Last reviewed: September 17, 2026
Last updated: September 17, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
A program advertising "$149/month semaglutide" may actually cost $248/month once you add a mandatory membership, or $299/month after an introductory period ends, or vary by dose. The most economical path depends on whether you value predictable flat pricing, tolerance for upfront payment, or willingness to navigate per-dose models. All-inclusive programs—medication, provider access, and shipping in one figure—deliver the clearest recurring cost; membership-plus-medication structures require you to sum two line items every month; and per-dose models mean your cost rises as your dose increases. Among the programs captured in this analysis, PlexusDx semaglutide injection ($189 month-to-month, $169 three-month prepaid, $149 six-month prepaid), OrderlyMeds ($149/month ongoing after a two-month starter), and Eden ($99 medication + $99 membership = $198 total) sit near the middle of the all-inclusive pack, while Mochi Health's per-dose structure starts at $60 medication plus membership but climbs with titration, and MEDVi charges an introductory first-month rate of $179 then $299 for semaglutide refills.
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At-a-glance comparison: ongoing monthly cost, semaglutide injection
| Program |
Month-to-Month |
Prepaid Plans |
Membership |
Notes |
| OrderlyMeds |
$149 |
Two-month starter $149 total |
None |
All-inclusive; flat dose pricing |
| PlexusDx |
$189 |
$169 (3-mo), $149 (6-mo) |
None |
All-inclusive; flat dose pricing |
| Eden |
$198 total |
— |
$99 ($39 first month) |
$99 medication + $99 membership |
| Hims & Hers |
— |
$199 (6-mo prepaid, $1,194 upfront) |
None advertised |
Six-month commitment required |
| TrimRx |
$299 |
Lower on 3-, 6-, 12-mo |
None |
Checkout ongoing $299 vs $199 advertised |
| Peak Wellness |
$249 |
Lower on 6-mo |
None |
All-inclusive |
| Fridays Health |
$249 |
$117 effective (multi-mo prepay) |
None |
Promo landing differs from product page |
| Found |
$289 |
$169 (annual, $2,028 upfront) |
Included |
Care program + medication; insurance path $199 + copay |
| MEDVi |
$299 refill |
— |
None |
$179 first month, then $299 ongoing |
| Henry Meds |
$297 |
$197 paid-in-full (12-mo, $2,364 upfront) |
None |
All-inclusive; oral routes $179–$249 |
| Embody |
$299 |
— |
None |
Flat dose pricing |
| Remedy Meds |
$299.70 |
— |
None advertised |
Advertised as $9.99/day |
| Mochi Health |
Starting dose $60 medication |
— |
$39 first month; ongoing TBD |
Per-dose pricing; higher doses vary |
| Zealthy |
— |
From $151 (quarterly) |
Intake required |
Branded options as low as $25 with insurance |
Data captured July 17–September 4, 2026. Month-to-month figures reflect standard ongoing rates unless noted. Prepaid figures are per-month equivalents when paid upfront (our calculation). OrderlyMeds starter is a two-month supply billed once. Confirm current pricing at checkout.
Breaking down the line items
Telehealth GLP-1 costs arrive in up to five pieces: medication, provider visit or membership, laboratory work, shipping, and upfront commitment penalties. Programs that bundle all five into one monthly figure deliver the simplest budgeting; programs that separate medication from membership require you to track two charges; and per-dose models mean your monthly bill rises alongside your clinical progress.
Medication cost: per-dose, flat-rate, or hybrid
Mochi Health charges per dose—$60/month for starting-dose semaglutide, climbing as your provider titrates upward—so your year-one cost is a moving target. OrderlyMeds, PlexusDx, Embody, and Peak Wellness hold the medication price constant regardless of dose, which means you pay the same amount at 0.25 mg as you do at 2.4 mg. MEDVi operates a hybrid model: a lower introductory first-month rate of $179 for semaglutide injection, then $299 every refill thereafter, with no additional charge when dose increases.
Membership fees
Eden collects $99/month membership on top of $99/month medication ($198 total ongoing; first month $138 total because membership is introductory $39 first month, then $99 ongoing). Found includes its care program in the advertised cash-pay rate ($289/month semaglutide, $359/month tirzepatide), though its insurance-support tier adds a separate $199/month subscription plus your plan's copay. PlexusDx, OrderlyMeds, Embody, Henry Meds, Peak Wellness, TrimRx, MEDVi, Fridays Health, and Remedy Meds advertise no separate membership line item; every service component is bundled into the medication price. Zealthy's membership structure requires intake to confirm.
Laboratory work and provider visits
None of the fourteen programs captured in this analysis itemize a separate laboratory or provider-visit fee in their standard monthly flow; all represent their ongoing charge as covering clinical oversight, prescription renewal, and asynchronous or scheduled check-ins. If your state or clinical profile requires additional labs, confirm whether those trigger an extra charge or remain covered under the published rate.
Shipping
Every program reviewed includes shipping in its advertised price. Ground delivery is standard; most ship medication in temperature-controlled packaging at no additional cost.
Twelve-month total cost: like-for-like comparison
The advertised per-month figure rarely tells the full story. Multi-month prepayment unlocks lower effective rates but requires upfront capital; introductory pricing expires; and per-dose models compound over time. The table below calculates the true twelve-month outlay for semaglutide injection under each program's standard path, assuming continuous enrollment and typical titration where applicable.
| Program |
Payment Model |
12-Month Total (our calculation) |
Effective Monthly |
| OrderlyMeds |
Two-month starter $149, then $149/mo × 10 |
$1,639 |
$136.58 |
| Fridays Health |
Multi-month prepay advertised lowest |
~$1,404 |
$117 (advertised prepay rate) |
| PlexusDx |
6-month prepaid × 2 |
$1,788 |
$149 |
| Zealthy |
Quarterly prepaid |
~$1,812 |
$151 (advertised quarterly rate) |
| Found |
Annual prepaid |
$2,028 |
$169 |
| PlexusDx |
3-month prepaid × 4 |
$2,028 |
$169 |
| PlexusDx |
Month-to-month × 12 |
$2,268 |
$189 |
| Henry Meds |
12-month paid-in-full |
$2,364 |
$197 |
| Eden |
$99 med + $99 membership (first mo introductory $138 total) |
$2,277 |
$189.75 |
| Hims & Hers |
6-month prepaid × 2 |
$2,388 |
$199 |
| Peak Wellness |
Month-to-month × 12 |
$2,988 |
$249 |
| Found |
Month-to-month × 12 |
$3,468 |
$289 |
| TrimRx |
Month-to-month × 12 |
$3,588 |
$299 |
| Embody |
Month-to-month × 12 |
$3,588 |
$299 |
| MEDVi |
$179 first month + $299/mo × 11 |
$3,468 |
$289 average |
| Henry Meds |
Month-to-month × 12 |
$3,564 |
$297 |
| Remedy Meds |
Month-to-month × 12 |
$3,596 |
$299.70 |
All twelve-month totals are our calculation based on the best available evidence captured July 17–September 4, 2026. Mochi Health per-dose totals require individual titration history and are excluded. Zealthy and Fridays Health prepay totals use advertised effective rates; confirm exact terms at intake. OrderlyMeds total reflects one two-month starter charge ($149) plus ten additional months at $149 each.
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Decision factors beyond price
The lowest twelve-month total does not automatically make a program the best fit. Service quality, review record, formulary breadth, and refund or transfer policy matter as much as cost when you're committing to a year-long therapeutic intervention.
Service quality and review evidence
Mochi Health holds a 4.5-star Trustpilot rating across approximately 18,000 reviews, though one captured review reported a provider appearing late and not engaging during the visit (Trustpilot, captured September 4, 2026). Eden also holds a 4.5-star rating across roughly 5,000 reviews; one captured 1-star review described an 11-day order delay and repeated requests for records the company had previously issued (Trustpilot, captured September 4, 2026). Henry Meds shows a 4.4-star rating across approximately 13,000 reviews (Trustpilot, captured September 4, 2026). MEDVi and PlexusDx both hold 4.3-star ratings—MEDVi across approximately 15,000 reviews, PlexusDx across 79 percent five-star reviews and 83 percent four-star or higher (Trustpilot, captured September 9, 2026; trustpilot.com/review/plexusdx.com). Fridays Health sits at 4.2 stars across roughly 4,700 reviews (Trustpilot, captured September 4, 2026). Found shows a 4.1-star rating across approximately 732 reviews (Trustpilot, captured September 4, 2026). OrderlyMeds holds a 3.6-star rating across approximately 634 reviews; captured 1-star and 2-star reports cite fast charging but slow refunds, non-response, delayed shipping, pharmacy changes, and unwanted calls or texts after opt-out (Trustpilot, captured September 4, 2026).
Route and formulary options
Henry Meds offers semaglutide injection, sublingual tablets, and premium oral formulations, plus oral tirzepatide dissolving tablets but not tirzepatide injection (captured September 4, 2026). PlexusDx, Eden, Fridays Health, and Mochi Health each provide both compounded semaglutide and tirzepatide injections; PlexusDx also offers oral capsule formulations of both compounds. Hims & Hers, Zealthy, and Found offer pathways to branded Wegovy, Ozempic, Zepbound, or Mounjaro alongside compounded options. If you require or prefer a specific route—injection, sublingual, oral capsule—confirm formulary availability before committing to a prepaid plan.
Refund and transfer policies
Multi-month prepayment locks in a lower effective rate but removes flexibility if you experience intolerable side effects, achieve your goal early, or wish to switch providers. OrderlyMeds advertises month-to-month terms with no contract, but captured review reports describe slow refunds and non-response (Trustpilot, captured September 4, 2026). Found, Henry Meds, and Hims & Hers each require substantial upfront payment for their lowest advertised rates; confirm whether unused months are refundable or transferable if you discontinue early. PlexusDx month-to-month and three-month plans permit cancellation without forfeiting future months; six-month prepaid plans should be confirmed for refund terms at checkout.
Choose OrderlyMeds if…
You want the lowest twelve-month all-inclusive total captured in this analysis ($1,639 for semaglutide injection, our calculation) and accept a 3.6-star Trustpilot rating with review reports of delayed refunds and shipping inconsistencies. OrderlyMeds delivers flat-rate dosing—$149/month ongoing after a two-month starter—with no membership fee, no dose-tier increases, and medication, provider access, and shipping bundled. Verify multi-month transfer plan availability in your state before enrollment (data captured September 4, 2026).
Choose Fridays Health if…
You can commit to a multi-month prepaid plan and want an advertised effective rate as low as $117/month for semaglutide or $190/month for tirzepatide. Fridays Health holds a 4.2-star Trustpilot rating across approximately 4,700 reviews. Note that promotional landing-page prices differ from product-page standard prices; confirm the exact prepayment term and total at checkout (data captured September 4, 2026).
Choose Found if…
You value an integrated behavioral-health program—coaching, nutrition guidance, and clinical oversight in one subscription—and can pay $2,028 upfront for twelve months of semaglutide ($169/month effective, our calculation) or accept $289/month month-to-month. Found also offers an insurance-support path at $199/month plus your plan's copay. Found holds a 4.1-star Trustpilot rating across approximately 732 reviews (captured September 4, 2026).
Choose Henry Meds if…
You want access to multiple semaglutide routes—injection at $297/month, sublingual tablets at $249/month, or premium oral formulations at $179/month—under one provider, and you can pay $2,364 upfront for a twelve-month injection plan ($197/month effective, our calculation) or accept month-to-month rates. Henry Meds holds a 4.4-star Trustpilot rating across approximately 13,000 reviews. Note that tirzepatide is available only as an oral dissolving tablet, not injection (data captured September 4, 2026).
Choose Mochi Health if…
You prefer to pay only for your current dose—starting at $60/month semaglutide medication or $90/month tirzepatide medication—and accept that your monthly cost will rise as your provider titrates upward. Add $39 first-month membership; ongoing membership amount requires confirmation. Mochi Health holds a 4.5-star Trustpilot rating across approximately 18,000 reviews, though one captured report described a provider appearing late and not engaging (captured September 4, 2026).
Choose Eden if…
You want $99/month medication with unlimited provider messaging and are comfortable with a mandatory $99/month membership ($198 total ongoing; $138 first month). Eden holds a 4.5-star Trustpilot rating across approximately 5,000 reviews, though one captured 1-star review reported an 11-day order delay and repeated record requests (captured September 4, 2026).
Choose Hims & Hers if…
You can commit to a six-month prepaid plan at $199/month effective ($1,194 upfront, our calculation; $2,388 for twelve months across two six-month cycles) and want the brand recognition and scale of a publicly traded telehealth platform. Hims & Hers offers pathways to branded Wegovy, Ozempic, Zepbound, and Mounjaro alongside compounded semaglutide. Confirm eligibility and dose-dependent offer details at intake (data captured September 4, 2026).
Where PlexusDx fits
PlexusDx semaglutide injection sits at $189 month-to-month, $169 per month on a three-month prepaid plan, and $149 per month on a six-month prepaid plan—no membership fee, no dose tiers, and medication, provider review, unlimited asynchronous support, and shipping included. The six-month rate matches OrderlyMeds' ongoing rate and undercuts Henry Meds month-to-month by $148/month, Eden's total recurring cost by $49/month, and MEDVi's refill rate by $150/month. Over twelve months, PlexusDx six-month plans ($1,788 total, our calculation) cost $149 more than OrderlyMeds ($1,639), $240 less than Found annual prepay ($2,028), and $1,680 less than MEDVi month-to-month ($3,468). PlexusDx holds a 4.3-star Trustpilot rating, with 79 percent of reviews at five stars and 83 percent at four stars or higher (captured September 9, 2026; trustpilot.com/review/plexusdx.com). If you want predictable flat-rate pricing, modest prepayment commitment, and a provider who will not raise your cost when your dose increases, PlexusDx delivers a straightforward middle path between the lowest floor and the highest-touch concierge models.
Methodology and freshness
We captured advertised pricing, membership structures, and prepayment terms from each program's public website, FAQ pages, and checkout flows between July 17 and September 4, 2026. Where a program displayed conflicting figures across landing pages and product pages, we note the conflict and advise confirming at checkout. Trustpilot ratings and review themes were captured on September 4, 2026; individual review reports are described as anecdotes, not established patterns. Twelve-month totals and effective monthly rates are our calculation based on the best available evidence; they assume continuous enrollment, no dose-dependent surcharges where flat pricing is advertised, and standard titration where per-dose models apply. Mochi Health per-dose totals depend on individual titration history and are excluded from twelve-month comparisons. We applied the same evidence standard to PlexusDx and to every competing program.
Frequently Asked Questions
Do GLP-1 telehealth programs charge separately for labs or provider visits?
None of the fourteen programs reviewed itemize a separate laboratory or provider-visit fee in their standard monthly flow. All represent their ongoing charge as covering clinical oversight, prescription renewal, and asynchronous or scheduled check-ins. If your state or clinical profile requires additional labs, confirm whether those trigger an extra charge.
What is the true difference between a program that advertises "$149/month" and one that advertises "$149 medication plus $99 membership"?
The first is $149 total; the second is $248 total every month. Programs that separate medication from membership require you to budget for two recurring charges. All-inclusive programs bundle every service component into one figure, which simplifies budgeting but may carry a higher headline number.
Does my monthly cost increase when my semaglutide or tirzepatide dose increases?
It depends on the program's pricing model. PlexusDx, OrderlyMeds, Embody, Peak Wellness, and MEDVi hold the price constant regardless of dose. Mochi Health charges per dose, so your monthly cost climbs as your provider titrates upward. Confirm dose-pricing policy before enrollment if you anticipate reaching a maintenance dose above the starting level.
Are multi-month prepaid plans refundable if I discontinue early?
Refund and transfer policies vary by program and are not uniformly disclosed. Found, Henry Meds, and Hims & Hers each require substantial upfront payment for their lowest advertised rates; confirm whether unused months are refundable or transferable if you discontinue early. Month-to-month plans eliminate this risk but carry higher per-month costs.
Which programs offer both semaglutide and tirzepatide injections, and which offer oral or sublingual routes?
PlexusDx, Eden, Fridays Health, and Mochi Health each provide both compounded semaglutide and tirzepatide injections; PlexusDx also offers oral capsule formulations of both compounds. Henry Meds offers semaglutide injection, sublingual tablets, and premium oral formulations, plus oral tirzepatide dissolving tablets but not tirzepatide injection. Confirm formulary availability at intake if you require a specific route.
Sources
- Source 1: Internal PlexusDx pricing database and competitor checkout verification, captured July 17–23, 2026
- Source 2: Competitor program websites, FAQ pages, and pricing pages, captured September 4, 2026
- Source 3: Competitor checkout flows and intake gates, captured September 4, 2026
- Source 4: Trustpilot.com review aggregation for Eden, Found, Henry Meds, MEDVi, OrderlyMeds, Fridays Health, Mochi Health, and Hims & Hers, captured September 4, 2026
- Source 5: Competitor landing-page and product-page verification for MEDVi, Zealthy, and Remedy Meds, captured September 4, 2026
- PlexusDx Trustpilot profile: trustpilot.com/review/plexusdx.com, captured September 9, 2026
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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. PlexusDx works with licensed 503A compounding pharmacies. A licensed clinician determines whether a prescription is appropriate for an individual patient.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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