Autoimmune Keto Diet

The Autoimmune Keto Diet combines the principles of an autoimmune protocol with a ketogenic approach to lower inflammation and support immune balance. By restricting carbohydrates to under 25 grams of net carbs daily, this plan minimizes blood sugar fluctuations while simultaneously removing common immune triggers found in standard diets. This specialized meal plan is designed to be gluten-free, grain-free, dairy-free, and egg-free, ensuring that you adhere to a strict elimination phase that avoids nightshades, legumes, nuts, and seeds. This approach is particularly relevant if your PlexusDx report identifies variations in inflammation-regulating genes like TNF, IL6, and CRP, which control how your body signals and resolves inflammatory responses. Additionally, because the diet emphasizes nutrient-dense, low-toxin foods, it supports pathways related to gut defense and detoxification, relevant to genes such as IL23R and ABCC2.

This program is built on evidence suggesting that specific dietary strategies can modulate immune function and reduce oxidative stress. The plan prioritizes polyphenols and fiber to manage C-reactive protein levels, prebiotics to restore the gut barrier, and essential fats to support hormone regulation and liver health. To help you implement these science-backed principles, we have curated a list of key dietary focus areas:

Consume Anti-Inflammatory Vegetables: Incorporate spinach and olives to provide polyphenols that help control oxidative stress and modulate the inflammatory response.
Support Gut Health: Eat asparagus, garlic, and leafy greens to provide prebiotic fiber that feeds beneficial bacteria and restores the gut barrier.
Boost Liver Function: Include cruciferous vegetables like broccoli, cauliflower, and kale, which contain indoles (like indole-3-Carbinol) essential for liver detoxification and hormone balance.
Prioritize Omega-3 Fats: Obtain healthy fats from salmon, mackerel, and sardines to assist with cortisol regulation and reduce inflammation.
Enhance Immune Defense: Ensure adequate intake of zinc and selenium from meats and poultry, and Vitamin A and C from nutrient-dense produce like lemon, kale, and spinach to support antioxidant status.

To start following this plan, click the button below to access your personalized PlexusDx meal planning tool. If you need to adjust any meals to better fit your preferences or inventory, you can easily find alternatives that adhere to the autoimmune and ketogenic rules using our "Swap" feature. Follow these simple steps to customize your menu:

Locate the meal you wish to change on your daily planner.
Click the three dots next to the meal name.
Select "Swap recipe" from the menu options.
Choose "Swap" to change a single meal or "Swap all" to replace that recipe for the entire week.
Keep clicking "Swap" to browse through alternatives that match your specific plan rules, such as gluten-free, dairy-free, and egg-free options.

PlexusDx provides educational information about genetic predispositions only. This content is not medical advice. Always discuss genetic findings, test results, symptoms, and treatment decisions with your healthcare provider or an allergist to determine appropriate care for your situation.

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Diets & Meal Plans