Last reviewed: September 11, 2026 Last updated: September 11, 2026

Written by: Jay Hastings, CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.

The short answer

Fridays Health charges $389/month for compounded tirzepatide injection (month-to-month, captured at checkout September 4, 2026) and advertises $249/month for semaglutide (joinfridays.com/pricing, July 20, 2026; not yet verified at checkout in our dataset). Three providers deliver lower ongoing rates without prepayment: PlexusDx charges $289/month for tirzepatide and $189/month for semaglutide (month-to-month), Eden charges $298/month for tirzepatide and $198/month for semaglutide (medication $99 plus required $99/month membership), and Peak Wellness charges $349/month for tirzepatide and $249/month for semaglutide (month-to-month). Over 12 months with no prepayment, PlexusDx saves $1,200/year on tirzepatide and $720/year on semaglutide (vs Fridays' advertised semaglutide rate) compared to Fridays' month-to-month pricing. Fridays offers a richer support bundle—unlimited provider visits, 1-on-1 dietitian, mental-health coaching—included in its base rate; PlexusDx includes free pharmacist check-ins but no dietitian or mental-health services. Fridays' 12-month prepaid tirzepatide plan ($2,880 upfront, $240/month equivalent) undercuts PlexusDx's published 6-month rate ($249/month) by $9/month, but requires full-year commitment and upfront payment.

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At-a-glance comparison

Provider Semaglutide MTM Tirzepatide MTM Membership Support included
PlexusDx $189/mo $289/mo $0 Free PharmD check-in
Fridays Health $249/mo $389/mo $0 Unlimited visits, dietitian, mental-health coaching
Eden $198/mo $298/mo $99/mo (required) Coaching via membership
Peak Wellness $249/mo $349/mo $0 Provider visits included
Embody $299/mo $349/mo $0 Provider oversight included

Advertised on joinfridays.com/pricing July 20, 2026; not yet verified at checkout in our dataset. Medication $99 + required $99/month membership. All figures captured July–September 2026.

Month-to-month pricing normalized

Month-to-month plans let you pause or cancel without forfeiting prepaid funds. Here are the verified all-in monthly rates with no commitment:

Tirzepatide (compounded injection)

  • PlexusDx: $289/month → $3,468 over 12 months
  • Eden: $298/month (medication $99 + required $99 membership) → $3,576 over 12 months
  • Peak Wellness: $349/month → $4,188 over 12 months
  • Embody: $349/month → $4,188 over 12 months
  • Fridays Health: $389/month (captured at checkout September 4, 2026) → $4,668 over 12 months

PlexusDx saves $1,200/year vs Fridays ($389 − $289 = $100/month × 12), $108/year vs Eden, and $720/year vs Peak Wellness or Embody on tirzepatide month-to-month plans. (Our calculation.)

Semaglutide (compounded injection)

  • PlexusDx: $189/month → $2,268 over 12 months
  • Eden: $198/month (medication $99 + required $99 membership) → $2,376 over 12 months
  • Fridays Health: $249/month (advertised joinfridays.com/pricing July 20, 2026; not checkout-verified in our dataset) → $2,988 over 12 months
  • Peak Wellness: $249/month → $2,988 over 12 months
  • Henry Meds: $297/month → $3,564 over 12 months
  • Embody: $299/month → $3,588 over 12 months

PlexusDx saves $720/year vs Fridays' advertised semaglutide rate ($249 − $189 = $60/month × 12) and $108/year vs Eden. (Our calculation.) We captured Fridays' $249 semaglutide figure from its pricing page in July 2026 but have not yet verified it at checkout; confirm at joinfridays.com before committing.

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Prepaid and promotional plans

Fridays Health offers prepaid subscriptions that lower the effective monthly rate in exchange for upfront payment and commitment:

  • 3-month prepaid: $896 upfront ($298.67/month equivalent over 3 months)
  • 4-for-3 promotional plan: $896 upfront, commit to 3 months, fourth month free = $224/month equivalent over 4 months
  • 6-month prepaid: $1,650 upfront ($275/month equivalent)
  • 12-month prepaid: $2,880 upfront ($240/month equivalent)

All figures captured at checkout September 4, 2026. The 4-for-3 plan is a promotional offer; we have no evidence of renewal terms beyond the initial cycle. If you continue month-to-month after the promotional period, the rate reverts to $389/month. Assuming one promotional cycle followed by eight months at $389, the 12-month total is $896 + ($389 × 8) = $4,008 ($334/month average over 12 months, our calculation).

PlexusDx publishes standing multi-month rates with no promotional lock-in:

  • Tirzepatide injection 6-month rate: $249/month → $2,988 over 12 months
  • Semaglutide injection 6-month rate: $149/month → $1,788 over 12 months

Fridays' 12-month prepaid tirzepatide plan ($2,880) saves $108/year vs PlexusDx's 6-month rate ($2,988), but requires $2,880 upfront and a 12-month commitment. PlexusDx's 6-month rate is a published standing rate with no 12-month prepay requirement. (Our calculation.)

What you get for the price

Fridays Health

Fridays' all-inclusive rate covers:

  • Compounded semaglutide or tirzepatide injection
  • Unlimited provider visits (no per-visit charge)
  • 1-on-1 dietitian support
  • Mental-health coaching
  • Dedicated care coach
  • Required labs at no extra charge (comprehensive metabolic panel, hemoglobin A1C, TSH, lipid panel documented July 20, 2026)
  • Free shipping
  • $0 membership fee

Fridays bundles clinical oversight and behavioral support into a single monthly charge. The $100/month premium over PlexusDx's tirzepatide rate buys unlimited clinician access, dietitian consultations, and mental-health coaching—a meaningful difference if you want structured behavioral support alongside medication.

PlexusDx

PlexusDx's all-inclusive rate covers:

  • Online provider visit and prescription review
  • Compounded medication (five formats: semaglutide injection, tirzepatide injection, semaglutide oral, tirzepatide oral, microdose GLP-1)
  • Free pharmacist (PharmD) check-in
  • Shipping
  • $0 membership fee
  • Optional DNA testing: $99 for program members, $298 general public (captured July 2026)

PlexusDx does not include dietitian or mental-health coaching in its base rate. Clinical oversight is provider-led with pharmacist support; behavioral coaching is not part of the package.

Eden

Eden charges $99/month for medication plus a required $99/month membership ($198 semaglutide, $298 tirzepatide total). The membership includes coaching and clinical oversight. Eden's tirzepatide rate is $9/month higher than PlexusDx and $91/month lower than Fridays month-to-month.

Peak Wellness and Embody

Peak Wellness charges $249/month semaglutide and $349/month tirzepatide (month-to-month, captured July 2026); Embody charges $299 semaglutide and $349 tirzepatide. Both include provider oversight; neither advertises separate membership fees. Peak Wellness ties Fridays' advertised semaglutide rate and saves $40/month vs Fridays on tirzepatide; Embody saves $40/month on tirzepatide vs Fridays but charges $50/month more than Fridays' advertised semaglutide rate.

Pricing stability and verification gaps

Fridays' pricing appears campaign-dependent. We captured $389/month tirzepatide at checkout on September 4, 2026, but Fridays advertised $359/month on joinfridays.com/pricing in July 2026—a $30 difference. The site also advertised promotional figures as low as $117 semaglutide and $190 tirzepatide (captured September 4, 2026) that require prepayment or multi-month commitment but did not specify the terms on the landing page we reviewed. We have not yet verified Fridays' $249/month semaglutide figure at checkout; it appeared on the pricing page in July but not in our September checkout dataset. Confirm all Fridays rates at checkout before committing.

PlexusDx publishes standing rates on product pages with no promotional tiers; the figures in this article match the rates on plexusdx.com as of September 11, 2026.

Choose PlexusDx if…

  • You want the lowest month-to-month rate on tirzepatide ($289) or semaglutide ($189) with no prepayment
  • You prefer transparent, published pricing over campaign-dependent promotional figures
  • You want format flexibility: PlexusDx offers semaglutide and tirzepatide in both injection and oral forms, plus a microdose injection option ($129/month) for maintenance or titration
  • Clinical oversight and pharmacist check-ins meet your support needs, and you don't require bundled dietitian or mental-health coaching
  • You want the option to add DNA testing ($99 for program members) to inform medication and dose selection

Choose Fridays Health if…

  • You want unlimited provider visits, 1-on-1 dietitian support, and mental-health coaching bundled into your monthly rate
  • You're willing to pay $100/month more (tirzepatide month-to-month) for structured behavioral support alongside medication
  • You can commit to 12 months upfront and want the lowest prepaid rate on tirzepatide ($240/month, $2,880 prepaid)—this beats PlexusDx's published 6-month rate by $9/month but requires full-year payment at enrollment
  • You prefer a dedicated care coach and comprehensive lab panel ($0 lab fees advertised) included in the base rate

Choose Eden if…

  • You want a middle-ground price: Eden's $298/month tirzepatide (medication + required membership) is $9/month higher than PlexusDx and $91/month lower than Fridays month-to-month
  • You want coaching included but don't need the full dietitian + mental-health bundle Fridays offers
  • The required $99/month membership fee is acceptable in exchange for clinical and coaching support

Choose Peak Wellness or Embody if…

  • Peak Wellness ($349 tirzepatide, $249 semaglutide) or Embody ($349 tirzepatide, $299 semaglutide) pricing fits your budget and you want provider oversight with no separate membership fee
  • You prefer a month-to-month plan with moderate pricing between PlexusDx's low end and Fridays' high end

Medication formats and regulatory status

All providers in this comparison dispense compounded semaglutide and tirzepatide. Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

PlexusDx offers five formats: semaglutide injection ($189 month-to-month), tirzepatide injection ($289 month-to-month), semaglutide oral capsules ($289 month-to-month), tirzepatide oral capsules ($349 month-to-month), and microdose GLP-1 injection ($129 month-to-month). Fridays, Eden, Peak Wellness, and Embody offer compounded injections; we have not captured oral or microdose options in their product lines as of September 2026.

Methodology and freshness

We captured Fridays Health pricing at checkout on September 4, 2026, and from joinfridays.com/pricing on July 20, 2026. PlexusDx pricing reflects published rates on plexusdx.com as of September 11, 2026. Eden, Peak Wellness, Embody, and Henry Meds rates were verified at checkout between July 17 and July 23, 2026. All 12-month cost calculations, monthly equivalents for prepaid plans, and year-over-year savings figures are our calculations derived from the captured rates. We label advertised figures that we have not yet verified at checkout and note when pricing appears campaign-dependent. Fridays' $249 semaglutide month-to-month rate is advertised but not yet checkout-verified in our dataset; readers should confirm at joinfridays.com. PlexusDx publishes this comparison and applies the same evidence rules to its own program and competing programs.

Frequently Asked Questions

Does PlexusDx include dietitian or mental-health coaching like Fridays Health?

No. PlexusDx includes free pharmacist check-ins and provider oversight but does not bundle dietitian or mental-health coaching in its base rate. Fridays Health includes unlimited provider visits, 1-on-1 dietitian support, and mental-health coaching in its $389/month tirzepatide and $249/month semaglutide rates (advertised). The $100–$60/month difference reflects the cost of that support bundle.

Why does Fridays advertise multiple prices for the same medication?

Fridays' pricing is campaign-dependent. We captured $389/month tirzepatide at checkout in September 2026, $359/month advertised on the pricing page in July 2026, and promotional figures as low as $190/month tirzepatide and $117/month semaglutide that require prepayment or multi-month commitment. Confirm the rate and terms at joinfridays.com before enrolling.

Is Fridays' 12-month prepaid tirzepatide rate cheaper than PlexusDx?

Yes, by $108/year. Fridays charges $2,880 upfront for 12 months ($240/month equivalent); PlexusDx's published 6-month tirzepatide rate is $249/month ($2,988 over 12 months, our calculation). Fridays' rate requires full-year commitment and upfront payment; PlexusDx's 6-month rate is a standing published rate with no 12-month prepay requirement.

Does Eden's membership fee cover anything beyond medication?

Yes. Eden's required $99/month membership includes coaching and clinical oversight. The total monthly cost is $198 for semaglutide (medication $99 + membership $99) and $298 for tirzepatide (medication $99 + membership $99). You cannot purchase Eden medication without the membership.

Can I switch providers mid-treatment if I find a cheaper rate?

Switching telehealth providers is possible but not guaranteed. The new provider's clinician must review your history and determine whether continuing your current medication and dose is appropriate. Some providers require titration from a lower starting dose regardless of your current regimen. Prepaid subscriptions are typically non-refundable, so switching before a prepaid term ends means forfeiting the remaining balance.

Sources

  • Fridays Health pricing page (joinfridays.com/pricing), accessed July 20, 2026
  • Fridays Health checkout pricing capture, September 4, 2026
  • PlexusDx product pages (plexusdx.com), accessed September 11, 2026
  • PlexusDx Trustpilot profile (trustpilot.com/review/plexusdx.com), accessed September 9, 2026
  • Eden, Peak Wellness, Embody, Henry Meds checkout pricing captures, July 17–23, 2026

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Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed 503A compounding pharmacies.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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