Autoimmune Paleo (AIP) Diet

The Autoimmune Paleo (AIP) Diet is a specialized nutritional therapy designed to reduce inflammation, support the healing of the intestinal lining (often referred to as "leaky gut"), and manage autoimmune conditions. This comprehensive 7-day meal plan strictly adheres to the Autoimmune Paleo Protocol, meaning it is autoimmune-compliant, gluten-free, dairy-free, egg-free, grain-free, and nightshade-free. By eliminating these common immune stimulants—along with refined sugars, industrial oils, nuts, seeds, and food additives—the diet aims to remove potential triggers that may overactivate your immune system. This approach directly aligns with insights from your PlexusDx report, specifically addressing genes like TNF, IL6, and IL1B, which play central roles in regulating your body's inflammatory response. Additionally, by excluding gluten and histamine-triggering foods, this plan supports pathways influenced by HLA variants and the AOC1 gene, helping to calm digestive irritation and support systemic immune balance.

This program is built on evidence-based strategies to restore gut barrier integrity and regulate the immune system through nutrient density rather than just restriction. The meal plan focuses on dampening oxidative stress and supporting liver detoxification, which is critical for hormone regulation. Key evidence-backed recommendations for this protocol include:

Maximize Polyphenols: Eat plenty of broccoli, spinach, carrots, and extra virgin olive oil to help control oxidative stress and inflammation.
Support Gut Health: Combine prebiotic foods like garlic and apples with fermented options like sauerkraut to feed beneficial bacteria and restore microbiome balance.
Regulate Hormones: Prioritize healthy fats and cruciferous vegetables (cabbage, cauliflower, kale) to provide indoles that support liver detoxification and cortisol balance.
Boost Immune Function: Ensure adequate intake of Vitamin A from sweet potatoes and carrots, Vitamin C from Brussels sprouts, and Zinc from quality meats to strengthen immune defense.

Click the button below to access your personalized PlexusDx meal planning tool. If you need to adjust any meals to better fit your taste preferences while staying compliant, follow these steps:

Locate the meal you wish to change on your daily planner.
Click the three dots next to the meal name.
Select "Swap recipe" from the dropdown menu.
Choose "Swap" to change just that meal, or "Swap all" to replace it for the week.
Keep clicking "Swap" to cycle through alternatives that automatically match your plan's strict rules (e.g., GF, DF, nightshade-free).

PlexusDx provides educational information about genetic predispositions only. This content is not medical advice. Always discuss genetic findings, test results, symptoms, and treatment decisions with your healthcare provider or an allergist to determine appropriate care for your situation.

Meal Planning Tool ➜

Diets & Meal Plans