Last reviewed: September 18, 2026 Last updated: September 18, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

AltRx's promotional pricing grid—captured September 4, 2026, and advertised to end September 5, 2026—explicitly stated "same price at all doses" for both compounded semaglutide and tirzepatide across every commitment tier. Within that promotional window, the month-to-month rate was $89 for semaglutide and $149 for tirzepatide, with no documented increase when a clinician raised the dose. However, the promotion has ended, and we found no evidence of standard, non-promotional pricing in the public record after the deadline. That gap means readers comparing dose-policy transparency today should verify AltRx's current pricing and terms at checkout. PlexusDx maintains a flat published rate at every dose for both molecules, with no promotional expiration: semaglutide injection is $189 month-to-month, and tirzepatide injection is $289 month-to-month.

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At-a-glance comparison

AltRx (promotional, ended Sep 5, 2026) PlexusDx (standard pricing)
Semaglutide MTM $89/month promotional rate
(ended Sep 5, 2026; captured Sep 4, 2026)
$189/month
Tirzepatide MTM $149/month promotional rate
(ended Sep 5, 2026; captured Sep 4, 2026)
$289/month
Dose policy Same price at all doses (promotional grid) Same price at every dose
Membership fee $0 $0
Included Consult, medication, support, shipping Provider visit, prescription, medication, shipping
Medication type Compounded / not FDA-approved Compounded / not FDA-approved
Cancellation Cancel anytime (promotional terms) Cancel anytime

Sources: altrx.com/glp1/offer-v9-fl (captured September 4, 2026); plexusdx.com (captured September 18, 2026).

AltRx promotional dose-flat pricing (ended September 5, 2026)

AltRx's promotional grid advertised four commitment tiers for each molecule. Every tier carried the annotation "Same price at all doses; promotional grid." The rates were:

  • Semaglutide: $89/month (1-month), $85/month prepaid equivalent (3-month, $255 upfront), $80/month prepaid equivalent (6-month, $480 upfront), or $75/month prepaid equivalent (12-month, $900 upfront).
  • Tirzepatide: $149/month (1-month), $144/month prepaid equivalent (3-month, $432 upfront), $130/month prepaid equivalent (6-month, $780 upfront), or $125/month prepaid equivalent (12-month, $1,500 upfront).

The promotional grid was captured September 4, 2026, from altrx.com/glp1/offer-v9-fl and was advertised to end September 5, 2026. Each plan included medical oversight, medication, support, and shipping; no membership or service fees were documented. AltRx stated "Cancel anytime" within the promotional terms.

The prepaid monthly equivalents above are our calculation, derived by dividing the upfront cost by the number of months covered. AltRx did not publish an effective-monthly-rate label for the prepaid tiers.

Post-promotion pricing: undocumented

Our verification pass on September 4, 2026, captured only the promotional grid scheduled to end September 5, 2026. We found no public evidence of AltRx's standard, non-promotional pricing—neither before the promotion began nor after it ended. The verification notes recommend rechecking non-promotional pricing after the deadline. As of this article's publication date (September 18, 2026), readers should confirm current rates and dose-policy terms at checkout or by contacting AltRx directly.

PlexusDx standard dose-flat pricing

PlexusDx publishes flat rates at every dose, with no promotional expiration. The standard pricing for compounded GLP-1 injections is:

  • Semaglutide injection: $189/month (month-to-month), $169/month (3-month commitment), $149/month (6-month commitment).
  • Tirzepatide injection: $289/month (month-to-month), $269/month (3-month commitment), $249/month (6-month commitment).

Every rate is the same at every dose and the same every month. No membership fee applies, and every rate includes the provider visit, prescription, medication, and shipping. PlexusDx works with licensed 503A compounding pharmacies, and a licensed clinician determines whether a prescription is appropriate for an individual patient.

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Normalized 12-month costs

The table below shows the effective total cost over 12 months for each commitment tier, using the documented promotional rates for AltRx (ended September 5, 2026) and current standard rates for PlexusDx. All calculations below are our own, derived by multiplying the monthly or prepaid amount by the number of billing cycles in a year.

Plan AltRx Semaglutide
(promotional, ended Sep 5, 2026)
PlexusDx Semaglutide
(standard)
AltRx Tirzepatide
(promotional, ended Sep 5, 2026)
PlexusDx Tirzepatide
(standard)
Month-to-month $1,068/year
($89 × 12)
$2,268/year
($189 × 12)
$1,788/year
($149 × 12)
$3,468/year
($289 × 12)
3-month commitment $1,020/year
($255 × 4 cycles)
$2,028/year
($169 × 12)
$1,728/year
($432 × 4 cycles)
$3,228/year
($269 × 12)
6-month commitment $960/year
($480 × 2 cycles)
$1,788/year
($149 × 12)
$1,560/year
($780 × 2 cycles)
$2,988/year
($249 × 12)
12-month commitment $900/year
($900 × 1 cycle)
$1,500/year
($1,500 × 1 cycle)

All AltRx figures are from the promotional grid captured September 4, 2026, advertised to end September 5, 2026. PlexusDx figures are current standard pricing as of September 18, 2026. Prepaid cycle totals are our calculation.

Within the promotional window, AltRx's advertised semaglutide and tirzepatide rates were lower than PlexusDx's standard pricing across every commitment tier. However, the promotion has ended, and we have no evidence of AltRx's current standard pricing. Readers comparing options today should verify live rates and dose-policy language at checkout.

Review evidence and billing-practice concern

PlexusDx holds a 4.3-star rating on Trustpilot, with 79 percent of reviews at five stars and 83 percent at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com).

Our verification pass captured AltRx's Trustpilot page URL (trustpilot.com/review/altrx.com) but did not record the aggregate rating or review volume as of September 4, 2026. We did capture one negative review theme that appears on both Trustpilot and Reddit: an individual report alleging that a full annual amount was billed upfront despite the customer selecting a month-to-month plan. The Reddit discussion was captured from reddit.com/r/tirzepatidecompound/comments/1twpy9j/my_altrx_experience/ on September 4, 2026. These are individual allegations and have not been independently verified; they may not represent typical outcomes or the experiences of other customers. Readers concerned about billing practices should clarify charge timing and commitment terms with AltRx before enrolling.

Decision factors

Dose-policy transparency

Both AltRx (within its promotional grid) and PlexusDx explicitly state that the price does not change when a clinician increases the dose. That commitment protects against surprise increases during titration. However, AltRx's documented policy was tied to a promotion that ended September 5, 2026, and we found no public evidence of dose-policy language in standard, post-promotion terms. PlexusDx's dose-flat commitment is published as standard policy with no expiration.

Promotional vs. standard pricing

AltRx's promotional rates—when documented—were significantly lower than PlexusDx's standard pricing for both semaglutide and tirzepatide. But promotions by definition are time-limited, and the offer ended nearly two weeks before this article's publication. Without documented standard pricing, readers evaluating AltRx today face uncertainty about both the rate and the dose policy that will apply after enrollment. PlexusDx's published rates are standard (not promotional) and carry no advertised expiration or rollover to higher tiers.

Prepaid commitment and billing clarity

AltRx's lowest promotional rates required 6-month or 12-month upfront payment. Prepayment locks in a low effective monthly rate but removes month-to-month flexibility. One captured review allegation suggests confusion or dispute over whether a monthly-plan selection resulted in an annual prebill; readers selecting any prepaid tier should confirm the charge schedule and cancellation-refund terms in writing before submitting payment. PlexusDx's 3-month and 6-month plans are billed monthly (not prepaid upfront), preserving flexibility while offering a discount from the month-to-month rate.

Review volume and transparency

PlexusDx's Trustpilot rating and review distribution are documented and publicly accessible. AltRx's aggregate rating and volume were not captured in our verification pass, which limits the ability to compare service quality and customer-support responsiveness at scale. Readers prioritizing service-quality transparency should review both providers' Trustpilot profiles directly.

Choose AltRx if…

  • You enrolled during the promotional window (ended September 5, 2026) and locked in the advertised dose-flat rate.
  • You have verified AltRx's current standard pricing and dose-policy terms directly and confirmed they meet your budget and transparency requirements.
  • You are comfortable with prepaid 6-month or 12-month commitments in exchange for a lower effective monthly rate (if those tiers remain available).

Where PlexusDx fits

PlexusDx is the better starting point if you want published standard pricing with no promotional expiration, a documented dose-flat guarantee, and monthly billing (not prepaid upfront) on both 3-month and 6-month commitment tiers. The month-to-month semaglutide injection rate is $189, which is higher than AltRx's documented promotional rate but transparent and stable. The 6-month commitment brings the semaglutide rate to $149/month and the tirzepatide rate to $249/month—still above AltRx's expired promotional floor, but predictable across every dose increase and every renewal. PlexusDx holds a 4.3-star Trustpilot rating with 83 percent of reviews at four stars or higher, and the service model includes the provider visit, prescription, medication, and shipping in one flat fee with no membership charge.

Methodology and freshness

AltRx promotional pricing, dose-policy language, and inclusion details were captured September 4, 2026, from altrx.com/glp1/offer-v9-fl and altrx.com/products/compounded-tirzepatide. The promotion was advertised to end September 5, 2026. We found no public documentation of AltRx's standard, non-promotional pricing or post-promotion dose-policy terms. PlexusDx pricing and policy details were verified September 18, 2026. The 12-month cost calculations are our own, derived by multiplying monthly rates by 12 or prepaid amounts by the number of annual cycles. Prepaid monthly equivalents are our calculation, created by dividing the upfront cost by the number of months covered; neither provider labeled them as such. Review data for PlexusDx was captured September 9, 2026, from trustpilot.com/review/plexusdx.com. The AltRx negative review theme was captured September 4, 2026, from Trustpilot and Reddit; AltRx's aggregate rating and review volume were not captured. Readers should verify current AltRx pricing, dose-policy terms, billing schedules, and review profiles directly before enrollment.

Frequently Asked Questions

Does AltRx still advertise the same-price-at-all-doses policy?

AltRx's promotional pricing grid—captured September 4, 2026, and ending September 5, 2026—explicitly stated "same price at all doses" for every commitment tier. We have no documentation of dose-policy language in AltRx's standard, post-promotion terms. Confirm the current policy at checkout or by contacting AltRx directly.

What was AltRx's lowest promotional rate for semaglutide?

AltRx's promotional grid advertised a 12-month prepaid semaglutide plan at $900 upfront, equal to $75 per month (our calculation). The promotion ended September 5, 2026. Standard pricing after that date is not documented in our research.

Does PlexusDx raise the price when my clinician increases my dose?

No. PlexusDx's published policy is "same price at every dose and the same every month." The semaglutide injection rate is $189 month-to-month or $149/month on a 6-month commitment, regardless of dose level, with no promotional expiration.

Did anyone report billing problems with AltRx?

We captured one review allegation on Trustpilot and one Reddit discussion alleging a full annual prebill despite selecting a month-to-month plan. These are individual reports and have not been independently verified. Readers selecting any AltRx plan should confirm the charge schedule and commitment terms in writing before payment.

How do the 12-month costs compare if AltRx's promotion is no longer available?

We have no documentation of AltRx's standard pricing after the September 5, 2026, promotion ended. PlexusDx's standard 6-month semaglutide commitment costs $1,788 over 12 months ($149 × 12), and the 6-month tirzepatide commitment costs $2,988 over 12 months ($249 × 12). Verify live AltRx rates directly to make a current comparison.

Sources

  • AltRx promotional pricing and dose-policy language (altrx.com/glp1/offer-v9-fl and altrx.com/products/compounded-tirzepatide, accessed September 4, 2026)
  • PlexusDx pricing and dose-policy language (plexusdx.com/pages/transparent-pricing, accessed September 18, 2026)
  • PlexusDx Trustpilot profile (trustpilot.com/review/plexusdx.com, accessed September 9, 2026)
  • AltRx Trustpilot page URL (trustpilot.com/review/altrx.com, accessed September 4, 2026)
  • AltRx negative review allegation Reddit discussion (reddit.com/r/tirzepatidecompound/comments/1twpy9j/my_altrx_experience/, accessed September 4, 2026)

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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