Last reviewed: September 2, 2026
Last updated: September 2, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
The short answer
For patients stable at 1.7 mg weekly semaglutide or higher, month-to-month costs range from $189/mo month-to-month (PlexusDx) to $299 across six U.S. compounded programs captured September 2, 2026. PlexusDx, Eden, and Peak Wellness offer the lowest ongoing monthly rates. Found and Henry Meds publish prepaid totals spanning six to twelve months that reduce total outlay but eliminate the flexibility to pause or adjust dose without financial penalty. Eden requires a separate $99/month membership in addition to medication cost. Every program uses the same compounded semaglutide; higher doses do not trigger higher prices at any of the six, but availability of doses above 2.4 mg weekly varies by provider policy and is not guaranteed. Patients who expect to need dose titration or pauses during maintenance favor month-to-month billing; patients certain of stable dosing over six or twelve months favor prepaid totals where offered.
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At-a-glance comparison: six semaglutide programs
| Provider |
Month-to-Month Rate |
Membership Fee |
Formats |
Prepaid Plans |
Cancellation |
| PlexusDx |
$189 |
None |
Injectable, oral |
3-mo, 6-mo available |
Anytime on MTM |
| Eden |
$99 medication + $99 membership = $198 |
$99/month required |
Injectable only |
None |
Anytime |
| Peak Wellness |
$249†
|
None |
Injectable only |
$597 (3-mo), $990 (6-mo) |
Anytime; prepaid refund terms not captured |
| Found |
$289 |
None |
Injectable only |
$8,112 (12-mo), other multi-month available |
Anytime in app |
| Embody |
$299 |
None |
Injectable only |
None published |
Anytime |
| TrimRx |
$299‡
|
None |
Injectable only |
$748 (3-mo), $1,268 (6-mo), $2,218 (12-mo) |
Anytime; prepaid packages not refunded |
| Henry Meds |
$297 injectable $249 oral |
None |
Injectable, oral |
$1,482 (6-mo), $2,364 (12-mo) injectable |
Anytime; may owe remaining balance on prepaid |
†Peak Wellness homepage advertises a lower figure but checkout flow captured July 20, 2026 showed $249 month-to-month. Confirm at checkout.
‡TrimRx homepage advertises $199/month semaglutide; checkout flow captured July 18, 2026 billed $299. Confirm at checkout.
All prices captured September 2, 2026. Membership and medication costs shown separately where applicable. Prepaid totals are as published by each provider.
Normalized month-to-month pricing and 12-month cost
The following table presents like-for-like month-to-month rates and our calculation of total cost over twelve months at each provider's ongoing rate.
| Provider |
Month-to-Month Rate |
12-Month Cost (Our Calculation) |
Notes |
| PlexusDx |
$189 |
$2,268 |
Injectable semaglutide MTM |
| Eden |
$198 ($99 + $99) |
$2,376 |
Medication + required membership |
| Peak Wellness |
$249 |
$2,988 |
Checkout-verified rate; homepage advertises lower figure |
| Found |
$289 |
$3,757 |
Billed every 4 weeks = 13 charges/year |
| Henry Meds (injectable) |
$297 |
$3,564 |
Month-to-month injectable |
| Embody |
$299 |
$3,588 |
Single flat rate |
| TrimRx |
$299 |
$3,588 |
Checkout-verified rate; homepage advertises lower figure |
12-month cost is our calculation (month-to-month rate × 12, or × 13 for Found's 4-week billing cycle). Found charges every 4 weeks rather than calendar monthly, yielding 13 billing events per year. All other programs bill calendar monthly.
Prepaid totals
Four programs publish prepaid totals for patients willing to commit three, six, or twelve months upfront. These totals are billed in full at the start of the commitment period:
-
TrimRx: $748 (3-mo), $1,268 (6-mo), $2,218 (12-mo) semaglutide
-
Peak Wellness: $597 (3-mo), $990 (6-mo) semaglutide
-
Found: $8,112 (12-mo) semaglutide, billed every 48 weeks; other multi-month plans available
-
Henry Meds: $1,482 (6-mo), $2,364 (12-mo) injectable semaglutide
TrimRx states prepaid packages will not be refunded for unused medication or remaining months; cancellation stops future charges only. Henry Meds states multi-month plan members may be required to pay the remaining balance unless unable to continue for medical reasons. Peak Wellness and Found refund policies for unused prepaid months were not captured. Confirm refund terms at checkout before committing to any prepaid plan.
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Decision factors for higher-dose patients
Same price at every dose
All six programs charge the same monthly rate regardless of dose. A patient at 0.25 mg weekly pays the same as a patient at 2.4 mg weekly. This is standard across U.S. compounded-semaglutide telehealth; the medication is the same compound at different concentrations, and the clinical labor of prescribing and shipping does not vary by dose.
Maximum dose availability
The FDA-approved branded semaglutide ceiling is 2.4 mg weekly. Compounded semaglutide is not FDA-approved, and some providers have prescribed doses above 2.4 mg weekly on an individualized basis. None of the six programs publish a maximum-dose guarantee. A licensed clinician determines whether a prescription above 2.4 mg is appropriate for an individual patient; requests for doses above the branded ceiling are not automatically approved and depend on clinical judgment, tolerance history, and the provider's internal protocols. Patients currently stable above 2.4 mg should confirm dose availability with the program's clinical team before enrollment.
Flexibility to pause or reduce dose
Month-to-month billing allows patients to pause treatment or reduce dose mid-month without financial penalty beyond the current billing cycle. Prepaid totals eliminate this flexibility: TrimRx and Henry Meds state explicitly that unused months or doses are not refunded. Found and Peak Wellness refund terms for prepaid plans were not captured. Patients who anticipate needing to pause for surgery, illness, or side-effect management favor month-to-month terms. Patients certain of stable dosing over six or twelve months may accept the loss of flexibility in exchange for the lower prepaid total.
Oral vs. injectable format
PlexusDx and Henry Meds offer both injectable and oral compounded semaglutide. Injectable semaglutide is administered subcutaneously once weekly. Oral semaglutide (sublingual tablets at Henry Meds, capsules at PlexusDx) is taken daily. The oral formulations are compounded and not FDA-approved; bioavailability and clinical outcomes data for compounded oral semaglutide are limited compared to the extensive published evidence for injectable semaglutide. Patients who have achieved stable weight loss on injectable semaglutide and wish to avoid needles long-term may consider oral formats, but switching from injectable to oral may require dose retitration and is a clinical decision made by the prescribing provider. Eden, Embody, Found, Peak Wellness, and TrimRx offer injectable semaglutide only.
Membership fees
Eden bills medication and membership separately: $99/month medication plus $99/month required membership, totaling $198/month. The membership is mandatory and recurs as long as the medication subscription is active. The other five programs charge a single all-inclusive monthly rate with no separate membership fee. Patients should account for the combined $198/month Eden cost when comparing.
Billing cadence: calendar month vs. 4-week cycle
Found bills every four weeks rather than calendar monthly, resulting in thirteen charges per year instead of twelve. At $289 per charge, twelve months of Found semaglutide costs $3,757 (our calculation: $289 × 13). The other five programs bill calendar monthly, yielding twelve charges per year. This difference is material when calculating annual cost.
Support and care-team access
Embody includes 24/7 clinical chat support and unlimited provider visits in its $299/month rate. Found includes 24/7 access to a care team, personalized care plans, and an AI concierge (Aimee) in its app. Peak Wellness includes 24/7 clinical support and priority access. PlexusDx includes a free pharmacist (Dr. Jayden Lee, PharmD) check-in and provider messaging. Eden, Henry Meds, and TrimRx include provider consultations and ongoing access; specifics of after-hours support were not captured. Patients who value around-the-clock live support may weight Embody, Found, and Peak Wellness higher.
Money-back and satisfaction guarantees
Eden offers a weight-loss guarantee: lose 10% body weight in six months or receive a refund on compounded plans; full terms were not captured. Embody offers a six-month satisfaction refund; full terms were not captured. Found offers a full refund if a patient is not clinically eligible. The other three programs' refund policies were not documented beyond cancellation terms. Patients concerned about non-response or side effects should confirm refund eligibility and conditions at enrollment.
Choose PlexusDx if…
- You want the lowest published month-to-month rate ($189) among the six programs.
- You value the option to switch between injectable and oral semaglutide formats without changing providers.
- You prefer a single all-inclusive charge with no separate membership fee.
- You want flexibility to cancel anytime on the month-to-month plan or to lock in a lower rate with a prepaid three- or six-month plan.
- You appreciate access to a licensed pharmacist (Dr. Jayden Lee, PharmD) for medication questions at no additional charge.
Choose Eden if…
- You value a money-back weight-loss guarantee (10% body weight in six months) and are willing to pay $198/month total ($99 medication + $99 membership).
- You prefer month-to-month flexibility with no prepaid commitment.
- You are comfortable with two separate recurring charges (medication and membership) rather than a single all-inclusive bill.
Choose Peak Wellness if…
- You want 24/7 priority clinical support and are willing to pay $249/month month-to-month (verify at checkout; homepage advertises a lower starting figure).
- You are interested in prepaid totals ($597 for three months, $990 for six months) and accept that refund terms for unused months were not captured.
- You prefer knowing which specific 503A compounding pharmacies will fill your prescription (Emerald, Epiq Scripts, Southend, AbsoluteRX).
Choose Found if…
- You want an all-in-one app experience with personalized care plans, 24/7 care-team access, and AI concierge support.
- You are willing to pay $289 every four weeks ($3,757 over twelve months, our calculation) for month-to-month flexibility or commit to a prepaid total ($8,112 for twelve months; other multi-month plans available).
- You value the option to use insurance; Found offers separate insurance-based pricing with copays typically around $30.
Choose Embody if…
- You want unlimited provider visits and 24/7 clinical chat support included in a flat $299/month rate.
- You prefer month-to-month billing with no prepaid commitment.
- You value a six-month satisfaction refund policy (confirm full terms at enrollment).
Choose TrimRx if…
- You are comfortable with $299/month month-to-month (verify at checkout; homepage advertises a lower figure) or are willing to commit to a prepaid total ($748 for three months, $1,268 for six months, $2,218 for twelve months) with the understanding that unused months will not be refunded.
- You want the option of 0% financing through Klarna, Afterpay, or Affirm to spread the prepaid total into installments.
Choose Henry Meds if…
- You want the option to switch between injectable ($297/month month-to-month) and oral sublingual semaglutide ($249/month) within the same program.
- You are willing to commit to a prepaid six- or twelve-month plan ($1,482 or $2,364) with the understanding that you may owe the remaining balance if you cancel early unless unable to continue for medical reasons.
- You are interested in oral tirzepatide or phentermine options in addition to semaglutide (injectable tirzepatide is not offered).
Methodology and freshness
All pricing, plan terms, and program details were captured September 2, 2026 from each provider's public website, checkout flows, or terms of service. PlexusDx comparison captures reflect checkout-verified rates where multi-step signup flows were completed; homepage marketing language was noted separately where it differed from checkout data. Month-to-month rates are published as shown at checkout. Prepaid totals are published as each provider states them. Twelve-month cost calculations are our own arithmetic (month-to-month rate × 12 or × 13 for Found's four-week cycle). Where homepage and checkout pricing differ, readers are advised to confirm at checkout. All programs reviewed offer compounded semaglutide; none is FDA-approved. Availability of doses above 2.4 mg weekly is not guaranteed and depends on individual clinical assessment by a licensed provider.
Frequently Asked Questions
Do higher semaglutide doses cost more per month?
No. All six programs charge the same monthly rate regardless of dose. A patient prescribed 0.5 mg weekly pays the same as a patient prescribed 2.4 mg weekly. The compound and clinical service are identical; only the concentration varies.
Can I get semaglutide above 2.4 mg weekly from these providers?
Possibly, but not guaranteed. The FDA-approved maximum is 2.4 mg weekly. Some compounded-semaglutide providers have prescribed higher individualized doses, but none of the six programs guarantees availability above 2.4 mg. A licensed clinician determines appropriateness on a case-by-case basis. Confirm dose availability with the provider's clinical team before enrolling if you require more than 2.4 mg weekly.
What happens if I need to pause treatment mid-month on a prepaid plan?
Refund terms vary. TrimRx states prepaid packages are not refunded for unused months. Henry Meds may require you to pay the remaining balance unless you cannot continue for medical reasons. Peak Wellness and Found refund policies for prepaid plans were not captured. Month-to-month plans at all six providers allow you to cancel anytime, stopping charges after the current cycle. Confirm refund terms at checkout before committing to any prepaid plan.
Is compounded semaglutide the same as branded prescription semaglutide?
No. Compounded semaglutide contains the same active ingredient (semaglutide) but is not FDA-approved and is not verified by FDA for safety, effectiveness, or quality before marketing. Branded prescription semaglutide products are FDA-approved with established dosing, formulation, and manufacturing standards. A licensed clinician determines whether compounded semaglutide is appropriate for you.
Which provider offers the lowest cost over twelve months?
On month-to-month terms, PlexusDx has the lowest twelve-month cost at $2,268 (our calculation: $189 × 12). Prepaid plans can lower total cost but eliminate flexibility. TrimRx's twelve-month prepaid total is $2,218; Henry Meds' is $2,364; Found's is $8,112. Compare prepaid totals directly, and weigh the loss of flexibility against the cost difference.
Sources
- Source 1: PlexusDx internal comparison – Eden pricing and terms, captured September 2, 2026
- Source 2: PlexusDx internal comparison – Embody pricing and terms, captured September 2, 2026
- Source 3: PlexusDx internal comparison – Found cash-pay pricing and terms, captured September 2, 2026
- Source 4: PlexusDx internal comparison – Found insurance pricing and features, captured September 2, 2026
- Source 5: PlexusDx internal comparison – Henry Meds pricing and formats, captured September 2, 2026
- Source 6: PlexusDx internal comparison – Henry Meds inclusions and cancellation, captured September 2, 2026
- Source 7: PlexusDx internal comparison – Henry Meds microdose offering, captured September 2, 2026
- Source 8: PlexusDx internal comparison – Peak Wellness checkout-verified pricing, captured July 20, 2026
- Source 9: PlexusDx internal comparison – Peak Wellness homepage and pharmacy partners, captured July 20, 2026
- Source 10: PlexusDx internal comparison – TrimRx checkout-verified pricing and refund terms, captured July 18, 2026
- Source 11: PlexusDx internal comparison – TrimRx advertised rates and financing, captured September 2, 2026
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Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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