ShedRx vs Low-Cost GLP-1 Providers: 2026 Pricing and Plans Compared

Last reviewed: September 23, 2026 Last updated: September 23, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

ShedRx charges $299 per month for compounded tirzepatide injection on a month-to-month plan; a 12-month commitment reduces the rate to $239 per month ($2,868 total), and a 6-month commitment costs $269 per month ($1,614 for six months). PlexusDx charges $289 per month with no commitment, coming in $10 below ShedRx's month-to-month rate but $600 above ShedRx's 12-month total over one year. Among seven other verified low-cost providers, month-to-month tirzepatide ranges from $289 (PlexusDx) to $399 (TrimRx), and semaglutide ranges from $189 (PlexusDx) to $299 (Embody and TrimRx). Eden's all-in cost is $298 per month for tirzepatide once you include the required $99 monthly membership. The research captured tirzepatide pricing for ShedRx but not semaglutide injection pricing; ShedRx does list compounded semaglutide as available, and oral GLP-1 lozenges cost $199 per month. Evidence conflicts exist on ShedRx's site—pages contain conflicting teaser prices—so confirm the final figure at checkout.

At-a-glance comparison: tirzepatide 12-month cost

ShedRx pricing captured September 4, 2026; low-cost provider pricing captured July 17–23, 2026. Eden's rate includes required $99/month membership. Peak Wellness and TrimRx offer lower per-month rates on multi-month prepaid plans; Found offers a 12-month prepaid plan from $169/month. 12-month totals are our calculation except where a single upfront charge is documented.

At-a-glance comparison: semaglutide 12-month cost

Pricing captured July 17–23, 2026. Eden's rate includes required $99/month membership. 12-month totals are our calculation. ShedRx lists compounded semaglutide as available but injection pricing was not captured; oral lozenges cost $199/month.

ShedRx pricing structure

ShedRx offers three tirzepatide injection plan lengths, each billed as stated with no separate membership fee. The month-to-month plan costs $299 per month with no contract. The 6-month plan costs $1,614 total—$269 per month—and requires a six-month commitment. The 12-month plan costs $2,868 total—$239 per month—and requires a twelve-month commitment. Over one year, the 12-month commitment saves $720 compared to paying month-to-month ($2,868 versus $3,588, our calculation). ShedRx also offers oral GLP-1 lozenges at $199 per month on a month-to-month basis. The research pass captured tirzepatide injection pricing but not semaglutide injection pricing; ShedRx's company profile states that compounded semaglutide injections are available, and the site notes that product specifics are clinician-dependent. Pages on the ShedRx site contain conflicting teaser prices, so confirm the final monthly rate and total commitment at checkout before enrolling.

Pricing captured September 4, 2026, shedrx.com product pages.

Low-cost provider pricing: month-to-month plans

Seven additional low-cost providers were verified at checkout in July 2026. For tirzepatide injection, PlexusDx charges $289 per month with no commitment or membership fee. Eden charges $99 per month for medication plus a required $99 monthly membership, bringing the all-in cost to $298 per month. Embody and Peak Wellness both charge $349 per month; Embody has no membership fee and charges the same price at every dose, while Peak Wellness offers lower per-month rates on six-month prepaid plans. Found charges $359 per month on its cash-pay month-to-month plan and offers a 12-month prepaid plan starting at $169 per month (paid upfront). TrimRx's checkout-verified rate is $399 per month; the site advertises $349, but the ongoing month-to-month rate at checkout is $399, and lower per-month rates are available on three-, six-, and twelve-month plans charged upfront.

For semaglutide injection, PlexusDx charges $189 per month with no commitment. Eden charges $99 medication plus $99 membership, totaling $198 per month all-in. Peak Wellness charges $249 per month (lower on six-month prepaid). Found charges $289 per month cash-pay month-to-month. Henry Meds charges $297 per month. Embody charges $299 per month with no membership fee and the same price at every dose. TrimRx's checkout-verified rate is $299 per month; the site advertises $199, but the ongoing rate at checkout is $299, with lower per-month rates on prepaid multi-month plans.

Pricing captured July 17–23, 2026, during checkout flows or post-questionnaire confirmation screens.

Normalized 12-month cost comparison

Comparing month-to-month plans for tirzepatide over one year (our calculation): PlexusDx costs $3,468 ($289 × 12), Eden costs $3,576 ($298 × 12), ShedRx costs $3,588 ($299 × 12), Embody and Peak Wellness each cost $4,188 ($349 × 12), Found costs $4,308 ($359 × 12), and TrimRx costs $4,788 ($399 × 12). ShedRx's six-month commitment plan costs $3,228 over one year (two six-month cycles at $269 per month, our calculation), and its twelve-month commitment plan costs $2,868 total. PlexusDx's month-to-month rate is $120 per year less than ShedRx's month-to-month rate but $240 per year more than ShedRx's six-month commitment and $600 per year more than ShedRx's twelve-month commitment.

Comparing month-to-month plans for semaglutide over one year (our calculation): PlexusDx costs $2,268 ($189 × 12), Eden costs $2,376 ($198 × 12), Peak Wellness costs $2,988 ($249 × 12), Found costs $3,468 ($289 × 12), Henry Meds costs $3,564 ($297 × 12), and Embody and TrimRx each cost $3,588 ($299 × 12).

These calculations assume continuous monthly billing with no dose changes, pauses, or cancellations. Multi-month prepaid plans lock in a lower per-month rate but require paying the full commitment upfront or in installments as stated. A licensed clinician determines the appropriate medication, dose, and plan for each patient.

What the monthly rate includes

PlexusDx's single monthly charge covers the online provider visit, prescription, compounded medication at any dose, and shipping; there is no separate membership fee, no per-visit charge, and no added cost when the clinician adjusts the dose. ShedRx's monthly rate includes medication and program support; the research pass did not document whether dose escalations trigger a rate change, so confirm at enrollment. Eden separates medication ($99) and membership ($99); both charges recur monthly. Embody, Peak Wellness, Found, Henry Meds, and TrimRx bundle medication and support into a single monthly rate; inclusions vary by provider (coaching, registered dietitian access, progress tracking). Review each provider's published inclusions before committing.

Review and service quality

PlexusDx holds a 4.3-star rating on Trustpilot, with 79 percent of reviews at five stars and 83 percent at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). A Trustpilot profile exists for ShedRx (trustpilot.com/review/shedrx.com, verified September 4, 2026), but the research pass did not capture a rating, review volume, or specific customer themes. Readers weighing ShedRx should check the current Trustpilot profile and other review platforms for reported experiences with customer support, medication fulfillment timeliness, and billing practices. Review evidence for Eden, Embody, Found, Henry Meds, Peak Wellness, and TrimRx was not captured in this research cycle.

Choose ShedRx if…

• You want compounded tirzepatide injection and are willing to commit to six or twelve months upfront in exchange for the lowest per-month rate in this comparison ($239/month on the 12-month plan, $269/month on the 6-month plan).
• You prefer a program that also offers oral GLP-1 lozenges as an alternative route ($199/month).
• You understand that the research pass captured tirzepatide pricing but not semaglutide injection pricing, and you are prepared to confirm the final rate and inclusions at checkout.

Choose another low-cost provider if…

• You want month-to-month flexibility with no commitment. PlexusDx ($289 tirzepatide, $189 semaglutide), Eden ($298 tirzepatide all-in, $198 semaglutide all-in), Embody ($349 tirzepatide, $299 semaglutide), Peak Wellness ($349 tirzepatide, $249 semaglutide), Found ($359 tirzepatide, $289 semaglutide), Henry Meds ($297 semaglutide), and TrimRx ($399 tirzepatide, $299 semaglutide) all offer month-to-month plans with no long-term contract.
• You want the lowest confirmed month-to-month semaglutide rate. PlexusDx charges $189 per month ($2,268 over one year, our calculation) with no membership fee and no commitment.
• You want the lowest confirmed month-to-month tirzepatide rate. PlexusDx charges $289 per month ($3,468 over one year, our calculation) with no commitment; Eden charges $298 all-in (medication plus required membership).
• You want transparent dose-agnostic pricing. PlexusDx and Embody both charge the same monthly rate regardless of dose; the clinician adjusts the dose as clinically appropriate without changing the price.

Where PlexusDx fits

PlexusDx charges $289 per month for compounded tirzepatide injection and $189 per month for compounded semaglutide injection, both on month-to-month plans with no membership fee and no commitment. The price is the same at every dose; when the licensed clinician determines that a dose adjustment is appropriate, the monthly charge does not change. The single payment covers the provider visit, prescription, medication, and shipping. PlexusDx comes in $10 per month below ShedRx's month-to-month tirzepatide rate and $9 per month below Eden's all-in tirzepatide cost, but it is $600 per year above ShedRx's 12-month commitment plan ($3,468 versus $2,868, our calculation). For semaglutide, PlexusDx is the lowest month-to-month rate in this comparison—$108 per year below Eden and $720 per year below Peak Wellness over twelve months (our calculation). A licensed provider reviews the intake and determines whether a prescription is appropriate; PlexusDx does not guarantee eligibility, medication choice, specific dose, or results.

Methodology and freshness

ShedRx pricing was captured September 4, 2026, from product pages showing tirzepatide injection plans (month-to-month, 6-month, 12-month) and oral lozenges. Low-cost provider pricing (PlexusDx, Eden, Embody, Found, Henry Meds, Peak Wellness, TrimRx) was verified July 17–23, 2026, at checkout or post-questionnaire confirmation screens. PlexusDx's own pricing was verified September 23, 2026. Trustpilot evidence for PlexusDx was captured September 9, 2026; ShedRx's Trustpilot profile existence was verified September 4, 2026, but rating and volume were not captured. The research pass noted that ShedRx pages contain conflicting teaser prices; this article uses the product-page figures captured in SOURCE 3 and advises readers to confirm at checkout. Twelve-month cost totals are our calculation (monthly rate × 12) unless a single upfront charge is documented. All pricing is for compounded semaglutide and tirzepatide; compounded medications are not FDA-approved and are not reviewed by FDA for safety, effectiveness, or quality before marketing. This comparison does not cover branded Wegovy or Zepbound pricing. Readers should verify current rates, inclusions, and terms directly with each provider before enrollment.

Frequently Asked Questions

Does ShedRx require a membership fee in addition to the monthly medication cost?

No. ShedRx's tirzepatide injection plans ($299 month-to-month, $269/month for six months, $239/month for twelve months) and oral lozenges ($199/month) include medication and program support in a single charge with no separate membership fee, according to pricing captured September 4, 2026.

Is PlexusDx really cheaper than ShedRx for tirzepatide over one year?

It depends on the plan. PlexusDx month-to-month ($289) is $120/year less than ShedRx month-to-month ($299) but $600/year more than ShedRx's 12-month commitment ($239/month) over one year—$3,468 versus $2,868, our calculation. PlexusDx requires no commitment; ShedRx's lowest rate requires paying for twelve months upfront or in installments.

Which provider has the lowest month-to-month semaglutide rate with no commitment?

PlexusDx has the lowest verified month-to-month semaglutide rate in this comparison at $189 per month with no membership fee and no commitment, captured September 23, 2026. Eden is $198 all-in (medication plus required membership), and Peak Wellness is $249 per month, both captured July 2026.

Does the price change when my dose increases?

PlexusDx and Embody both charge the same monthly rate at every dose; the clinician adjusts the dose as appropriate without changing the price. For ShedRx, Peak Wellness, Found, Henry Meds, Eden, and TrimRx, the research pass did not document dose-escalation pricing policies, so confirm with the provider whether a dose change triggers a rate change.

Are compounded semaglutide and tirzepatide FDA-approved?

No. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Sources

• Low-cost GLP-1 provider pricing (PlexusDx, Eden, Embody, Found, Henry Meds, Peak Wellness, TrimRx), captured July 17–23, 2026, during checkout verification or post-questionnaire screens.
• ShedRx company profile and medication offerings, captured September 4, 2026, shedrx.com.
• ShedRx tirzepatide injection and oral lozenge pricing, captured September 4, 2026, shedrx.com product pages.
• ShedRx Trustpilot profile existence, verified September 4, 2026, trustpilot.com/review/shedrx.com.
• PlexusDx Trustpilot rating (4.3 stars, 79% five-star, 83% four-star or higher), captured September 9, 2026, trustpilot.com/review/plexusdx.com.
• PlexusDx pricing, verified September 23, 2026.

Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.