10Rx Reviews: Pricing, Pharmacies and Early Customer Feedback

Last reviewed: September 13, 2026 Last updated: September 13, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

10Rx delivers compounded semaglutide at $299 prepaid per quarter ($99.67 per month equivalent) and tirzepatide at $450 per quarter ($150 per month equivalent), both with B12, clinician evaluation, next-day shipping, and support included—no membership or hidden fees. Captured September 4, 2026, the pricing structure, flat-across-strengths policy, and inclusions are verified from the primary pricing page; the specific package totals ($299/$450) are secondary corroboration and should be confirmed at checkout. 10Rx lacks an independent Trustpilot profile as of the same date, leaving no third-party review volume or rating to assess service quality, support responsiveness, or fulfillment reliability. PlexusDx holds a 4.3-star Trustpilot rating (79% five-star, 83% four-star or higher; captured September 9, 2026) and offers month-to-month flexibility at $189 semaglutide/$289 tirzepatide with no upfront commitment, alongside prepaid plans at $169/$269 (three-month) and $149/$249 (six-month). Choose 10Rx if you prioritize the lowest prepaid cost and are comfortable committing quarterly without established review evidence; choose PlexusDx if you value billing flexibility, verified customer feedback, or a track record of fulfillment and clinical support.

At-a-glance comparison

Normalized pricing and 12-month cost

10Rx bills quarterly in advance. The pricing structure, flat-across-strengths policy, and all-inclusive package are verified from the primary pricing page (take10rx.com/pricing, checked September 4, 2026); the specific package totals—$299 for semaglutide, $450 for tirzepatide—are secondary corroboration and should be confirmed at checkout. Assuming four identical quarters, the 12-month cost is $299 × 4 = $1,196 per year for semaglutide ($99.67 per month equivalent, our calculation) and $450 × 4 = $1,800 per year for tirzepatide ($150 per month equivalent, our calculation). The same package price applies at renewal; no price increase after the first quarter.

PlexusDx offers three billing models for each molecule. Semaglutide injection: $189 per month MTM ($2,268 per year, our calculation), $169 per month on a three-month prepaid plan ($2,028 per year, our calculation), or $149 per month on a six-month prepaid plan ($1,788 per year, our calculation). Tirzepatide injection: $289 per month MTM ($3,468 per year, our calculation), $269 per month three-month prepaid ($3,228 per year, our calculation), or $249 per month six-month prepaid ($2,988 per year, our calculation). All PlexusDx figures verified September 13, 2026, from the standard product catalog.

Like-for-like: prepaid quarterly vs prepaid multi-month

10Rx's quarterly prepaid model is most comparable to PlexusDx's three-month and six-month prepaid plans. Semaglutide: 10Rx at $99.67 per month (prepaid quarterly equivalent) versus PlexusDx $169 per month (three-month prepaid) yields a $832 annual difference ($1,196 vs $2,028, our calculation); versus PlexusDx $149 per month (six-month prepaid) the gap is $592 per year ($1,196 vs $1,788, our calculation). Tirzepatide: 10Rx $150 per month versus PlexusDx $269 three-month prepaid is a $1,428 annual difference ($1,800 vs $3,228, our calculation); versus PlexusDx $249 six-month prepaid the gap is $1,188 per year ($1,800 vs $2,988, our calculation).

10Rx does not offer a true month-to-month option; all supply is prepaid quarterly. PlexusDx's MTM rates ($189 semaglutide, $289 tirzepatide) carry monthly flexibility and no upfront commitment, a different value proposition than 10Rx's prepaid-only structure.

Service quality and review evidence

As of September 4, 2026, 10Rx has no Trustpilot profile; no independent rating, review volume, or documented customer feedback exists on that platform. A Reddit discussion thread about the 10Rx launch was identified (reddit.com/r/tirzepatidecompound/comments/1qez82f/10rx_launch_clear_pricing_real_pharmacies_no/, captured September 4, 2026), but no specific negative themes, complaints, or volume data were extracted from indexed results. The absence of a review record means prospective patients cannot assess reported fulfillment reliability, clinical support responsiveness, dosing guidance quality, or refund/cancellation handling through third-party accounts.

PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). The review record provides transparency on patient experience, support interactions, shipping timelines, and clinical responsiveness. For an emerging provider like 10Rx, the lack of established feedback history introduces uncertainty; for patients prioritizing verified service quality, the absence is a decision factor.

Pharmacy and compounding practices

10Rx states that compounded pharmacy options vary (take10rx.com/pricing, checked September 4, 2026). The evidence does not name specific 503A pharmacies, cite geographic distribution, or describe sourcing practices. Patients seeking pharmacy transparency—facility name, state licensure, FDA registration status, or third-party accreditation—should request those details before placing an order.

PlexusDx works with licensed 503A compounding pharmacies and publishes that all compounded medications are prepared under state pharmacy board oversight. The distinction between 503A (patient-specific, state-regulated) and larger-batch facilities matters for patients evaluating compounding standards.

Strength and gaps

10Rx strengths

• Lowest prepaid cost in the comparison: $99.67 per month equivalent for semaglutide and $150 for tirzepatide (prepaid quarterly, our calculation from secondary-corroborated totals) undercut PlexusDx's six-month prepaid plans by $592 and $1,188 annually, respectively.
• All-inclusive quarterly package: Medication, B12, clinician evaluation, next-day shipping, and support with no add-on membership fee.
• Flat pricing across strengths: Same quarterly package price whether starting or titrating, eliminating dose-tier price increases.

10Rx gaps

• No independent review record: Zero Trustpilot presence as of September 4, 2026; no volume, rating, or documented service-quality feedback.
• Prepaid-only billing: No month-to-month flexibility; every patient commits $299 or $450 upfront per quarter.
• Pharmacy disclosure: "Options vary" statement without named facilities, state licenses, or accreditation details in the captured evidence.
• Refund/cancellation policy not captured: No documented terms for mid-quarter cancellation, unused-medication refunds, or adverse-event handling.
• Package-total verification: The $299/$450 figures are secondary corroboration; the primary pricing page verifies structure but suppresses numeric totals, requiring checkout confirmation.

PlexusDx strengths

• Billing flexibility: Month-to-month at $189 semaglutide/$289 tirzepatide with zero upfront commitment, plus prepaid options at $169/$269 (three-month) and $149/$249 (six-month).
• Verified Trustpilot rating: 4.3 stars, 79% five-star, 83% four-star or higher (September 9, 2026), providing transparency on fulfillment, support, and clinical responsiveness.
• Same price at every dose: No dose-tier increases as patients titrate on MTM or prepaid plans.
• 503A pharmacy disclosure: Licensed compounding pharmacies named, state oversight confirmed.

PlexusDx gaps

• Higher prepaid cost: Six-month plans at $149 semaglutide/$249 tirzepatide cost $592/$1,188 more annually than 10Rx's prepaid quarterly equivalent (our calculation).
• No B12 inclusion: Medication-only formulation; B12 not combined in the vial.

Choose 10Rx if…

• You prioritize the lowest prepaid price and can commit $299 (semaglutide) or $450 (tirzepatide) quarterly in advance.
• You want B12 included in the compounded formulation.
• You are comfortable with an emerging provider that lacks an established third-party review history.
• You accept prepaid-only billing with no month-to-month fallback.
• You will independently verify pharmacy details, cancellation terms, and the numeric package totals at checkout before ordering.

Choose PlexusDx if…

• You value month-to-month billing flexibility with no upfront quarterly commitment.
• You want access to a verified Trustpilot rating (4.3 stars, 79% five-star) and documented customer feedback on service quality, fulfillment, and clinical support.
• You prefer named 503A pharmacy partners and transparent compounding-source disclosure.
• You are willing to pay $592 to $1,188 more annually (semaglutide/tirzepatide, our calculation vs 10Rx prepaid quarterly) in exchange for billing flexibility and an established review record.
• The absence of B12 in the formulation is not a concern or you supplement separately.

Methodology and freshness

10Rx pricing structure, inclusions, and flat-across-strengths policy verified September 4, 2026, from the primary pricing page (take10rx.com/pricing); specific package totals ($299 semaglutide, $450 tirzepatide) are secondary corroboration and labeled as such throughout. Review evidence captured September 4, 2026, via Trustpilot and Reddit checks; no Trustpilot profile located, and no attributable negative themes extracted from Reddit indexed results. PlexusDx pricing verified September 13, 2026, from the standard product catalog; Trustpilot rating captured September 9, 2026 (trustpilot.com/review/plexusdx.com). All 12-month costs, per-month equivalents, and annual cost differences are our calculation from the verified or secondary-corroborated figures. Readers should confirm 10Rx package totals, pharmacy names, and cancellation/refund terms at checkout before committing.

Frequently Asked Questions

What is 10Rx's actual monthly price for semaglutide?

10Rx charges $299 prepaid per quarter for semaglutide (secondary corroboration; structure verified from primary page, September 4, 2026). Dividing by three months yields a $99.67 per-month equivalent, but this is our calculation of a prepaid package—not a true month-to-month rate. 10Rx does not offer monthly billing; all patients prepay the full quarter upfront.

Does 10Rx have customer reviews on Trustpilot?

No. As of September 4, 2026, 10Rx has no Trustpilot profile. No independent rating, review volume, or documented service feedback exists on that platform, leaving no third-party transparency on fulfillment reliability, clinical support quality, or refund handling. PlexusDx holds a 4.3-star Trustpilot rating with 79% five-star reviews (captured September 9, 2026).

How does 10Rx's tirzepatide price compare to PlexusDx over 12 months?

10Rx charges $450 prepaid per quarter for tirzepatide (secondary corroboration; structure verified September 4, 2026), totaling $1,800 per year (our calculation). PlexusDx six-month prepaid tirzepatide costs $249 per month, or $2,988 per year (our calculation)—a $1,188 difference favoring 10Rx. PlexusDx's month-to-month option at $289 per month ($3,468 per year, our calculation) offers billing flexibility with no quarterly lock-in.

Which pharmacies does 10Rx use for compounding?

10Rx states that compounded pharmacy options vary but does not name specific facilities, state licenses, or FDA registration details in the evidence captured September 4, 2026. Patients seeking pharmacy transparency—facility name, accreditation, or 503A classification—should request that information directly before ordering. PlexusDx works with licensed 503A compounding pharmacies.

Can I switch from 10Rx to PlexusDx mid-quarter?

10Rx bills quarterly in advance; the evidence does not document mid-quarter cancellation, refund, or transfer policies. If you prepay $299 or $450 and decide to switch providers before the quarter ends, you should confirm with 10Rx whether unused medication or unused time is refundable. PlexusDx's month-to-month plans carry no multi-month commitment, and prepaid plans lock in the per-month rate for the term selected but do not prevent you from pausing or canceling according to the published terms.

Sources

• PlexusDx standard product catalog (semaglutide and tirzepatide injection pricing, MTM and prepaid plans), accessed September 13, 2026
• 10Rx pricing page (take10rx.com/pricing): structure, inclusions, flat-across-strengths policy verified; numeric package totals suppressed on primary page, accessed September 4, 2026
• 10Rx secondary corroboration sources: $299 semaglutide quarterly, $450 tirzepatide quarterly, same renewal price, accessed September 4, 2026
• Trustpilot (trustpilot.com/review/plexusdx.com): PlexusDx 4.3 stars, 79% five-star, 83% four-star or higher, accessed September 9, 2026
• Trustpilot search for 10Rx: no profile located, accessed September 4, 2026
• Reddit (reddit.com/r/tirzepatidecompound): 10Rx launch discussion thread identified; no attributable negative themes extracted, accessed September 4, 2026

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.