Last reviewed: September 13, 2026
Last updated: September 13, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
Pomegranate Health's product page lists compounded semaglutide injection at $119 per month with monthly billing and no membership fee, and compounded tirzepatide with B6 at $149 per month, both captured September 4, 2026. Those rates are lower than PlexusDx's month-to-month semaglutide ($189) and tirzepatide ($289) but higher than PlexusDx's 6-month prepaid rate of $149 per month for semaglutide and $249 per month for tirzepatide. Historical materials mention a consult deposit; the current product page states no extra fee—confirm the final fee structure at checkout. Evidence documents starter pricing; dose escalation tiers exist in the app but pricing beyond the entry level was not captured. Over 12 months on the documented monthly rate, Pomegranate Health semaglutide totals $1,428 versus PlexusDx month-to-month at $2,268 or PlexusDx 6-month prepaid at $1,788 (our calculation, prepaid). The Pomegranate Health advantage holds if the $119 rate remains unchanged across dose increases and no hidden fees emerge.
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At-a-glance comparison: Pomegranate Health vs PlexusDx semaglutide
| Item |
Pomegranate Health |
PlexusDx (MTM) |
PlexusDx (6-mo prepaid) |
| Semaglutide injection (monthly) |
$119 |
$189 |
$149/mo (prepaid) |
| Membership / service fee |
$0 (product page claim; confirm at checkout) |
$0 |
$0 |
| 12-month total |
$1,428 (our calculation) |
$2,268 (our calculation) |
$1,788 (our calculation) |
| Commitment |
Monthly billing |
Month-to-month |
6-month prepay |
| Dose-tier pricing |
Available in app (not documented) |
Flat rate all doses |
Flat rate all doses |
| Evidence captured |
2026-09-04 |
2026-07-17–23 |
2026-07-17–23 |
All figures from primary sources. Pomegranate Health pricing from product page and app pricing page. PlexusDx 6-month figure is a prepaid per-month equivalent (our calculation). 12-month totals are our calculation.
Pomegranate Health semaglutide pricing breakdown
Pomegranate Health's product page for compounded semaglutide injection states a monthly rate of $119 with monthly billing and no membership or extra fee, captured September 4, 2026 from joinpomegranate.com/products/compounded-semaglutide and the app pricing page at app.joinpomegranate.com/pricing. The same sources list compounded tirzepatide with B6 at $149 per month. Both figures match the checkout/upfront cost documented in the evidence; there is no prepay requirement and no separate introductory versus refill rate.
Historical materials reference a consult deposit, but the current product page explicitly claims no membership or extra fee. This discrepancy was flagged in the research as "Primary-conflict" requiring checkout confirmation. Until that conflict is resolved, readers should confirm the complete fee structure—including any consultation, onboarding, or visit charges—during signup.
The documented $119 semaglutide rate is a starter price. The evidence notes that dose tiers are available in the Pomegranate Health app, but pricing for higher doses was not captured. If monthly costs increase as dose escalates, the 12-month total will exceed the $1,428 figure calculated from the $119 entry rate. Readers planning long-term treatment should ask about the full dose ladder and whether the per-month price changes at 0.5 mg, 1.0 mg, 1.7 mg, or 2.4 mg weekly doses.
PlexusDx semaglutide pricing: month-to-month and prepaid options
PlexusDx charges $189 per month for compounded semaglutide injection on a month-to-month basis, with no membership fee and the same flat rate at every dose from 0.25 mg through 2.4 mg weekly. That rate holds whether you are on starter, titration, or maintenance dosing. Multi-month prepaid plans lower the effective monthly cost: $169 per month on a 3-month plan ($507 upfront) or $149 per month on a 6-month plan ($894 upfront), both captured July 17–23, 2026 from plexusdx.com product pages.
Over 12 months, PlexusDx month-to-month semaglutide totals $2,268 (our calculation: $189 × 12). The 6-month prepaid plan requires two cycles over the year, totaling $1,788 (our calculation: $894 × 2, or $149 × 12). The 3-month plan over 12 months totals $2,028 (our calculation: $507 × 4, or $169 × 12). All PlexusDx prices are all-inclusive: provider visit, prescription, medication, and shipping with no separate consultation or membership charge.
Like-for-like 12-month cost comparison
Comparing monthly-billed plans (Pomegranate Health monthly versus PlexusDx month-to-month), Pomegranate Health semaglutide costs $1,428 over 12 months and PlexusDx costs $2,268, a difference of $840 in Pomegranate Health's favor (our calculation). Pomegranate Health's $119 rate is $70 per month lower than PlexusDx's $189 month-to-month rate.
Comparing Pomegranate Health's monthly plan to PlexusDx's 6-month prepaid plan, Pomegranate Health totals $1,428 and PlexusDx totals $1,788, a difference of $360 over the year (our calculation). Pomegranate Health's $119 monthly rate is $30 per month lower than PlexusDx's $149 prepaid rate, but PlexusDx requires $894 upfront every six months while Pomegranate Health bills $119 each month with no prepayment.
For tirzepatide, Pomegranate Health lists $149 per month ($1,788 over 12 months, our calculation) versus PlexusDx month-to-month at $289 per month ($3,468 over 12 months, our calculation) or PlexusDx 6-month prepaid at $249 per month ($2,988 over 12 months, our calculation). Pomegranate Health's tirzepatide rate is $140 per month lower than PlexusDx month-to-month and $100 per month lower than PlexusDx's 6-month prepaid rate.
These calculations assume Pomegranate Health's advertised $119 semaglutide and $149 tirzepatide rates remain constant across all dose levels and that no additional fees appear at checkout. The evidence does not document renewal pricing or dose-tier pricing beyond the entry point, so confirm those details before committing to a full year.
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Decision factors: what the evidence documents and what it does not
Pomegranate Health strengths
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Lower advertised entry price: $119 per month for semaglutide and $149 per month for tirzepatide beat PlexusDx's month-to-month rates and match or undercut PlexusDx's 6-month prepaid rates without requiring upfront payment.
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Monthly billing: No multi-month commitment or large upfront cost; flexibility to pause or stop without forfeiting prepaid funds.
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No stated membership fee: Product page claims no membership or extra fee, which would keep the all-in monthly cost at the advertised medication price if confirmed at checkout.
Pomegranate Health gaps and uncertainties
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Dose-tier pricing not documented: Evidence confirms dose tiers exist in the app but does not provide pricing for 0.5 mg, 1.0 mg, 1.7 mg, or 2.4 mg weekly doses. If higher doses carry higher monthly costs, the year-long total will exceed $1,428.
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Fee-structure conflict: Historical materials mention a consult deposit; current product page says no membership or extra fee. The discrepancy was flagged for checkout confirmation. Readers should verify whether any consultation, visit, or onboarding charge applies.
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No captured review rating: A Trustpilot profile exists for Pomegranate Health, but rating and volume were not captured in this research pass. Service quality and customer-support responsiveness cannot be compared quantitatively.
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Renewal terms not explicit: Evidence documents a monthly-billed plan but does not specify auto-renewal terms, pause policies, or cancellation notice requirements.
PlexusDx strengths
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Flat-rate dosing: One published price covers all doses from starter through maintenance; no surprise increases as you titrate up.
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Verified review record: PlexusDx holds a 4.3-star rating on Trustpilot with 79% of reviews at five stars and 83% at four stars or higher, captured September 9, 2026 from trustpilot.com/review/plexusdx.com.
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Transparent multi-month discounts: Prepaid 3-month and 6-month plans lower the effective monthly cost to $169 and $149 respectively, with no hidden fees or dose-tier pricing.
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All-inclusive pricing: Provider visit, prescription, medication, and shipping included in the published rate; no separate consultation or membership charge.
PlexusDx gaps
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Higher month-to-month rate: $189 per month for semaglutide is $70 more than Pomegranate Health's $119 advertised rate, and $289 per month for tirzepatide is $140 more than Pomegranate Health's $149 rate.
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Prepay requirement for lowest rate: The $149 semaglutide and $249 tirzepatide per-month rates require $894 and $1,494 upfront respectively for six months; no monthly-billed option at those rates.
Choose Pomegranate Health if…
- The $119 semaglutide or $149 tirzepatide monthly rate fits your budget and you prefer not to prepay multiple months.
- You want flexibility to pause or stop treatment without forfeiting a large upfront payment.
- You are comfortable confirming the fee structure and dose-tier pricing at checkout, given the historical consult-deposit reference and the lack of documented higher-dose rates.
- You plan to stay at a low maintenance dose where the entry-level price may continue to apply.
Choose PlexusDx if…
- You want one published price that covers every dose level with no uncertainty about cost increases during titration or maintenance.
- Verified customer reviews matter to your decision; PlexusDx's 4.3-star Trustpilot rating with 83% of reviews at four stars or higher provides documented service-quality evidence.
- You can prepay six months and prefer the lower $149 semaglutide or $249 tirzepatide per-month rate, saving $360 to $600 per year compared to Pomegranate Health's monthly rate (our calculation, assuming Pomegranate Health's rate stays flat).
- You value transparent, all-inclusive pricing with no consultation or membership fees and no need to verify a fee structure at checkout.
Methodology and freshness
Pomegranate Health pricing was captured September 4, 2026 from the product page at joinpomegranate.com/products/compounded-semaglutide and the app pricing page at app.joinpomegranate.com/pricing. The $119 semaglutide and $149 tirzepatide figures represent advertised monthly rates with monthly billing and no documented prepay requirement. The product page states no membership or extra fee; historical materials mention a consult deposit, creating a documented conflict that readers should resolve at checkout. Dose-tier pricing exists in the app but was not captured; the rates in this article reflect entry-level pricing only.
PlexusDx pricing was captured July 17–23, 2026 from product pages at plexusdx.com. Month-to-month rates ($189 semaglutide, $289 tirzepatide) and multi-month prepaid rates (3-month: $169 sema / $269 tirz; 6-month: $149 sema / $249 tirz) are documented and verified. PlexusDx charges one flat rate at all dose levels with no membership fee.
All 12-month cost calculations are ours: we multiplied monthly rates by 12 or prepaid cycle costs by the number of cycles required to cover 12 months. Pomegranate Health calculations assume the advertised entry rate remains unchanged across dose increases; if higher doses cost more, the 12-month total will be higher than stated. PlexusDx calculations reflect the published flat rate at all doses. No eligibility, approval, dose, or treatment-duration outcome is guaranteed by either provider. All research was conducted September 13, 2026.
Frequently Asked Questions
Does Pomegranate Health charge a membership fee for semaglutide?
The product page captured September 4, 2026 states no membership or extra fee, and the documented membership/service monthly cost is $0. However, historical materials mention a consult deposit, creating a conflict. Confirm the complete fee structure—including any consultation, visit, or onboarding charges—at checkout before enrolling.
Does Pomegranate Health's $119 semaglutide price increase at higher doses?
Dose tiers are available in the Pomegranate Health app, but pricing for doses above the entry level was not captured in the evidence. The $119 figure is documented as a starter rate. Ask Pomegranate Health directly whether the monthly cost changes as you titrate to 0.5 mg, 1.0 mg, 1.7 mg, or 2.4 mg weekly.
How does Pomegranate Health's $119 semaglutide compare to PlexusDx over 12 months?
At the documented entry rates, Pomegranate Health semaglutide totals $1,428 over 12 months and PlexusDx month-to-month totals $2,268, a $840 difference in Pomegranate Health's favor (our calculation). PlexusDx's 6-month prepaid plan totals $1,788 over 12 months, $360 more than Pomegranate Health but with a flat rate at all doses and no fee-structure uncertainty.
Is Pomegranate Health semaglutide FDA-approved?
No. Pomegranate Health offers compounded semaglutide injection, which is not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. Branded Wegovy (semaglutide) is FDA-approved for chronic weight management; compounded semaglutide is not interchangeable with Wegovy.
Does PlexusDx charge the same price at every semaglutide dose?
Yes. PlexusDx publishes one flat rate per plan tier (month-to-month, 3-month, or 6-month) that applies to all doses from 0.25 mg starter through 2.4 mg maintenance. The month-to-month rate is $189 per month at every dose, and the 6-month prepaid rate is $149 per month at every dose, captured July 17–23, 2026.
Sources
- Pomegranate Health product page, joinpomegranate.com/products/compounded-semaglutide, accessed September 4, 2026
- Pomegranate Health app pricing page, app.joinpomegranate.com/pricing, accessed September 4, 2026
- PlexusDx semaglutide injection product page, plexusdx.com/products/semaglutide-injection, accessed July 17–23, 2026
- PlexusDx Trustpilot profile, trustpilot.com/review/plexusdx.com, accessed September 9, 2026
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Compounded medication disclosure: Compounded medications are not FDA-approved. The FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
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