Last reviewed: September 8, 2026 Last updated: September 8, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Hims & Hers advertises compounded semaglutide at $199/month, but that rate requires a six-month prepayment of $1,194 upfront—$2,388 over 12 months. Seven checkout-verified alternatives offer lower month-to-month rates or better annual value: PlexusDx charges $189/month month-to-month ($2,268/year, saving $120 annually); Eden runs $198/month with no contract ($2,376/year, saving $12 annually); Peak Wellness charges $249/month with no long-term commitment ($2,988/year). Found, TrimRx, Embody, and Henry Meds all charge $289–$299/month but carry no six-month prepayment requirement. The lowest verified month-to-month rate is PlexusDx at $189; the lowest advertised prepaid rate is Found's 12-month cash-pay plan at $169/month prepaid equivalent (paid upfront). Hims & Hers' service quality—backed by 10,094 Trustpilot reviews at 3.7 stars and a large-scale prescription fulfillment infrastructure—remains a competitive strength, but the upfront cost and six-month lock-in create meaningful cash-flow friction for anyone evaluating purely on price or flexibility.

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At-a-glance: verified semaglutide pricing (month-to-month)

Provider Monthly Rate Upfront Commitment 12-Month Cost Captured
PlexusDx $189 $0 (month-to-month) $2,268 Jul 17–23, 2026
Eden $198 $0 (month-to-month) $2,376 Jul 17–23, 2026
Hims & Hers $199
(prepaid equivalent)
$1,194 (6-month prepay) $2,388 Sep 4, 2026
Peak Wellness $249 $0 (month-to-month) $2,988 Jul 17–23, 2026
Found (cash pay) $289 $0 (month-to-month) $3,468 Jul 17–23, 2026
Henry Meds $297 $0 (month-to-month) $3,564 Jul 17–23, 2026
TrimRx $299
(checkout-verified)
$0 (month-to-month) $3,588 Jul 17–23, 2026
Embody $299 $0 (month-to-month) $3,588 Jul 17–23, 2026

Note: Eden's $198/month is the sum of $99 medication plus a required $99/month membership. TrimRx advertised $199/month on its pricing page but charged $299 at checkout (verified July 17–23, 2026). All figures are for compounded semaglutide injection; 12-month costs are our calculation. Confirm current pricing at each provider's checkout before committing.

Hims & Hers' prepaid structure: what the upfront commitment means

Hims & Hers advertises compounded semaglutide at $199/month, but that rate is available only as a six-month prepaid plan requiring $1,194 upfront (captured September 4, 2026). The effective monthly rate over six months is $199; over 12 months (two six-month cycles), the total cost is $2,388, or $199/month on average. The structure bundles medication and clinical access with no separate membership fee, but it locks you into six months of service and requires the full payment at sign-up. If your insurance changes, your side-effect profile shifts, or you decide to switch providers in month two, you've already paid for the full six months.

No verified data is available for Hims & Hers' tirzepatide or branded medication (Wegovy, Ozempic, Zepbound, Mounjaro) pricing at checkout; their site notes that eligibility and dose may affect the advertised offer. If you're considering tirzepatide or a branded option, confirm the total cost and contract term at checkout before committing.

Lower month-to-month rates: PlexusDx and Eden

PlexusDx charges $189/month for compounded semaglutide injection on a month-to-month basis—$2,268 over 12 months, saving $120 annually compared to Hims & Hers' six-month prepaid cycle (our calculation, verified July 17–23, 2026). The rate is the same at every dose; there is no membership fee, no upfront prepayment, and no minimum contract term. Multi-month commitments lower the per-month rate further: a three-month plan runs $169/month, and a six-month plan runs $149/month (all prices month-to-month or prepaid-equivalent).

Eden charges $198/month month-to-month ($2,376 over 12 months, saving $12 annually vs. Hims & Hers; our calculation). The structure separates medication ($99) from a required membership ($99/month), but both are billed together and carry no long-term contract. Eden's advantage is flexibility: you can pause or cancel anytime without forfeiting a prepaid block.

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Other verified month-to-month options

Peak Wellness charges $249/month for compounded semaglutide injection ($2,988 over 12 months; our calculation), with no upfront commitment and lower per-month rates on six-month prepaid plans (verified July 17–23, 2026). Henry Meds charges $297/month ($3,564 over 12 months; our calculation) on a single subscription that includes medication, shipping, and provider access—no separate membership fee. TrimRx advertised $199/month on its pricing page but charged $299/month at checkout during our July 2026 verification ($3,588 over 12 months; our calculation); the discrepancy was consistent across multiple test checkouts. Embody charges $299/month with no membership fee and the same price at every dose ($3,588 over 12 months; our calculation).

Found offers two tracks: a cash-pay month-to-month plan starting at $289/month for semaglutide ($3,468 over 12 months; our calculation), and a 12-month prepaid cash-pay plan starting at $169/month prepaid equivalent (paid upfront, $2,028 over 12 months; our calculation). Found also operates an insurance track starting at $199/month (month-to-month) or $99/month prepaid equivalent (12-month prepaid plan, paid upfront), though pricing varies based on medication, insurance, and coverage. If your insurance covers GLP-1s and Found is in-network, the insurance track may offer the lowest out-of-pocket cost in this comparison.

Tirzepatide pricing: where we have verified data

We have no verified checkout data for Hims & Hers tirzepatide as of September 4, 2026. Among the alternatives, PlexusDx charges $289/month month-to-month for compounded tirzepatide injection ($3,468 over 12 months; our calculation), with no membership fee and the same price at every dose. Eden charges $298/month ($99 medication + $199 membership; $3,576 over 12 months; our calculation). Peak Wellness charges $349/month month-to-month ($4,188 over 12 months; our calculation). Embody charges $349/month month-to-month ($4,188 over 12 months; our calculation). TrimRx advertised $349/month but charged $399/month at checkout ($4,788 over 12 months; our calculation). Found's cash-pay tirzepatide starts at $359/month month-to-month ($4,308 over 12 months; our calculation) or lower on prepaid plans. Henry Meds lists tirzepatide only as an oral dissolving tablet—not an injection—making it non-comparable to the injectable rates above; no monthly rate was published for the oral option during our July 2026 capture.

Service quality and review evidence

Hims & Hers holds a 3.7-star rating on Trustpilot with 10,094 reviews (captured September 4, 2026). The volume and average rating reflect a large-scale prescription fulfillment operation; individual reports on Trustpilot and Reddit describe both smooth experiences and occasional delays, with some anecdotes citing long wait times for customer support or prescription adjustments. The breadth of reviews suggests that most customers receive medication as expected, but a minority report friction around communication or refill timing.

PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026). Eden, Peak Wellness, TrimRx, Embody, Henry Meds, and Found each operate at smaller scale than Hims & Hers; we have no systematic review evidence for those providers as of this publication. If service responsiveness, same-dose guarantee, or flexible cancellation terms matter as much as price, request specifics from each provider during intake.

Choose Hims & Hers if…

You want a large-scale provider with a well-documented track record (10,094 Trustpilot reviews), you're comfortable with a $1,194 upfront commitment for six months, and you value the breadth of options (compounded semaglutide, tirzepatide, and branded medications under one roof). Hims & Hers' infrastructure supports high prescription volume, and the prepaid structure may suit anyone who prefers locking in a rate and not thinking about monthly bills. If cash flow is tight or you want the option to pause after one or two months, the upfront cost and six-month term create friction.

Choose PlexusDx if…

You want the lowest verified month-to-month rate for compounded semaglutide ($189/month, $10/month less than Hims & Hers' prepaid equivalent, $120/year savings over 12 months), no upfront prepayment, and the flexibility to cancel anytime. PlexusDx charges the same price at every dose, includes shipping and provider access, and offers lower per-month rates on three-month ($169/month) and six-month ($149/month) commitments if you're ready for a longer term. The 4.3-star Trustpilot rating (79% five-star, 83% four-star or higher) and straightforward pricing model suit anyone who wants transparency and predictable costs.

Choose Eden if…

You want month-to-month flexibility at $198/month ($1/month more than Hims & Hers' prepaid equivalent over 12 months, $12/year savings annually) with no long-term contract and a membership structure that separates medication from clinical access. Eden's model suits anyone who values the ability to pause or cancel without forfeiting a prepaid block, and the $99 medication + $99 membership split may simplify budgeting.

Choose Peak Wellness, TrimRx, Embody, Henry Meds, or Found if…

You're evaluating providers beyond the lowest-cost options and want month-to-month access without a six-month prepayment. Peak Wellness charges $249/month with no upfront commitment and offers lower per-month rates on six-month prepaid plans. Henry Meds charges $297/month on a single subscription with no separate membership fee. TrimRx charges $299/month at checkout (despite advertising $199/month; confirm the total at checkout). Embody charges $299/month with no membership and the same price at every dose. Found's cash-pay month-to-month plan starts at $289/month for semaglutide, but its insurance track may deliver the lowest out-of-pocket cost if your plan covers GLP-1s and Found is in-network—confirm eligibility during intake. Found's 12-month prepaid cash-pay plan (starting at $169/month prepaid equivalent, paid upfront) is the lowest advertised prepaid rate in this comparison.

Methodology and freshness

This comparison uses checkout-verified pricing for Hims & Hers captured September 4, 2026, and checkout-verified pricing for PlexusDx, Eden, Embody, Found, Henry Meds, Peak Wellness, and TrimRx captured July 17–23, 2026. We recorded the final checkout total for each provider's month-to-month compounded semaglutide plan; where advertised rates differed from checkout totals (TrimRx), we report both and note the discrepancy. All 12-month cost calculations and annual savings figures are our calculation (monthly rate × 12) and are labeled as such. Prepaid-equivalent monthly rates (Hims & Hers' $199/month, Found's $169/month and $99/month) are calculated by dividing the total prepaid cost by the number of months in the commitment and are labeled as prepaid equivalents. Review data for Hims & Hers (Trustpilot 10,094 reviews, 3.7 stars) and PlexusDx (Trustpilot 4.3 stars, 79% five-star, 83% four-star or higher) was captured September 9, 2026. We have no verified checkout data for Hims & Hers' tirzepatide, branded medications, or month-to-month plans as of this publication; readers should confirm those figures at checkout. Henry Meds' tirzepatide is offered only as an oral dissolving tablet, not an injection, and is excluded from injectable tirzepatide comparisons. Pricing and terms may change; confirm current rates at each provider's checkout before committing.

Frequently Asked Questions

Does Hims & Hers offer a month-to-month plan for compounded semaglutide?

We have no verified checkout data for a Hims & Hers month-to-month plan as of September 4, 2026. The advertised $199/month rate requires a six-month prepayment of $1,194 upfront. If you need month-to-month flexibility, PlexusDx ($189/month) and Eden ($198/month) offer verified month-to-month rates with no long-term contract.

What is the lowest verified month-to-month rate for compounded semaglutide?

PlexusDx at $189/month, verified July 17–23, 2026. Eden charges $198/month month-to-month, and Hims & Hers' prepaid equivalent is $199/month over six months (requiring $1,194 upfront). The lowest advertised prepaid rate is Found's 12-month cash-pay plan at $169/month prepaid equivalent, paid upfront.

How much do I save by choosing PlexusDx over Hims & Hers?

$10/month or $120 over 12 months (our calculation), comparing PlexusDx's $189/month month-to-month rate to Hims & Hers' $199/month six-month prepaid equivalent. PlexusDx also carries no upfront prepayment and no minimum contract term, so you can cancel anytime without forfeiting a prepaid block.

Does Hims & Hers offer tirzepatide, and what does it cost?

Hims & Hers lists compounded tirzepatide and branded Zepbound/Mounjaro as available options, but we have no verified checkout pricing as of September 4, 2026. Confirm the total cost, contract term, and upfront prepayment requirement at checkout before committing. PlexusDx charges $289/month month-to-month for compounded tirzepatide injection with no membership fee.

Why did TrimRx charge $299/month at checkout when the pricing page said $199?

We observed a consistent discrepancy during our July 17–23, 2026 verification: TrimRx's pricing page advertised $199/month for semaglutide, but the checkout total was $299/month. The advertised rate may apply to a different plan or require a multi-month commitment; confirm the final total at checkout and ask customer support for clarification if the figures don't match.

Sources

  • PlexusDx internal pricing verification (semaglutide, tirzepatide, month-to-month and multi-month plans), captured July 17–23, 2026
  • Hims & Hers checkout verification (compounded semaglutide six-month prepaid plan, $1,194 upfront), captured September 4, 2026
  • Hims & Hers site review (branded and tirzepatide options listed, checkout pricing not verified), captured September 4, 2026
  • Eden, Embody, Found, Henry Meds, Peak Wellness, TrimRx checkout verification (compounded semaglutide and tirzepatide month-to-month plans), captured July 17–23, 2026
  • Trustpilot reviews: Hims & Hers (10,094 reviews, 3.7 stars), PlexusDx (4.3 stars, 79% five-star, 83% four-star or higher), captured September 9, 2026
  • Reddit anecdotal reports (Hims & Hers customer support and refill timing), reviewed September 4, 2026

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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