TrimRx advertises tirzepatide at $349/month, but checkout-verified pricing shows $399 month-to-month and prepaid plans from $1,068 for three months to $3,518 for twelve. We compare billing structure, dose pricing, and total cost over twelve months.

TrimRx vs Ro vs PlexusDx in 2026: real annual cost math, compounded vs FDA-approved branded medication, oral pill options, safety oversight, and PlexusDx's optional genetic-baseline test. Includes a four-question decision frame and pricing across PlexusDx Microdose GLP-1, Semaglutide Injection, Tirzepatide Injection, and GLP-Squared.

MEDVi, TrimRx, and PlexusDx all offer compounded GLP-1 programs, but only two publish a price you can check. This three-way comparison lines up same-medication pricing, introductory versus recurring charges, dose policies, included support, and cancellation terms as read September 22, 2026, and says plainly where the figures are unknown.

Pennsylvania Medicaid cut GLP-1 coverage for adult weight loss on January 1, 2026. This guide walks the legal cash-pay telehealth options that ship to PA, the compounded vs FDA-approved branded distinction, real annualized costs, and where PlexusDx Microdose GLP-1 ($129/mo), Semaglutide Injection ($189/mo), and Tirzepatide Injection ($289/mo) sit relative to Eden, Ro, TrimRx, Willow, and MEDVi — with the optional Precision Peptide Genetic Test adding pathway-level genetic context before week one.

Compounded tirzepatide provider rankings cycle through MEDVi, Eden, Yucca Health, Willow, and TrimRx. PlexusDx Tirzepatide Injection ($289/mo) and Tirzepatide Oral ($349/mo) compare on price, oversight, and genetic-test personalization.