Sesame Price: Subscription Tiers and What's Included

Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

This article is part of the PlexusDx Education Hub — evidence-based guidance on GLP-1 therapies, weight management protocols, and the genetic variables that shape every metabolic decision. Browse all Peptides & GLP-1 education

This is an independent editorial review. PlexusDx has no commercial relationship with Sesame or its parent company, and no affiliate links or compensation are involved.

Where a cost breakdown asks what drives the total, a pricing question is about the shape of the offer: how access is priced, what a subscription bundles, and how brand versus compounded splits the figure. This review of Sesame pricing is current as of April 2026.

How Sesame prices access

Sesame (Sesame Care) prices access through its marketplace rather than a single flat membership. A listed provider visit generates the prescription, which routes to a retail pharmacy for FDA-approved brand products or to a 503A compounding pharmacy for compounded semaglutide or tirzepatide. Because the model unbundles visit and medication, the "price" is really a small stack of line items, so the headline number and the checkout total are not always the same figure. Current figures are posted on Sesame's official website.

What a monthly subscription typically bundles

In telehealth GLP-1 programs, a monthly figure may fold in the clinical evaluation, the medication itself, shipping, and follow-up messaging — or it may quote only part of that and add the rest at checkout. Reading the fine print on what is and is not included is the difference between comparing prices fairly and comparing an advertised teaser against a full total. When comparing two programs, the only fair method is to total every recurring line item rather than trust a single advertised rate.

Brand versus compounded and the price gap

The single biggest swing in price is whether you receive an FDA-approved brand product or a compounded alternative. Brand products dispensed through retail pharmacies carry manufacturer list pricing; compounded semaglutide or tirzepatide through a licensed 503A pharmacy is priced differently. Across the telehealth GLP-1 market, monthly totals commonly fall between roughly $200 and $700+ as of April 2026, with wide variance driven largely by this split. Understanding which side of that split a program sits on explains most of the price differences you will encounter across the category.

Reading the total before you subscribe

Before committing to any tier, resolve the full monthly total: which compound, which pharmacy pathway, what is bundled, and what recurs. The pharmacology behind the price is consistent — GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and GIP/GLP-1 dual agonists (tirzepatide), studied in STEP (NEJM 2021), SURMOUNT (NEJM 2022), and SURMOUNT-OSA (NEJM 2024). Verify the current number on the provider's own site first. A quick way to sanity-check any quote is to ask what changes if your dose increases during titration.

How PlexusDx structures its pricing

For a flat, single-figure contrast, PlexusDx prices its Weight Management Protocols transparently: Semaglutide Injection at $189 a month, Tirzepatide Injection at $289 a month, and a microdose option at $129 a month flat. The Precision Peptide Genetic Test is priced at $298, or $99 for program members. Because the figure is flat, it is easy to compare directly against an unbundled marketplace quote.

Pricing genetics into the decision

One input never appears on a subscription tier: your own biology. Variants in FTO, GLP1R, MC4R, and TCF7L2 shape the terrain a GLP-1 compound works on. The Precision Peptide Genetic Test analyzes 14 pathways, 49 peptides, 150+ genetic insights. It never predicts response or sets a dose; it prices upstream context into the decision. Budgeting with that context tends to be steadier than chasing the lowest advertised tier. Not affiliated: PlexusDx has no commercial relationship with Sesame.

Related reading on PlexusDx: GLP 1 Hormone, What Is GLP 1, GLP 1 What Is, GLP 1 Receptor Agonist.

Frequently Asked Questions

How is Sesame pricing structured?

Sesame prices through its marketplace, unbundling a listed provider visit from the medication rather than charging one flat membership. The posted price is effectively a small stack of line items. Because figures change, confirm the current visit and medication pricing directly on the provider's own website before subscribing.

What does a monthly subscription include?

It varies by program. A monthly figure may bundle the clinical evaluation, medication, shipping, and follow-up, or quote only part and add the rest at checkout. Read exactly what is included so you compare full totals rather than an advertised starting price against a complete one.

Why is compounded priced differently than brand?

FDA-approved brand products dispensed through retail pharmacies carry manufacturer list pricing, while compounded semaglutide or tirzepatide from a licensed 503A pharmacy is priced on a different basis. That split is the largest driver of variance, which is why telehealth GLP-1 totals range widely, roughly $200–$700+ per month.

How does PlexusDx pricing compare?

PlexusDx uses flat monthly figures rather than unbundled line items: Semaglutide Injection at $189, Tirzepatide Injection at $289, and a $129 microdose option. The Precision Peptide Genetic Test is $298, or $99 for program members. Compare full monthly totals, and confirm any competitor's current pricing on its own site.

This article is part of the PlexusDx Education Hub. Browse all Peptides & GLP-1 education

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.