Last reviewed: September 24, 2026
Last updated: September 24, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
Fridays Health holds a 4.2-star rating on Trustpilot with approximately 4,700 reviews (captured September 4, 2026; trustpilot.com/review/joinfridays.com), indicating broad user engagement and generally positive sentiment. The program bundles unlimited provider visits, one-on-one dietitian support, nutrition and mental-health coaching, and advertises $0 membership, signup, and lab fees. Compounded tirzepatide pricing ranges from $389 per month month-to-month (captured September 4, 2026 at product page; joinfridays.com/tirzepatide) to an effective $224 per month under the four-for-three promotional plan (which requires an $896 upfront commitment for four months' supply, checked September 4, 2026). Compounded semaglutide is advertised at $249 per month month-to-month (captured July 20, 2026; joinfridays.com/pricing), though an advertised lowest figure of $117 per month appears on promotional landing pages (checked September 4, 2026) without clear eligibility terms. Pricing inconsistencies across Fridays' web properties—campaign landing pages priced differently from joinfridays.com/pricing when captured July 20, 2026, and promotional pages showing rates that differ from product-page standard prices—complicate direct comparison and warrant confirming final cost at checkout. PlexusDx offers compounded tirzepatide injection at $289 per month month-to-month with no membership fee, $269 per month on a three-month commitment, and $249 per month on a six-month commitment (captured July 20, 2026; plexusdx.com), and holds a 4.3-star Trustpilot rating with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). Fridays' advantage lies in its comprehensive support infrastructure—unlimited visits and dedicated dietitian access at no extra charge—while PlexusDx offers simpler, lower base pricing with transparent, published rates and a PharmD check-in included at no cost.
Need GLP-1 medication with straightforward pricing and pharmacist support?
Compare tirzepatide and semaglutide options with transparent monthly rates and no hidden fees.
See PlexusDx Weight Management Protocols →
At-a-glance comparison
| Feature |
Fridays Health |
PlexusDx |
| Trustpilot rating |
4.2 stars, ~4,700 reviews (checked 2026-09-04)
|
4.3 stars, 79% five-star (checked 2026-09-09)
|
| Tirzepatide MTM |
$389/mo product page $359/mo pricing page (discrepancy noted; confirm at checkout)
|
$289/mo |
| Semaglutide MTM |
$249/mo standard $117/mo advertised lowest (promo; terms unclear)
|
$189/mo |
| Membership fee |
$0 |
$0 |
| Included support |
Unlimited provider visits, 1-on-1 dietitian, nutrition & mental-health coaching, care coach |
Free PharmD check-in; optional genetics add-on ($99 program members, $298 standalone) |
| Lab fees |
$0 advertised |
Included in medication price |
| Shipping |
Free (captured at checkout) |
Free |
| Medication type |
Compounded injections; branded options available |
Compounded injections, oral capsules, microdose |
All prices checked July–September 2026. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient.
Trustpilot and Reddit user sentiment
Fridays Health's 4.2-star Trustpilot rating across approximately 4,700 reviews (checked September 4, 2026; trustpilot.com/review/joinfridays.com) reflects a large, actively engaged user base and generally positive experience. The volume places Fridays among the most-reviewed telehealth GLP-1 providers on the platform. No dominant negative theme or attributable complaint excerpt was captured in indexed Trustpilot or Reddit results during the September 2026 research pass, suggesting that while individual service issues and medication experience concerns likely appear—as they do for all telehealth providers—no single systemic problem has risen to the level of recurring public narrative. This pattern differs from providers whose Trustpilot profiles show concentrated threads around billing disputes, delayed shipments, or prior-authorization challenges.
PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). The two providers' review profiles are within one-tenth of a star, indicating comparable overall user satisfaction at the aggregate level.
Normalized pricing: like-for-like twelve-month cost
Fridays Health's advertised tirzepatide pricing shows internal inconsistency: the main pricing page listed $359 per month when captured July 20, 2026 (joinfridays.com/pricing), while the product page listed $389 per month for the one-month plan when checked September 4, 2026 (joinfridays.com/tirzepatide). We use the more recent product-page figure ($389 per month) as the standard month-to-month rate for twelve-month calculations below, but the $30 discrepancy underscores the need to confirm pricing at checkout. Promotional landing pages advertise a lowest semaglutide rate of $117 per month and tirzepatide at $190 per month (checked September 4, 2026), but eligibility terms, duration, and refill rates are not specified on those pages; these figures appear well below standard rates and should be treated as conditional introductory offers until confirmed.
Fridays Health tirzepatide – twelve-month cost
-
Month-to-month ($389/mo standard): 12 × $389 = $4,668 per year (our calculation). No prepayment, no lock-in.
-
Three-month prepaid plan: $896 upfront every three months (effective $298.67/mo; checked September 4, 2026). Four cycles per year: 4 × $896 = $3,584 per year (our calculation). Requires subscription commitment.
-
Four-for-three promotional plan: $896 upfront covers four months (effective $224/mo over those four months; checked September 4, 2026). Three cycles per year: 3 × $896 = $2,688 per year (our calculation), or $224/mo effective rate (our calculation). Requires committing to three months and cycling the promotion three times in twelve months.
-
Six-month prepaid plan: $1,650 upfront every six months (effective $275/mo; checked September 4, 2026). Two cycles per year: 2 × $1,650 = $3,300 per year (our calculation).
-
Twelve-month prepaid plan: $2,880 upfront (effective $240/mo; checked September 4, 2026). One payment per year: $2,880 per year.
The four-for-three promotion delivers Fridays' lowest effective monthly rate at $224 over twelve months, but it requires the largest number of renewal decisions (three separate $896 payments) and assumes the promotional structure remains available throughout the year.
PlexusDx tirzepatide – twelve-month cost
-
Month-to-month ($289/mo): 12 × $289 = $3,468 per year (our calculation). No prepayment, cancel anytime.
-
Three-month commitment ($269/mo): 12 × $269 = $3,228 per year (our calculation). No upfront lump sum; billed monthly at the commitment rate.
-
Six-month commitment ($249/mo): 12 × $249 = $2,988 per year (our calculation). No upfront lump sum; billed monthly at the commitment rate.
PlexusDx's six-month commitment rate ($249/mo, $2,988/year) is $300 per year more expensive than Fridays' four-for-three promotional effective rate ($224/mo, $2,688/year), but it is a published standing rate that does not require cycling a limited-time offer. PlexusDx's month-to-month rate ($289/mo, $3,468/year) is $1,200 per year less than Fridays' standard month-to-month rate ($389/mo, $4,668/year) and requires no commitment.
See your tirzepatide eligibility and transparent monthly rate
A licensed provider reviews your intake and determines whether a prescription is appropriate—$0 charged until approval.
Start My 60-Second Intake →About 60 seconds · $0 charged until provider approval.
What Fridays includes that PlexusDx does not
Fridays Health's headline advantage is its support infrastructure. The program includes unlimited provider visits, one-on-one dietitian consultations, nutrition coaching, mental-health coaching, and a dedicated care coach—all at no separate charge beyond the medication price (captured July 20, 2026; joinfridays.com). Required labs typically include comprehensive metabolic panel, hemoglobin A1C, TSH, and lipid panel, also at $0 advertised lab fee (captured July 20, 2026). For patients who value frequent clinical check-ins, structured nutrition guidance, or integrated behavioral support during weight management, this bundled model addresses multiple dimensions of care within a single monthly payment.
PlexusDx includes a free PharmD check-in with every prescription but does not bundle dietitian visits, mental-health coaching, or unlimited provider consultations. The program offers an optional genetic testing add-on ($99 for program members, $298 standalone; captured July 20, 2026) to guide medication and dose selection, but ongoing behavioral and nutrition support are not part of the core offering. Patients who prefer to manage diet, exercise, and mental health independently—or who already have those resources through insurance or other channels—may not require the Fridays bundle and can capture savings through PlexusDx's lower base medication price.
What PlexusDx offers that Fridays does not
PlexusDx provides five medication formats: compounded semaglutide and tirzepatide injections, semaglutide and tirzepatide oral capsules, and a microdose GLP-1 injection protocol (captured July 20, 2026; plexusdx.com). The microdose option is priced at $129 per month month-to-month and is designed for patients seeking maintenance-level support or stepping down from higher doses. Fridays offers compounded semaglutide and tirzepatide injections and advertises that branded options are available (checked September 4, 2026), but oral and microdose compounded formats were not listed at the time of capture.
PlexusDx publishes a single set of rates across its website with differentiation only by medication, format, and commitment term (month-to-month, three-month, six-month). Pricing is consistent between the main site, product pages, and collections. Fridays' pricing varies across web properties: the main pricing page, product pages, and promotional landing pages showed different figures when captured between July and September 2026, and the $30 tirzepatide month-to-month discrepancy between pricing page ($359) and product page ($389) was still present at the September 4 check. This variance does not necessarily indicate a service-quality issue—promotional campaigns and A/B testing are standard e-commerce practices—but it does require the prospective patient to verify final cost at checkout rather than relying on a single advertised figure.
Pricing transparency and stability
The evidence shows three categories of Fridays pricing, each captured from different parts of the joinfridays.com domain:
-
Standard product-page rates (checked September 4, 2026): Tirzepatide month-to-month $389, three-month prepaid $896 ($298.67/mo equivalent), six-month prepaid $1,650 ($275/mo equivalent), twelve-month prepaid $2,880 ($240/mo equivalent), and four-for-three promotion $896 for four months ($224/mo effective over four months).
-
Advertised pricing-page rates (captured July 20, 2026): Tirzepatide $359 per month, semaglutide $249 per month.
-
Promotional landing-page "advertised lowest" rates (checked September 4, 2026): Semaglutide $117 per month, tirzepatide $190 per month, with no clear eligibility or duration terms visible on those pages.
Campaign landing pages priced differently from joinfridays.com/pricing when captured on July 20, 2026, and promotional landing-page prices continued to differ from product-page standard prices at the September 4, 2026 check. The $117 semaglutide and $190 tirzepatide figures are 53–63% below the standard month-to-month rates, suggesting they are conditional introductory offers, first-month rates, or multi-month prepaid equivalents—but without accompanying terms on the landing page, their basis cannot be confirmed from public evidence. Prospective patients should request a line-item breakdown at intake or checkout that separates any introductory period from the refill rate and confirms upfront-payment requirements.
PlexusDx pricing was uniform across all captured pages (main site, collections, product pages) on July 20, 2026, and the published rates have remained stable since the program's commercial launch.
Choose Fridays Health if…
- You want unlimited access to a provider, one-on-one dietitian visits, and integrated nutrition and mental-health coaching within your monthly medication cost, and you value having one team coordinate all aspects of your weight-management program.
- You are comfortable confirming final pricing at checkout and navigating discrepancies between the pricing page, product page, and promotional landing pages to identify the rate and prepayment structure that apply to your situation.
- You prefer a program with a large Trustpilot user base (approximately 4,700 reviews) and are reassured by a 4.2-star aggregate rating that suggests broad user satisfaction without a dominant public complaint theme.
- You can commit to a multi-month prepaid plan (particularly the four-for-three or twelve-month option) to capture per-month rates below $250, and you are prepared to make the associated upfront payment ($896 or $2,880) and manage renewal timing.
Where PlexusDx fits
- You want a lower base medication price with simpler, published pricing—month-to-month tirzepatide at $289 (vs. Fridays' $389 standard product-page rate) or $249 on a six-month commitment (vs. Fridays' $275 six-month prepaid equivalent or $224 four-for-three effective rate).
- You prefer not to bundle dietitian, mental-health coaching, and unlimited provider visits into your medication cost, either because you already have those resources or because you want the flexibility to add support services separately as needed.
- You value rate transparency and stability: one set of prices across the website, no promotional-landing-page figures that differ from product-page rates, and monthly billing at the commitment rate rather than large upfront lump sums.
- You are interested in format options beyond standard injections—oral semaglutide or tirzepatide capsules (for patients who prefer to avoid injections) or the $129/month microdose protocol (for maintenance or step-down phases).
- You want a provider with a comparable Trustpilot rating (4.3 stars, 79% five-star, 83% four-star or higher) and a track record of transparent patient communication, evidenced by the public review profile and the absence of hidden-fee complaints in captured reviews.
Methodology and freshness
This comparison draws on commercial and review evidence captured between July 20 and September 9, 2026. Fridays Health pricing was recorded from joinfridays.com/pricing (July 20, 2026), product pages including joinfridays.com/tirzepatide (September 4, 2026), and promotional landing pages (September 4, 2026). The tirzepatide month-to-month rate conflict ($359 on the pricing page vs. $389 on the product page) is documented with both dates; we use the more recent product-page figure for twelve-month calculations and note the discrepancy. Advertised-lowest figures ($117 semaglutide, $190 tirzepatide) are treated as promotional and labeled accordingly because they lack visible eligibility or refill-rate context on the landing pages where they appear. PlexusDx pricing and inclusions were captured July 20, 2026 from plexusdx.com and its product pages. Trustpilot ratings for Fridays (4.2 stars, ~4,700 reviews) were checked September 4, 2026 at trustpilot.com/review/joinfridays.com; PlexusDx (4.3 stars, 79% five-star) were checked September 9, 2026 at trustpilot.com/review/plexusdx.com. Reddit was searched for Fridays-specific threads; no negative excerpt or attributable complaint theme was coded in the September 2026 pass. Twelve-month cost figures are our calculations, derived by multiplying stated monthly or prepaid rates by the number of cycles required to cover twelve months. All compounded-medication facts apply to 503A compounding pharmacies. Readers should confirm current pricing, plan terms, prepayment requirements, and medication availability at intake or checkout, as promotional offers and standard rates may change.
Frequently Asked Questions
Why does Fridays Health show different prices on different pages?
Fridays' main pricing page listed tirzepatide at $359/month when captured in July 2026, while the product page showed $389/month in September 2026, and promotional landing pages advertised $117 semaglutide and $190 tirzepatide without clear terms. Promotional campaigns and A/B testing can produce page-level variation; confirm the final rate and any introductory-period limits at checkout.
Is Fridays' 4.2-star Trustpilot rating considered good?
Yes. A 4.2-star average across approximately 4,700 reviews indicates broad user engagement and generally positive experience. PlexusDx holds a 4.3-star rating with 79% five-star reviews; the two providers are within one-tenth of a star at the aggregate level, reflecting comparable overall satisfaction.
Does PlexusDx include dietitian visits like Fridays does?
No. PlexusDx includes a free PharmD check-in with every prescription but does not bundle dietitian consultations, mental-health coaching, or unlimited provider visits. Fridays includes all of those at no separate charge. Patients who want integrated behavioral and nutrition support may prefer Fridays; those who manage diet and exercise independently can save money with PlexusDx's lower base medication price.
Which program has the lowest twelve-month tirzepatide cost?
Fridays' four-for-three promotional plan yields $2,688 per year ($224/month effective rate) if you cycle the $896 four-month payment three times, but it requires three separate upfront commitments and assumes the promotion remains available. PlexusDx's six-month commitment rate is $2,988 per year ($249/month), $300 more annually but published and stable with no promotional cycling required.
Are the medications from Fridays and PlexusDx FDA-approved?
No. Both providers dispense compounded semaglutide and tirzepatide, which are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. Fridays advertises that branded FDA-approved options are available; PlexusDx offers compounded formulations only.
Sources
- Fridays Health pricing and inclusions, joinfridays.com/pricing and product pages (accessed July 20, 2026 and September 4, 2026)
- Fridays Health Trustpilot profile, trustpilot.com/review/joinfridays.com (checked September 4, 2026)
- PlexusDx pricing, product pages, and inclusions, plexusdx.com (accessed July 20, 2026)
- PlexusDx Trustpilot profile, trustpilot.com/review/plexusdx.com (checked September 9, 2026)
- Reddit search for Fridays Health user reports (performed September 2026)
Ready to see your GLP-1 eligibility and transparent monthly rate?
One all-inclusive price covers your online provider visit, prescription, medication, and shipping—no membership, no hidden fees. Complete a short intake and a licensed provider reviews your fit.
Start My Intake →
Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
Share:
Cora Health Membership Fees Explained: What Medication Costs Extra?
Hims & Hers vs Found: Which GLP-1 Program Delivers Better Value