Last reviewed: September 11, 2026 Last updated: September 11, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

IVIM Health sells compounded semaglutide in prepaid 4-month ($499) or 6-month ($600) medication bundles, plus a separate $75/month membership fee (first month free). Over 12 months, the 6-month bundle path costs $2,025 total—$168.75/month effective—while the 4-month path costs $2,322 total—$193.50/month effective (our calculation). PlexusDx month-to-month compounded semaglutide injection is $189/month with no membership and no prepayment, totaling $2,268 over 12 months. IVIM's 6-month bundle delivers the lowest 12-month cost if you prepay $600 twice and stay the full year; PlexusDx costs $243 more over 12 months but carries no upfront commitment and no recurring membership charge.

Comparing prepaid bundles against month-to-month?

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At a glance: IVIM Health vs PlexusDx semaglutide

IVIM Health
(6-month bundle)
IVIM Health
(4-month bundle)
PlexusDx
Medication bundle $600 prepaid (6 months) $499 prepaid (4 months) $189/month MTM
Membership $75/month (month 1 free) $75/month (month 1 free) $0
First-month cash $600 $499 $189
12-month total $2,025 $2,322 $2,268
Effective monthly $168.75 $193.50 $189
Medication Compounded semaglutide injection Compounded semaglutide injection
Commitment 6 months prepaid 4 months prepaid None

IVIM Health pricing captured September 4, 2026 (ivimhealth.com). PlexusDx pricing verified September 11, 2026. Effective monthly rates over 12 months are our calculation.

IVIM Health pricing structure: medication bundles and membership

IVIM Health separates medication and membership into two charges. The medication—compounded semaglutide or tirzepatide—is sold only in prepaid multi-month bundles (4-month or 6-month). Membership is billed separately at $75/month; the first membership month is free. No month-to-month medication option was documented in the September 4, 2026 capture.

Compounded semaglutide bundles

  • 6-month bundle: $600 upfront—$100/month equivalent over the prepaid period.
  • 4-month bundle: $499 upfront—$124.75/month equivalent over the prepaid period.

Compounded tirzepatide bundles

  • 6-month bundle: $1,100 upfront—$183.33/month equivalent over the prepaid period.
  • 4-month bundle: $900 upfront—$225/month equivalent over the prepaid period.

Every bundle figure above is a prepaid per-month equivalent; you pay the full bundle cost at the start of each cycle. The membership fee is separate and recurs monthly.

What you pay in the first month

Your first-month outlay at IVIM Health depends on which bundle you choose:

  • Semaglutide 6-month: $600 medication + $0 membership (first month free) = $600 cash upfront.
  • Semaglutide 4-month: $499 medication + $0 membership = $499 cash upfront.
  • Tirzepatide 6-month: $1,100 medication + $0 membership = $1,100 cash upfront.
  • Tirzepatide 4-month: $900 medication + $0 membership = $900 cash upfront.

Starting in month two, you pay $75/month membership until your next bundle runs out; then you prepay the next bundle and membership continues monthly.

12-month cost breakdown: IVIM Health semaglutide

To compare IVIM's prepaid model against month-to-month pricing, we calculated the total outlay over 12 months for both bundle paths, assuming you renew at the same bundle size.

6-month bundle path (renewed once at month 7)

  • Medication: $600 × 2 bundles = $1,200.
  • Membership: Month 1 free, then $75 × 11 months = $825.
  • 12-month total: $1,200 + $825 = $2,025.
  • Effective monthly rate: $2,025 ÷ 12 = $168.75/month (our calculation).

4-month bundle path (three cycles over 12 months)

  • Medication: $499 × 3 bundles = $1,497.
  • Membership: Month 1 free, then $75 × 11 months = $825.
  • 12-month total: $1,497 + $825 = $2,322.
  • Effective monthly rate: $2,322 ÷ 12 = $193.50/month (our calculation).

The 6-month bundle delivers a lower 12-month cost—$297 less than the 4-month path—but requires $600 upfront twice instead of $499 three times.

12-month cost breakdown: IVIM Health tirzepatide

6-month bundle path (renewed once at month 7)

  • Medication: $1,100 × 2 bundles = $2,200.
  • Membership: Month 1 free, then $75 × 11 months = $825.
  • 12-month total: $2,200 + $825 = $3,025.
  • Effective monthly rate: $3,025 ÷ 12 = $252.08/month (our calculation).

4-month bundle path (three cycles over 12 months)

  • Medication: $900 × 3 bundles = $2,700.
  • Membership: Month 1 free, then $75 × 11 months = $825.
  • 12-month total: $2,700 + $825 = $3,525.
  • Effective monthly rate: $3,525 ÷ 12 = $293.75/month (our calculation).

Again, the 6-month bundle path saves $500 over 12 months compared to three 4-month cycles, at the cost of larger upfront payments.

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PlexusDx pricing: month-to-month, no membership

PlexusDx sells compounded semaglutide and tirzepatide injections at a fixed monthly rate with no membership fee, no upfront bundle, and no prepayment:

  • Semaglutide injection: $189/month month-to-month.
  • Tirzepatide injection: $289/month month-to-month.

The price is the same at every dose. Over 12 months:

  • Semaglutide: $189 × 12 = $2,268 total.
  • Tirzepatide: $289 × 12 = $3,468 total.

Each monthly charge includes the provider visit, prescription, compounded medication, and shipping. No additional fees.

Head-to-head: semaglutide 12-month cost

Provider & Plan Medication Cost Membership Cost 12-Month Total Effective Monthly
IVIM 6-month bundle $1,200 $825 $2,025 $168.75
PlexusDx MTM $2,268 $0 $2,268 $189
IVIM 4-month bundle $1,497 $825 $2,322 $193.50

All effective monthly rates are our calculation. IVIM membership cost reflects month 1 free, then $75 × 11.

IVIM's 6-month bundle path costs $243 less over 12 months than PlexusDx. The 4-month bundle path costs $54 more than PlexusDx over the same period. PlexusDx sits between the two IVIM options on annual cost but requires no upfront commitment beyond the first $189.

Head-to-head: tirzepatide 12-month cost

Provider & Plan Medication Cost Membership Cost 12-Month Total Effective Monthly
IVIM 6-month bundle $2,200 $825 $3,025 $252.08
PlexusDx MTM $3,468 $0 $3,468 $289
IVIM 4-month bundle $2,700 $825 $3,525 $293.75

All effective monthly rates are our calculation.

For tirzepatide, IVIM's 6-month bundle path costs $443 less over 12 months than PlexusDx. The 4-month path costs $57 more. PlexusDx again sits in the middle on annual cost, with no prepayment required.

Key decision factors

Upfront commitment

IVIM Health requires $499–$1,100 upfront depending on medication and bundle length. You prepay 4 or 6 months of medication at once, then renew the same way when the bundle runs out. PlexusDx bills $189 or $289 once per month with no bundle or prepayment.

Membership vs all-in pricing

IVIM charges $75/month membership separately from medication (first month free). PlexusDx includes the provider visit, prescription, medication, and shipping in one monthly price with no membership layer.

12-month cost advantage

If you stay the full 12 months and choose IVIM's 6-month bundle for either medication, you save $243 (semaglutide) or $443 (tirzepatide) compared to PlexusDx. If you choose IVIM's 4-month bundle, you pay slightly more than PlexusDx over 12 months.

Flexibility to pause or stop

PlexusDx month-to-month billing lets you pause or stop at the end of any month with no prepaid medication left unused. IVIM's prepaid bundles mean medication paid upfront is committed; if you stop early, that portion is already spent.

State and dose eligibility

IVIM notes that state and dose eligibility varies. Confirm availability in your state and at your target dose before committing to a bundle.

Choose IVIM Health if…

  • You are confident you will stay on treatment for at least 12 months and can prepay $600 or $1,100 twice during that period.
  • You want the lowest 12-month total cost and are comfortable with a recurring $75/month membership on top of medication bundles.
  • You prefer to lock in 4 or 6 months of medication at once rather than manage monthly billing.
  • Your state and dose are confirmed eligible under IVIM's service area and formulary.

Choose PlexusDx if…

  • You want month-to-month flexibility with no upfront bundle or prepayment beyond the first month.
  • You prefer a single all-inclusive monthly price—provider visit, prescription, medication, and shipping—with no separate membership fee.
  • You value the ability to pause or stop at the end of any month without prepaid medication left unused.
  • You want the same price at every dose, from start dose through maintenance, with no tiering or add-ons.

PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com).

Methodology and freshness

IVIM Health pricing, membership terms, and bundle structure verified September 4, 2026 from ivimhealth.com. PlexusDx pricing verified September 11, 2026 from plexusdx.com. All 12-month totals, effective monthly rates, and per-month equivalents of prepaid bundles are our calculation. We assumed IVIM's 6-month bundle renews once at month 7 and the 4-month bundle renews at months 5 and 9; we assumed the first membership month is free and months 2–12 are billed at $75 each. State and dose eligibility, branded medication pricing, and detailed clinical protocols were not captured and are not covered. No guarantee is made regarding eligibility, medication availability, dose, or continuation of any promotional offer. Confirm all pricing, bundle terms, and membership fees at checkout before committing to any prepaid plan.

Frequently Asked Questions

Does IVIM Health offer month-to-month semaglutide without a bundle?

No month-to-month medication option was documented in the September 4, 2026 capture. IVIM sells compounded semaglutide only in prepaid 4-month ($499) or 6-month ($600) bundles, with a separate $75/month membership (first month free).

What is the total first-month cost at IVIM Health for semaglutide?

If you choose the 6-month bundle, you pay $600 upfront for medication plus $0 membership (first month free), totaling $600. The 4-month bundle is $499 upfront plus $0 membership, totaling $499. Starting in month two, you pay $75/month membership until your next bundle is due.

Which IVIM bundle has the lowest 12-month cost?

The 6-month bundle renewed once delivers a 12-month total of $2,025 for semaglutide or $3,025 for tirzepatide (our calculation). The 4-month bundle path costs $2,322 (semaglutide) or $3,525 (tirzepatide) over the same period, because you prepay smaller amounts more frequently.

How does IVIM Health semaglutide compare to PlexusDx over 12 months?

IVIM's 6-month bundle path costs $2,025 total, saving $243 versus PlexusDx ($2,268) if you stay the full year. IVIM's 4-month path costs $2,322, which is $54 more than PlexusDx. PlexusDx requires no upfront bundle or membership and bills $189/month with no prepayment.

Can I pause or stop IVIM Health without losing prepaid medication?

Because IVIM bundles are prepaid for 4 or 6 months at a time, stopping early means the unused portion of that bundle is already paid. PlexusDx month-to-month billing lets you pause or stop at the end of any month with no prepaid medication left unused.

Sources

  • PlexusDx semaglutide and tirzepatide injection pricing, verified September 11, 2026, plexusdx.com/products/semaglutide-injection and plexusdx.com/products/tirzepatide-injection.
  • IVIM Health pricing, bundles, and membership terms, captured September 4, 2026, ivimhealth.com.
  • PlexusDx Trustpilot rating (4.3 stars, 79% five-star, 83% four stars or higher), captured September 9, 2026, trustpilot.com/review/plexusdx.com.

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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