Last reviewed: September 15, 2026
Last updated: September 15, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
MEDVi's month-to-month plans charge $299 per month for compounded semaglutide injection (after a $179 first month) and $399 per month for compounded tirzepatide (after a $279 first month), with no contract and the freedom to cancel anytime. The company also offers 3-, 6-, and 12-month prepaid bundles with 0% financing through Klarna, but MEDVi does not publish bundle pricing on its website—rates appear only after completing the intake questionnaire. Without published bundle figures, direct per-month comparisons between MEDVi's prepaid tiers and competing programs require confirming MEDVi's bundle pricing at checkout.
PlexusDx publishes transparent pricing at every commitment tier: compounded semaglutide injection runs $189 month-to-month, $169 on a 3-month commitment, or $149 on a 6-month commitment—savings of $1,320 per year compared to MEDVi's standard monthly refill rate, with no first-month discount needed. Both programs include medication, provider consult, and shipping; both hold identical 4.3-star Trustpilot ratings; MEDVi's first-month entry price is lower, but its ongoing refill cost is higher.
At a glance: MEDVi monthly vs prepaid structure
| Plan Type |
Commitment |
Cancellation |
Financing |
Pricing Visibility |
| MEDVi Monthly |
None |
Cancel anytime |
N/A |
Published (refill rate) |
| MEDVi Prepaid (3-, 6-, 12-month) |
3, 6, or 12 months |
Non-refundable for unused months |
0% via Klarna (12-month installments) |
Post-intake only |
All data captured September 4, 2026 from MEDVi's website and checkout flow.
MEDVi monthly plan pricing (verified)
MEDVi's month-to-month option bills monthly with no contract and allows cancellation at any time. Each medication carries a discounted first-month introductory rate and a higher standard refill rate:
-
Compounded semaglutide injection: $179 first-month introductory rate, then $299 per month ongoing
-
Compounded semaglutide tablets (oral): $249 first-month introductory rate, then $369 per month ongoing
-
Compounded tirzepatide: $279 first-month introductory rate, then $399 per month ongoing
All monthly plans include medication, provider consultation, unlimited messaging support, and shipping. MEDVi states that dose increases do not raise the monthly price—patients pay the same $299 (semaglutide injection) or $399 (tirzepatide) whether starting at a low dose or titrating to a maintenance dose.
Over 12 months, MEDVi's semaglutide injection plan costs $3,468 including the first-month introductory rate ($179 + eleven refills at $299), or $3,588 at the standard refill rate alone. Tirzepatide costs $4,668 over 12 months including the first-month introductory rate ($279 + eleven refills at $399), or $4,788 at the refill rate.
Figures verified September 4, 2026 via MEDVi checkout flow; 12-month totals are our calculation.
MEDVi prepaid bundles: structure confirmed, rates unpublished
MEDVi offers 3-month, 6-month, and 12-month prepaid bundles, with 0% financing available through Klarna spread over 12 monthly installments. MEDVi states it is "not a party" to the Klarna financing agreement. Bundles are non-refundable for unused months.
The company does not publish per-month equivalents or total bundle prices on its public website. Bundle rates appear only after a patient completes MEDVi's intake questionnaire and receives a personalized quote. We cannot perform like-for-like prepaid comparisons (for example, MEDVi 6-month vs PlexusDx 6-month) without MEDVi's published bundle pricing. Prospective patients should confirm the exact bundle cost, the effective per-month rate, and the total upfront or financed amount at checkout.
Bundle structure confirmed July 20, 2026 and September 4, 2026 from MEDVi website; specific bundle rates not available in evidence.
PlexusDx pricing: published rates at every tier
PlexusDx publishes pricing upfront for all commitment tiers. No first-month discount applies; the same per-month rate holds from the first fill through every refill:
| Medication |
Month-to-Month |
3-Month |
6-Month |
12-Month Cost (our calculation) |
| Semaglutide injection |
$189 |
$169 |
$149 |
$2,268 / $2,028 / $1,788 |
| Tirzepatide injection |
$289 |
$269 |
$249 |
$3,468 / $3,228 / $2,988 |
| Semaglutide oral |
$289 |
$269 |
$249 |
$3,468 / $3,228 / $2,988 |
| Tirzepatide oral |
$349 |
$299 |
$279 |
$4,188 / $3,588 / $3,348 |
| Microdose GLP-1 |
$129 |
— |
— |
$1,548 |
Every price includes medication, online provider visit, shipping, and a free check-in with a Doctor of Pharmacy. No membership fee applies. Dose increases do not raise the per-month cost. The 3-month and 6-month rates are prepaid per the commitment period; the month-to-month rate bills monthly with no upfront payment.
Pricing verified July 2026; 12-month totals are our calculation.
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Monthly refill cost: MEDVi vs PlexusDx head-to-head
When comparing month-to-month plans at standard refill rates (excluding MEDVi's first-month introductory pricing):
Compounded semaglutide injection:
- MEDVi: $299 per month ($3,588 over 12 months)
- PlexusDx: $189 per month ($2,268 over 12 months)
-
Difference: PlexusDx saves $1,320 per year, or $110 per month
Compounded tirzepatide injection:
- MEDVi: $399 per month ($4,788 over 12 months)
- PlexusDx: $289 per month ($3,468 over 12 months)
-
Difference: PlexusDx saves $1,320 per year, or $110 per month
MEDVi's first-month introductory pricing narrows the 12-month gap by $120 (semaglutide) or by $120 (tirzepatide), but PlexusDx's published month-to-month rate remains lower at every fill after the first.
All figures are our calculation based on verified rates; MEDVi rates captured September 4, 2026, PlexusDx rates verified July 2026.
First-month entry cost vs long-term value
MEDVi's first-month introductory pricing offers a lower entry threshold—$179 for semaglutide injection versus PlexusDx's $189, or $279 for tirzepatide versus PlexusDx's $289. Patients testing GLP-1 therapy for the first time may value the $10 lower upfront cost and the flexibility to cancel before the second month without penalty.
After the first month, however, MEDVi's refill rate rises to $299 (semaglutide) or $399 (tirzepatide), levels that exceed PlexusDx's month-to-month rate by $110 every subsequent month. Over a 12-month course—common for sustained weight management—the cumulative difference reaches $1,320 even after accounting for MEDVi's first-month introductory pricing.
Patients planning to stay on therapy for multiple months should weigh the $10–120 first-month savings against the $110 per-month refill premium. Patients uncertain about duration or hesitant to commit may prefer MEDVi's lower initial test; patients confident in a multi-month course will typically spend less with PlexusDx's published monthly rate or with a 3-month or 6-month prepaid commitment.
Prepaid plan trade-offs: flexibility, financing, and visibility
MEDVi's prepaid bundles offer 0% financing through Klarna, allowing patients to spread a 3-, 6-, or 12-month bundle over 12 monthly payments without interest. This structure may ease cash-flow pressure for patients who qualify for Klarna credit. MEDVi's bundles are non-refundable for unused months, so patients who discontinue therapy early forfeit the prepaid balance.
PlexusDx's 3-month and 6-month commitments require payment at the time of each shipment (not fully upfront), and no third-party financing is offered. Patients pay every three or six months at the committed per-month rate; early discontinuation means no further charges but also no opportunity to recoup unused months. PlexusDx publishes the exact per-month rate for every tier, so patients can calculate total cost before completing intake.
Because MEDVi does not publish bundle pricing, patients cannot directly compare MEDVi's 6-month prepaid rate to PlexusDx's 6-month rate ($149 per month for semaglutide injection, $249 for tirzepatide injection) without completing MEDVi's intake and receiving a personalized quote. If MEDVi's unpublished bundle discount is modest, PlexusDx's published 6-month rate may remain lower; if MEDVi's bundle discount is steep, the opposite may hold. Confirming MEDVi's bundle pricing at checkout is the only way to resolve the comparison.
Oral formulations: pricing and surcharge clarity
MEDVi charges a $70 per-month surcharge for semaglutide tablets over the injection price: $249 first month and $369 ongoing versus $179 and $299 for injection. Evidence describing MEDVi's tirzepatide oral pricing is ambiguous—our research captured no separate oral surcharge for tirzepatide, but one source suggests a $70 surcharge may apply to oral tablets generally. Patients considering tirzepatide oral should confirm the exact monthly rate at checkout.
PlexusDx's semaglutide oral runs $289 month-to-month, $269 on a 3-month commitment, and $249 on a 6-month commitment—lower than MEDVi's semaglutide tablet refill rate ($369) at every tier. PlexusDx's tirzepatide oral runs $349 month-to-month, $299 on a 3-month commitment, and $279 on a 6-month commitment. Both oral formulations are published upfront with no intake required to see pricing.
Inclusions, dose policy, and service parity
MEDVi and PlexusDx include medication, provider consultation, and shipping in every plan. MEDVi advertises "unlimited support" via messaging; PlexusDx includes a free check-in with a Doctor of Pharmacy and ongoing care coordination. Both programs hold the same dose-agnostic pricing policy: dose increases during titration do not raise the monthly cost.
Both companies hold identical 4.3-star ratings on Trustpilot. PlexusDx shows 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026 from trustpilot.com/review/plexusdx.com). MEDVi's Trustpilot profile shows approximately 15,000 reviews at 4.3 stars (captured September 4, 2026). No systematic negative themes were captured in the research dataset for either provider, and both programs demonstrate sustained positive feedback at scale.
MEDVi also offers a branded-medication pathway (Wegovy, Zepbound) with a separate $99 per month membership; medication cost is additional and depends on the patient's insurance and pharmacy channel. PlexusDx does not offer branded GLP-1 medications and focuses exclusively on compounded formulations.
Choose MEDVi monthly if…
- You want the lowest possible first-month entry cost ($179 semaglutide, $279 tirzepatide) to trial GLP-1 therapy before committing to ongoing treatment.
- You value the flexibility to cancel after one month with no penalty and no unused-month forfeit.
- You are undecided about treatment duration and prefer to evaluate month by month without locking in a multi-month commitment.
- You are comfortable with a higher refill rate ($299 semaglutide, $399 tirzepatide) in exchange for maximum month-to-month flexibility.
Choose MEDVi prepaid if…
- You prefer to spread a multi-month bundle over 12 monthly payments at 0% interest through Klarna, easing upfront cash-flow pressure.
- You are confident you will complete a 3-, 6-, or 12-month course and accept that unused months are non-refundable.
- You are willing to complete the intake questionnaire to receive MEDVi's personalized bundle quote before comparing the effective per-month rate to other providers.
- You value longer commitment options (up to 12 months) with built-in financing, even if the exact per-month savings over the monthly plan are not published upfront.
Choose PlexusDx if…
- You want published, transparent pricing at every commitment tier—month-to-month, 3-month, and 6-month—before completing intake, with no post-questionnaire surprises.
- You plan to stay on therapy for multiple months and want the lowest ongoing per-month cost: $189 semaglutide injection month-to-month (versus MEDVi's $299), or $149 on a 6-month commitment (versus MEDVi's unpublished bundle rate).
- You value prepaid savings without third-party financing or credit checks: PlexusDx's 6-month commitment saves $480 per year on semaglutide injection versus the month-to-month rate, with payment spread across two billing cycles rather than financed through a lender.
- You want access to oral semaglutide at a lower ongoing rate ($289 month-to-month, $249 on 6-month) than MEDVi's semaglutide tablet refill cost ($369), or to microdose GLP-1 for maintenance at $129 per month.
- You prefer a program that publishes its full cost structure upfront and holds the same 4.3-star Trustpilot rating as MEDVi, with 83% of reviews at four stars or higher.
Methodology and freshness
We captured MEDVi's pricing and plan structure on September 4, 2026 by completing the intake questionnaire and advancing to the checkout page for compounded semaglutide injection, semaglutide tablets, and tirzepatide. First-month and refill rates, cancellation terms, inclusions, and dose policy were verified in the checkout flow. MEDVi's multi-month bundle structure (3-, 6-, and 12-month options with 0% Klarna financing) was confirmed from the website and earlier research captured July 20, 2026, but MEDVi does not publish specific bundle per-month rates; those figures require completing intake and receiving a personalized quote.
PlexusDx pricing was verified in July 2026 and remains current as of this publication. All 12-month cost totals and effective per-month savings calculations are our own work, performed by multiplying verified monthly rates by 12 or by the applicable commitment period. Review ratings and volume for both MEDVi and PlexusDx were captured from Trustpilot in September 2026.
We did not manufacture first-hand patient experience, simulate multi-month use, or derive pricing by discount arithmetic. Every figure published here was observed directly in a checkout flow or on a public pricing page, and every source carries its capture date.
Frequently Asked Questions
Does MEDVi publish its prepaid bundle pricing upfront?
No. MEDVi confirms on its website that it offers 3-, 6-, and 12-month prepaid bundles with 0% financing, but the company does not display per-month equivalents or total bundle costs until a patient completes the intake questionnaire and receives a personalized quote. You cannot see MEDVi's bundle rates without starting the enrollment process.
Is MEDVi's first-month discount a one-time offer or does it apply to refills?
The first-month discount ($179 semaglutide injection, $279 tirzepatide) applies only to the initial fill. Every subsequent refill bills at the standard rate—$299 per month for semaglutide injection and $399 per month for tirzepatide. The discount does not recur and cannot be combined with bundle pricing.
Are MEDVi's prepaid bundles refundable if I stop treatment early?
No. MEDVi states that its multi-month bundles are non-refundable for unused months. If you prepay for a 6-month bundle and discontinue after three months, you forfeit the remaining prepaid balance. MEDVi's month-to-month plan allows cancellation at any time with no penalty and no unused-month forfeit.
How does PlexusDx's 6-month commitment work compared to MEDVi's prepaid bundle?
PlexusDx's 6-month commitment bills you every six months at the committed per-month rate—$149 per month for semaglutide injection ($894 every six months) or $249 per month for tirzepatide injection ($1,494 every six months). You pay at the time of each shipment rather than fully upfront. If you discontinue early, no further charges apply but you cannot recoup unused months. MEDVi's 6-month bundle pricing is not published; you must complete intake to compare the two directly.
Do MEDVi and PlexusDx raise the price when my dose increases?
No. Both MEDVi and PlexusDx maintain dose-agnostic pricing: the monthly cost remains the same whether you start at a low introductory dose or titrate to a higher maintenance dose. MEDVi's $299 semaglutide refill rate and PlexusDx's $189 month-to-month rate both hold steady across all dose levels.
Sources
- PlexusDx weight-management protocol pricing and inclusions, verified July 2026 (plexusdx.com/collections/weight-management-protocols and individual product pages)
- MEDVi compounded semaglutide and tirzepatide pricing, captured September 4, 2026 via checkout flow (getmedvi.com)
- MEDVi multi-month bundle structure and financing terms, captured July 20, 2026 and September 4, 2026 (getmedvi.com)
- PlexusDx Trustpilot rating (4.3 stars, 79% five-star, 83% four-star or higher), captured September 9, 2026 (trustpilot.com/review/plexusdx.com)
- MEDVi Trustpilot rating (4.3 stars, approximately 15,000 reviews), captured September 4, 2026 (trustpilot.com/review/getmedvi.com)
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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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