Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx: Understanding the Importance of eGFR in Kidney Health

PlexusDx stands as a top health report provider by delivering important information about genetic factors which influence your general health. We explore the important field of eGFR which functions as a key biomarker to assess kidney performance and its longer-term health effects. The estimated glomerular filtration rate (eGFR) functions as a critical measure to determine kidney performance efficiency. The calculation of this metric involves multiple influences including sex, age, ethnicity, and blood creatinine levels. Creatinine functions as a critical element in this assessment because it represents a waste product normally removed by the kidneys. The reduction in kidney function results in elevated blood creatinine levels which indicate possible health concerns. Keeping eGFR levels within the normal range ensures your kidneys function optimally. Your kidneys perform effective blood filtration without becoming overworked. Reduced kidney efficiency becomes evident through a low eGFR which can result from either chronic kidney disease or acute kidney injury. Numerous risk factors such as high blood pressure and diabetes contribute to kidney disease while factors like obesity and smoking also play a role along with genetic predispositions and conditions like premature birth. Genetic factors determine up to 45% of eGFR level variations as they play a significant role in its determination. Knowledge of your genetic risk for reduced eGFR levels allows you to implement early measures to protect your kidney health. Regular monitoring of eGFR levels combined with kidney-protective lifestyle choices will help reduce risks related to reduced kidney function. PlexusDx presents Precision Health & Wellness tests which analyze genetic traits that influence bodily functioning and lifespan for people interested in their eGFR and kidney health. The Precision Health & Wellness tests available on PlexusDx.com and Amazon and Walmart help people understand their genetic predispositions to make better health choices. eGFR serves as an essential indicator of kidney function which reveals important information about long-term health prospects. PlexusDx's Precision Health & Wellness tests deliver valuable insights that help individuals take control of their kidney health while making well-informed decisions to improve their general health status. Begin your health journey today by taking advantage of the powerful genetic testing solutions PlexusDx has to offer.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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