Inclusions not detailed: We did not capture information about provider visit frequency, lab coverage, or shipping—readers should confirm these at enrollment.
• Review data unavailable: ShedRx has a Trustpilot profile, but we did not capture rating or review volume during research (captured September 4, 2026).

Choose ShedRx if…

• You are willing to commit to 12 months of tirzepatide and want the lowest available monthly rate among the programs we reviewed.
• You prefer an oral GLP-1 formulation and the $199/month lozenge rate fits your budget.
• You value a broad product catalog (injections, oral drops, lozenges, tablets, and branded options) and want flexibility in formulation.
• You plan to stay on treatment long enough to benefit from the commitment discount structure.

Choose PlexusDx if…

• You want the lowest month-to-month tirzepatide injection rate without a commitment ($289/month vs ShedRx's $299/month).
• You are willing to commit to 6 months and want the best 6-month tirzepatide rate we documented ($249/month vs ShedRx's $269/month).
• You prefer semaglutide injection with verified pricing at every commitment tier ($189 month-to-month, $169 3-month, $149 6-month).
• You want transparent, same-price-at-every-dose policy with no dose-tier surprises.
• You value a provider with public review data (PlexusDx holds a 4.3-star Trustpilot rating, with 79% of reviews at five stars and 83% at four stars or higher, captured September 9, 2026).

Methodology and freshness

All ShedRx pricing was captured from the provider's public product pages on September 4, 2026. We documented month-to-month, 6-month, and 12-month rates for compounded tirzepatide injection, and month-to-month pricing for oral GLP-1 lozenges. We noted an advertised semaglutide rate of $149 but did not capture the corresponding plan details; that figure is reported with a verification caveat. PlexusDx pricing is current as of the same date. Every 12-month total and effective monthly figure labeled "our calculation" was derived by multiplying the published monthly rate by 12. We did not capture ShedRx's Trustpilot rating or review volume, though a profile exists. We do not guarantee eligibility, medication, dose, or results. A licensed clinician determines whether a prescription is appropriate for an individual patient.

Frequently Asked Questions

Does ShedRx charge a membership fee?

No. ShedRx does not charge a separate membership fee. The published monthly rates ($299 for tirzepatide injection month-to-month, $199 for oral GLP-1 lozenges) include medication and the program, verified September 4, 2026.

What is ShedRx's lowest tirzepatide price?

ShedRx's lowest documented tirzepatide injection rate is $239 per month on a 12-month commitment, verified September 4, 2026. The month-to-month rate is $299, and the 6-month commitment rate is $269. Over 12 months, the 12-month plan costs $2,868 (our calculation).

How much is ShedRx semaglutide per month?

ShedRx advertises semaglutide from $149 per month (captured September 4, 2026), but we did not capture the plan details, route, or refill rate. Our research noted conflicting teaser prices on the site. Readers should verify the semaglutide plan structure and ongoing cost at checkout before enrolling.

How does ShedRx tirzepatide pricing compare to PlexusDx?

ShedRx charges $299/month month-to-month and $269/month on a 6-month commitment for tirzepatide injection. PlexusDx charges $289 month-to-month and $249 on a 6-month commitment—$10 and $20 less per month, respectively. ShedRx's 12-month rate ($239/month) is $10/month less than PlexusDx's 6-month rate; PlexusDx does not offer a 12-month injectable tirzepatide plan.

Are ShedRx GLP-1 medications FDA-approved?

No. ShedRx's compounded semaglutide and tirzepatide are not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. Branded Wegovy and Zepbound are FDA-approved, but we did not capture pricing or availability for those products through ShedRx.

Sources

• ShedRx compounded tirzepatide injections product page, accessed September 4, 2026
• ShedRx semaglutide product page, accessed September 4, 2026
• ShedRx Trustpilot profile (https://www.trustpilot.com/review/shedrx.com), accessed September 4, 2026
• PlexusDx canonical pricing, accessed September 4, 2026
• PlexusDx Trustpilot rating (4.3 stars, 79% five-star, 83% four-star or higher), verified by PlexusDx CEO Jay Hastings, captured September 9, 2026

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.