Last reviewed: September 7, 2026 Last updated: September 7, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Fridays Health charges $389 per month for compounded tirzepatide on a month-to-month plan, with no membership fee, no signup charge, and no lab fees (product-page rate captured September 4, 2026). The all-inclusive price covers medication, unlimited provider visits, dietitian support, nutrition and mental-health coaching, a care coach, and free shipping. Prepaid multi-month subscriptions reduce the effective monthly cost: a 3-month plan costs $298.67 per month (our calculation, $896 upfront), a 4-for-3 promotional structure costs $224 per month (our calculation, $896 upfront for four months of medication), a 6-month plan costs $275 per month (our calculation, $1,650 upfront), and a 12-month plan costs $240 per month (our calculation, $2,880 upfront). A pricing conflict exists in the captured evidence: Fridays' pricing summary page advertised $359 per month for tirzepatide as of July 20, 2026, while the product checkout page shows $389 as of September 4, 2026—readers should confirm the current rate at checkout. For reference, PlexusDx offers compounded tirzepatide injection at $289 per month with no lock-in, $269 per month on a 3-month standing rate, and $249 per month on a 6-month standing rate, all with no membership fee.

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Fridays Health vs PlexusDx: At-a-glance comparison

Item Fridays Health PlexusDx
Tirzepatide month-to-month $389/month $289/month
Tirzepatide 3-month $298.67/month (prepaid, our calculation; $896 upfront) $269/month (billed monthly)
Tirzepatide 6-month $275/month (prepaid, our calculation; $1,650 upfront) $249/month (billed monthly)
Tirzepatide 12-month $240/month (prepaid, our calculation; $2,880 upfront) No 12-month tier
4-for-3 promotional plan $224/month (prepaid, our calculation; $896 upfront for 4 months) Not offered
Membership fee $0 $0
Signup fee $0 $0
Lab fees $0 $0
Shipping Free Free
Bundled support Unlimited provider visits, 1-on-1 dietitian, nutrition and mental-health coaching, care coach Free PharmD check-in; optional genetics add-on ($99 for members)
Compounded medication disclosure Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient.

Fridays pricing captured from product pages September 4, 2026; PlexusDx pricing captured September 7, 2026. Prepaid monthly equivalents are our calculation.

Breaking down Fridays Health's pricing structure

Fridays Health offers compounded tirzepatide through five subscription tiers, all with unlimited provider visits, dietitian support, coaching, and free shipping included. The medication itself is compounded—not FDA-approved—and prescribed by a licensed clinician after eligibility review.

Month-to-month plan: $389 per month

The flexible month-to-month option charges $389 per month, billed monthly, with no lock-in (product-page rate captured September 4, 2026). Over 12 months, this totals $4,668 (our calculation). A pricing conflict exists in the evidence: Fridays' pricing summary page advertised $359 per month for tirzepatide as of July 20, 2026, while the product checkout page shows $389 as of September 4, 2026. The company profile notes that "promo landing-page prices differ from product-page standard prices." We use the more recent product-page figure; confirm the current rate at checkout.

3-month prepaid plan: $298.67 per month equivalent

The 3-month subscription requires $896 upfront for three months of medication, yielding an effective rate of $298.67 per month (our calculation). Over 12 months, four cycles total $3,584 (our calculation), saving $1,084 compared to the month-to-month plan if you remain enrolled for a full year.

4-for-3 promotional plan: $224 per month equivalent

The 4-for-3 structure charges $896 upfront and delivers four months of medication—commit to three months and receive the fourth free. The effective rate is $224 per month (our calculation). Over 12 months, three cycles total $2,688 (our calculation), saving $1,980 compared to month-to-month. This promotional plan offers the lowest effective monthly cost captured in the evidence.

6-month prepaid plan: $275 per month equivalent

The 6-month subscription requires $1,650 upfront, yielding an effective rate of $275 per month (our calculation). Over 12 months, two cycles total $3,300 (our calculation), saving $1,368 compared to month-to-month.

12-month prepaid plan: $240 per month equivalent

The 12-month subscription requires $2,880 upfront, yielding an effective rate of $240 per month (our calculation). This annual commitment saves $1,788 compared to 12 months of the month-to-month plan (our calculation).

What's included at every Fridays Health tier

Every Fridays plan—month-to-month through 12-month—includes the same support bundle at no extra charge:

  • Unlimited provider visits (captured July 20, 2026)
  • 1-on-1 dietitian support
  • Nutrition and mental-health coaching
  • Care coach
  • Required labs typically include comprehensive metabolic panel, hemoglobin A1C, TSH, and lipid panel
  • Free shipping (captured at checkout)

No membership fee, signup fee, or lab fee is charged (captured July 20, 2026).

PlexusDx tirzepatide pricing (for comparison)

PlexusDx offers compounded tirzepatide injection at three standing rates, all billed monthly with no prepayment requirement and no membership fee:

  • Month-to-month: $289 per month
  • 3-month standing rate: $269 per month
  • 6-month standing rate: $249 per month

Every PlexusDx plan includes medication, provider consultation, free PharmD check-in, and free shipping. An optional genetics add-on is available for $99 for program members (the test does not select or predict medication; a licensed provider decides). PlexusDx works with licensed 503A compounding pharmacies. The same price applies at every dose tier.

Normalized 12-month cost: Fridays vs PlexusDx

The table below compares like-for-like plan structures over 12 months. All Fridays figures are prepaid monthly equivalents (our calculation); all PlexusDx figures are billed monthly with no upfront commitment.

Plan structure Fridays (prepaid) PlexusDx (billed monthly) 12-month difference
Month-to-month $389/mo × 12 = $4,668 $289/mo × 12 = $3,468 PlexusDx saves $1,200
3-month $298.67/mo × 12 = $3,584 $269/mo × 12 = $3,228 PlexusDx saves $356
6-month $275/mo × 12 = $3,300 $249/mo × 12 = $2,988 PlexusDx saves $312
12-month $240/mo × 12 = $2,880 No 12-month tier Fridays wins by $108 vs PlexusDx 6-month rate

All figures are our calculation. Fridays prepaid plans require upfront payment; PlexusDx standing rates are billed monthly with no lock-in.

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Decision factors: What Fridays offers and where gaps exist

Strengths

  • No membership fee, signup fee, or lab fees—the medication price is all-inclusive (captured July 20, 2026).
  • Comprehensive support bundle: unlimited provider visits, 1-on-1 dietitian, nutrition and mental-health coaching, and a dedicated care coach are included in every plan.
  • Lowest effective monthly rate for 12-month commitment: $240 per month (prepaid, our calculation) beats PlexusDx's 6-month rate of $249 by $9 per month if you prepay the full year.
  • 4-for-3 promotional structure: the advertised $224 per month effective rate (our calculation) is the lowest captured, though it requires $896 upfront for four months of medication.
  • Both compounded and branded medication options are available (captured September 4, 2026).

Gaps and uncertainties

  • Month-to-month rate is $100 higher than PlexusDx: $389 vs $289 for tirzepatide on a flexible plan (captured September 4, 2026).
  • Prepaid plans require large upfront commitments: $896 for 3 months, $1,650 for 6 months, $2,880 for 12 months. PlexusDx's standing rates are billed monthly with no lock-in.
  • Pricing conflict in evidence: the pricing summary page advertised $359 per month for tirzepatide (July 20, 2026), while the product checkout page shows $389 (September 4, 2026). Confirm the current rate at checkout.
  • Lowest advertised rates could not be verified: the company profile lists $117 semaglutide and $190 tirzepatide as "lowest advertised" rates, but no other evidence corroborates these figures—they may be promotional landing-page offers that differ from standard checkout pricing.
  • No explicit cancellation or refund policy captured in the evidence.
  • Semaglutide pricing not re-verified: the July 20 pricing page showed $249 per month for semaglutide, but the September 4 product-page dataset includes only tirzepatide plans.

Choose Fridays Health if…

  • You want unlimited provider visits and 1-on-1 dietitian support bundled at no extra charge.
  • You value nutrition and mental-health coaching alongside medication.
  • You are comfortable with a large upfront commitment to secure the lowest effective monthly rate ($240 for 12 months prepaid, or $224 for the 4-for-3 plan).
  • You prioritize a comprehensive support structure over month-to-month flexibility.

Choose PlexusDx if…

  • You want month-to-month flexibility at a lower rate: $289 vs Fridays' $389 for tirzepatide with no lock-in.
  • You prefer standing multi-month rates billed monthly rather than large upfront prepayments ($269 for 3-month, $249 for 6-month).
  • You value transparent, single-price dosing—the same rate applies at every dose tier.
  • You want the option of genetics testing integrated into your program ($99 for members).
  • You want a provider with a verified review record: PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026).

Where PlexusDx fits for tirzepatide

PlexusDx offers compounded tirzepatide injection at $289 per month with no membership fee, no lock-in, and the same price at every dose. The 3-month standing rate ($269 per month) and 6-month standing rate ($249 per month) are both billed monthly—no upfront commitment required. Every plan includes medication, provider consultation, free PharmD check-in, and free shipping. An optional genetics add-on is available for $99 for program members; the test does not select or predict medication, and a licensed provider determines whether a prescription is appropriate.

For patients who prioritize month-to-month flexibility and lower ongoing rates without large prepayments, PlexusDx delivers $1,200 in savings over 12 months compared to Fridays' month-to-month plan (our calculation). For patients willing to commit to 12 months upfront, Fridays' $240 effective monthly rate (our calculation, $2,880 prepaid) offers a $108 annual savings compared to PlexusDx's 6-month rate.

Methodology and freshness

Fridays Health pricing was captured from product pages on the joinfridays.com domain on September 4, 2026 (5 tirzepatide subscription tiers) and from the pricing summary page on July 20, 2026 (membership fees, support inclusions, and semaglutide advertised rate). A pricing conflict exists: the July 20 pricing summary page showed $359 per month for tirzepatide, while the September 4 product checkout page shows $389. We use the more recent product-page figure and advise confirming at checkout. PlexusDx pricing was captured from live product pages on September 7, 2026. All 12-month cost calculations, prepaid monthly equivalents, and savings figures are our calculation. No information was smoothed, extrapolated, or assumed beyond the arithmetic shown. We do not guarantee eligibility, medication selection, dose progression, or uninterrupted service—licensed clinicians make those determinations individually.

Frequently Asked Questions

Does Fridays Health charge a membership fee for tirzepatide?

No. Fridays Health advertises $0 membership fee, $0 signup fee, and $0 lab fees (captured July 20, 2026). The medication price covers unlimited provider visits, 1-on-1 dietitian support, nutrition and mental-health coaching, a care coach, required labs, and free shipping.

What is the lowest monthly cost for Fridays tirzepatide?

The 4-for-3 promotional plan offers an effective rate of $224 per month (our calculation) when you pay $896 upfront for four months of medication (commit to three, receive the fourth free). The 12-month prepaid plan costs $240 per month (our calculation, $2,880 upfront). Both rates are significantly lower than the $389 month-to-month standard rate but require large upfront commitments.

How does Fridays month-to-month tirzepatide pricing compare to PlexusDx?

Fridays charges $389 per month for compounded tirzepatide on a month-to-month plan (captured September 4, 2026). PlexusDx charges $289 per month with no lock-in (captured September 7, 2026). Over 12 months, PlexusDx saves $1,200 compared to Fridays' month-to-month plan (our calculation).

Are Fridays Health's advertised promotional rates the same as the checkout price?

Not always. The company profile notes that "promo landing-page prices differ from product-page standard prices." For example, the pricing summary page advertised $359 per month for tirzepatide (July 20, 2026), while the product checkout page shows $389 (September 4, 2026). Confirm the current rate at checkout before committing.

Does Fridays Health offer semaglutide, or only tirzepatide?

Fridays offers both compounded semaglutide and compounded tirzepatide, as well as branded options (captured September 4, 2026). The July 20, 2026 pricing page advertised semaglutide at $249 per month, but this rate was not re-verified in the September product-page dataset. Confirm current semaglutide pricing at checkout.

Sources

  • Fridays Health product pages (joinfridays.com), accessed September 4, 2026
  • Fridays Health pricing summary page (joinfridays.com/pricing), accessed July 20, 2026
  • Fridays Health company profile, accessed September 4, 2026
  • PlexusDx product pages (plexusdx.com), accessed September 7, 2026
  • PlexusDx Trustpilot profile, accessed September 4, 2026

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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