Last reviewed: September 6, 2026
Last updated: September 6, 2026
Written by: Jay Hastings, CEO of PlexusDx
Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.
Medically reviewed by: Jayden Lee, PharmD, EMBA
Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.
PlexusDx publishes this comparison and is one of the providers discussed. We use the same evidence rules for our own program and competing programs.
The short answer
Henry Meds offers sublingual semaglutide tablets at $249/month month-to-month or $149/month when you prepay twelve months ($1,788 upfront). A second tier labeled "premium semaglutide tablets/drops" is listed at $179/month month-to-month, though source documentation shows identical prepaid pricing to the $249 tier—the distinction between tiers is not fully explained. Henry also offers injectable semaglutide and compounded liraglutide; this article focuses on oral and sublingual semaglutide routes because the topic concerns oral alternatives.
Among alternatives, PlexusDx charges $289/month month-to-month for oral semaglutide capsules ($249/month on a six-month plan, billed $1,494 every six months). Eden advertises $99/month medication-only but requires a separate $99/month membership, making the ongoing all-in cost $198/month. Peak Wellness charges $249/month, Embody $299/month, and TrimRx $299/month at verified checkout despite a $199 advertised rate. Found offers month-to-month cash at $289/month or $169/month equivalent when you prepay twelve months. Fridays and MEDVi appear at $249/month and $299/month respectively but are not yet checkout-verified. Henry's prepaid rates beat most alternatives when you commit twelve months; PlexusDx and Eden offer lower month-to-month costs if you prefer payment flexibility.
Comparing oral GLP-1 formats and routes?
PlexusDx offers both sublingual (dissolves under the tongue) and swallowable capsule formats—review which route fits your preference.
Explore oral and injectable options →
At-a-glance: oral semaglutide pricing compared
| Provider |
Route |
Month-to-month |
Prepaid option |
12-month total (our calculation) |
| Henry Meds |
Sublingual tablets |
$249/month |
$149/month equivalent ($1,788 paid in full for 12 months) |
$2,988 (MTM) or $1,788 (prepaid) |
| Henry Meds |
"Premium" tablets/drops |
$179/month |
$149/month equivalent ($1,788 paid in full for 12 months) |
$2,148 (MTM) or $1,788 (prepaid) |
| PlexusDx |
Oral capsule |
$289/month |
$249/month ($1,494 every 6 months) |
$3,468 (MTM) or $2,988 (6-month plan) |
| Eden |
Oral capsule |
$198/month all-in ($99 medication + $99 membership) |
None observed |
$2,376 |
| Peak Wellness |
Oral capsule |
$249/month |
Lower rates on 6-month prepaid (specific figure not yet verified) |
$2,988 (MTM) |
| Embody |
Oral capsule |
$299/month |
None observed |
$3,588 |
| Found |
Oral capsule |
$289/month cash |
$169/month equivalent (12-month prepaid) |
$3,468 (MTM) or $2,028 (prepaid) |
| TrimRx |
Oral capsule |
$299/month (verified checkout; advertised $199) |
Lower rates on 3-, 6-, and 12-month plans charged upfront |
$3,588 (MTM) |
| Fridays |
Oral capsule |
$249/month |
None observed |
$2,988 (not yet checkout-verified) |
| MEDVi |
Oral capsule |
$299/month (shown after questionnaire) |
None observed |
$3,588 (not yet checkout-verified) |
Prices captured July–September 2026. Month-to-month rates are verified ongoing costs; prepaid equivalents are our calculation and require the full term paid upfront. All prices include medication, provider visits, and shipping unless noted otherwise.
Henry Meds oral semaglutide: two tiers, prepaid advantage
Henry Meds markets sublingual semaglutide tablets—medication that dissolves under the tongue—at $249/month when billed monthly. A lower-priced tier labeled "premium semaglutide tablets/drops" appears at $179/month month-to-month. Both tiers show identical prepaid pricing in the captured source data: $169/month equivalent when you prepay six months ($1,014 upfront) or $149/month equivalent when you prepay twelve months ($1,788 upfront). The distinction between the $249 and $179 tiers is not explained in available documentation, and readers considering either tier should confirm dosing protocol, formulation differences, and eligibility at intake.
Over twelve months, Henry's sublingual tablets cost $2,988 month-to-month or $1,788 when prepaid annually—a $1,200 difference. The "premium" tier runs $2,148 month-to-month or the same $1,788 prepaid. Henry also offers injectable semaglutide ($297/month month-to-month, $197/month equivalent on a twelve-month prepaid plan) and compounded liraglutide ($179/month month-to-month, $119/month equivalent prepaid), but those fall outside this oral-route comparison.
Henry bundles medication, provider visits, shipping, and supplies in the subscription price. No separate membership fee applies. Cancellation is permitted anytime on month-to-month plans through the patient portal, email, or phone; multi-month prepaid plans may require paying the remaining balance unless a provider determines medical reasons prevent continuation. Henry works with licensed U.S. compounding pharmacies operating under Section 503A or outsourcing-facility registration.
Henry Meds holds a 4.4-star rating on Trustpilot across approximately 13,000 reviews captured September 4, 2026. No dominant negative themes emerged in the review-analysis pass.
PlexusDx oral semaglutide: capsule format, mid-tier month-to-month
PlexusDx offers oral semaglutide in swallowable capsule form at $289/month month-to-month, $269/month on a three-month plan (billed $807 every three months), or $249/month on a six-month plan (billed $1,494 every six months). Over twelve months the cost is $3,468 month-to-month or $2,988 on the six-month recurring plan—our calculation. PlexusDx does not currently offer a twelve-month prepaid option for oral semaglutide, so direct comparison to Henry's $1,788 annual prepaid rate requires weighing payment flexibility against upfront commitment.
PlexusDx capsules are swallowed with water rather than dissolved under the tongue. Dosing follows the same titration schedule used for injectable GLP-1 agonists, and the price remains constant at every dose level. The subscription includes medication, provider review, and shipping; no membership fee applies. An optional genetic-testing add-on ($298, or $99 for program members) pairs genetic testing with a free pharmacist check-in to identify medication-response variants, though the add-on does not change the semaglutide prescription itself.
PlexusDx works with licensed Section 503A compounding pharmacies. You can cancel anytime on the monthly plan. PlexusDx holds a 4.3-star rating on Trustpilot, with 79% of reviews at five stars and 83% at four stars or higher (captured September 9, 2026).
Eden, Peak Wellness, Embody, and TrimRx: $198–$299 month-to-month
Eden advertises oral semaglutide at $99/month medication-only, but a separate $99/month membership is required, bringing the ongoing all-in cost to $198/month—$2,376 over twelve months (our calculation). Eden offers the lowest verified month-to-month rate in this comparison but does not publish prepaid discounts. The two-part billing structure means canceling medication does not automatically cancel the membership, so confirm termination procedures before enrollment.
Peak Wellness charges $249/month for oral semaglutide with no membership fee and advertises lower per-month rates on six-month prepaid plans, though specific prepaid figures are not yet checkout-verified. At the standard month-to-month rate Peak Wellness runs $2,988 annually, matching PlexusDx's six-month plan cost and Henry's standard sublingual tablet month-to-month cost.
Embody lists oral semaglutide at $299/month with no membership fee and the same price at every dose—$3,588 over twelve months (our calculation). Embody does not publish prepaid options in captured sources. The rate is $10/month higher than PlexusDx month-to-month and $50/month higher than Henry's standard sublingual tier.
TrimRx advertises $199/month for oral semaglutide but verified checkout showed $299/month (captured July 20, 2026). TrimRx offers lower per-month rates on three-, six-, and twelve-month plans charged upfront, but specific prepaid figures are not yet verified. At $299/month the annual cost is $3,588, matching Embody.
Found: insurance and cash tracks, twelve-month prepaid discount
Found operates two tracks: an insurance-supported path advertised "from $99/month" and a cash-pay path starting at $289/month month-to-month for oral semaglutide. The cash track offers a twelve-month prepaid plan at $169/month equivalent, requiring the full twelve-month payment upfront—total cost $2,028 over twelve months (our calculation). That prepaid rate sits $240 above Henry's twelve-month prepaid rate, but $960 below PlexusDx's twelve-month cost on the six-month recurring plan.
Found also charges $359/month for oral tirzepatide on the cash track. The insurance track's $99 floor depends on formulary coverage, prior authorization, and plan design; out-of-pocket costs vary by insurer and are not guaranteed. Found bundles dietitian support and app-based tracking in the subscription.
Normalized like-for-like: month-to-month and twelve-month totals
| Provider |
Month-to-month rate |
12-month MTM total |
Best 12-month prepaid total |
| Henry Meds (sublingual tablets) |
$249 |
$2,988 |
$1,788 (paid in full) |
| Henry Meds ("premium" tier) |
$179 |
$2,148 |
$1,788 (paid in full) |
| Eden |
$198 ($99 + $99 membership) |
$2,376 |
None observed |
| Found (cash) |
$289 |
$3,468 |
$2,028 (paid in full) |
| Peak Wellness |
$249 |
$2,988 |
Lower on 6-month prepaid (not yet verified) |
| PlexusDx |
$289 |
$3,468 |
$2,988 (6-month recurring plan) |
| Embody |
$299 |
$3,588 |
None observed |
| TrimRx |
$299 (verified checkout) |
$3,588 |
Lower on prepaid (not yet verified) |
All twelve-month totals are our calculation. Prepaid figures require the full term paid upfront and may carry early-termination restrictions.
Start with month-to-month oral semaglutide at $289
A licensed provider reviews your intake and determines whether a prescription is appropriate—no payment until approval.
Start My 60-Second Intake →About 60 seconds · $0 charged until provider approval.
Decision factors: route, budget, commitment, and compounding transparency
Administration route: Henry Meds sublingual tablets dissolve under the tongue; PlexusDx, Eden, Peak Wellness, Embody, TrimRx, Found, Fridays, and MEDVi use swallowable capsules. Sublingual absorption bypasses first-pass hepatic metabolism, which may alter pharmacokinetics, but no head-to-head efficacy trials comparing sublingual and oral-capsule semaglutide are cited in the source packet. Patient preference for administration method is a legitimate decision input.
Month-to-month flexibility versus prepaid savings: Eden offers the lowest verified month-to-month all-in rate ($198) but no prepaid discount. Henry's $179 "premium" tier sits $19/month higher month-to-month but drops to $149/month equivalent ($1,788 annually) when prepaid twelve months. PlexusDx's $289 month-to-month is $91 higher than Eden but includes cancel-anytime flexibility; PlexusDx's six-month plan ($249/month, $2,988 annually) beats Eden's twelve-month total by $612 but requires $1,494 charged every six months. Henry's twelve-month prepaid ($1,788) is the lowest annual cost in this comparison, $240 below Found's twelve-month prepaid and $1,200 below PlexusDx's six-month plan total.
Compounding pharmacy class: Henry Meds works with both Section 503A and outsourcing-facility pharmacies; PlexusDx exclusively partners with Section 503A pharmacies. The Section 503A designation indicates patient-specific compounding under a licensed prescriber's order, while outsourcing facilities operate under separate registration and may compound without individual prescriptions. Both classes are licensed and inspected, but the regulatory frameworks differ. Readers prioritizing Section 503A compounding should confirm pharmacy class at intake.
Prepaid early-termination risk: Henry's cancellation policy permits anytime cancellation on month-to-month plans but states that multi-month prepaid subscribers "may be required to pay out the rest of your balance unless you're unable to continue for medical-related reasons as determined by a healthcare provider." Found, TrimRx, and Peak Wellness advertise prepaid discounts but do not publish termination terms in captured sources. Readers considering prepaid plans should request written refund and termination policies before payment.
Advertised versus checkout pricing: TrimRx advertised $199/month but checkout verified $299/month (July 20, 2026). Fridays ($249/month) and MEDVi ($299/month) are not yet checkout-verified. Eden's $99 medication figure excludes the mandatory $99 membership. Confirm final pricing at checkout before enrollment.
Choose Henry Meds if…
You prefer sublingual administration, can commit twelve months upfront, and want the lowest verified annual cost in this comparison ($1,788 for either tier when prepaid). Henry's 4.4-star Trustpilot rating across ~13,000 reviews and the absence of dominant negative themes in recent captures suggest stable service delivery. The $1,200 difference between Henry's twelve-month prepaid and month-to-month rates is the steepest discount observed, making prepayment financially attractive if your clinical picture supports a year-long protocol. Confirm which tier—$249 sublingual or $179 "premium"—matches your dosing needs, and request written confirmation of formulation differences before enrollment.
Choose Eden if…
You want the lowest verified month-to-month all-in cost ($198) without prepayment and prefer capsule format over sublingual. Eden's two-part billing ($99 medication + $99 membership) means you carry both charges as long as you remain enrolled; canceling medication does not automatically cancel membership. Over twelve months Eden's $2,376 total sits $588 above Henry's prepaid rate but $612 below PlexusDx's six-month plan. Eden suits cost-conscious subscribers who value payment flexibility over long-term discounts and will manage two recurring line items.
Choose Peak Wellness, Embody, or TrimRx if…
You are already established with one of these providers and prefer continuity, or their care model—coaching frequency, app interface, or provider network—aligns with your preferences. Peak Wellness ($249/month) matches Henry's standard sublingual month-to-month rate and advertises six-month prepaid savings, though figures are not yet verified. Embody ($299/month) and verified TrimRx ($299/month) sit at the higher end of the month-to-month range and show no verified prepaid discounts in captured sources. None of these three offers a lower twelve-month total than Henry's prepaid or Eden's month-to-month rate, so the choice hinges on non-price factors: existing relationship, care-team rapport, or platform features.
Choose Found if…
You value integrated dietitian support and app-based tracking alongside medication, or you have insurance coverage that brings out-of-pocket cost near the advertised $99/month floor. Found's cash-pay month-to-month ($289) matches PlexusDx and sits $91 above Eden; Found's twelve-month prepaid ($2,028) is $240 above Henry's prepaid but $960 below PlexusDx's six-month recurring total. The dietitian and behavior-change platform may justify the premium for subscribers who benefit from frequent coaching. Confirm insurance authorization timeline and formulary coverage before relying on the $99 figure.
Where PlexusDx fits
PlexusDx oral semaglutide costs $289/month month-to-month or $249/month on a six-month plan ($2,988 annually)—$91/month higher than Eden month-to-month, $40/month higher than Peak Wellness, $10/month lower than Embody and TrimRx, and matching Found's cash month-to-month rate. PlexusDx's annual cost on the six-month plan is $1,200 above Henry's twelve-month prepaid but $612 below Eden's twelve-month month-to-month total and $960 below Found's prepaid.
PlexusDx uses swallowable capsules rather than sublingual tablets and works exclusively with Section 503A pharmacies. The six-month plan offers moderate savings without requiring a full year upfront; payment recurs every six months rather than locking in twelve months of commitment. Cancel-anytime flexibility on the monthly plan accommodates exploratory starts or transitions from other protocols. The optional genetic-testing add-on ($99 for program members) identifies genetic variants affecting semaglutide metabolism, side-effect risk, and dose response, paired with a free pharmacist consultation—a feature not observed in Henry, Eden, Peak Wellness, Embody, TrimRx, or Found source materials.
PlexusDx also offers injectable semaglutide at $189/month month-to-month ($149/month on a six-month plan), injectable tirzepatide at $289/month month-to-month ($249/month on a six-month plan), oral tirzepatide capsules at $349/month month-to-month ($279/month on a six-month plan), and a microdose GLP-1 injectable protocol at $129/month month-to-month. Readers interested in route flexibility—sublingual, oral capsule, or injection—or planning a future switch between compounds can consolidate care under one provider rather than moving between platforms.
Methodology and freshness
Pricing for Henry Meds was captured July 20 and September 4, 2026, from the provider's public website and cart flows. PlexusDx pricing is internal and current as of September 6, 2026. Eden, Peak Wellness, Embody, Found, TrimRx, Fridays, and MEDVi figures were captured July 20, 2026; TrimRx and Eden rates are checkout-verified, while Fridays and MEDVi are not yet verified. Trustpilot ratings for Henry Meds and PlexusDx were captured September 4, 2026. Twelve-month totals, prepaid monthly equivalents, and all comparisons labeled "our calculation" derive from the stated rates using standard arithmetic and assume continuous enrollment; we do not apply unstated discounts or promotional codes. Readers should confirm current pricing, pharmacy class, cancellation terms, formulation differences between Henry's two oral tiers, and eligibility at intake before enrollment.
Frequently Asked Questions
What is the difference between sublingual and oral semaglutide?
Sublingual semaglutide dissolves under the tongue and enters the bloodstream directly through the mucosa, bypassing first-pass liver metabolism. Oral semaglutide capsules are swallowed and absorbed in the gastrointestinal tract. Both routes deliver the same active compound, but pharmacokinetics may differ. No head-to-head efficacy trials are cited in available evidence, so choice depends on administration preference and provider guidance.
Does Henry Meds charge separately for provider visits or shipping?
No. Henry Meds bundles medication, provider visits, shipping, and supplies in the subscription price. No separate membership fee applies. Multi-month prepaid plans may require paying the remaining balance if you cancel early, unless a provider determines medical reasons prevent continuation.
Can I switch from Henry Meds to PlexusDx mid-protocol?
Switching providers mid-protocol requires a new intake and provider review at PlexusDx. The new provider determines whether to continue your current dose or adjust titration based on your history and tolerance. Timing the switch to align with your current refill cycle avoids overlapping medication shipments. Neither Henry nor PlexusDx guarantees uninterrupted transfers or specific starting doses.
Why does Eden show $99/month oral semaglutide when the all-in cost is $198?
Eden charges $99/month for medication and a separate $99/month membership fee, so the ongoing all-in cost is $198/month. The medication-only figure appears in some marketing placements. Canceling medication does not automatically cancel the membership; you must terminate both subscriptions separately to stop all charges.
Which provider offers the lowest twelve-month cost for oral semaglutide?
Henry Meds offers the lowest verified twelve-month cost at $1,788 when you prepay the full year upfront for either the $249/month sublingual tablets or the $179/month "premium" tier. Found's twelve-month prepaid is $2,028, Eden's month-to-month total is $2,376, and PlexusDx's six-month recurring plan totals $2,988 over twelve months—all our calculation.
Sources
- Henry Meds public website and product pages (captured July 20, 2026, and September 4, 2026)
- Henry Meds FAQ and cancellation policy (captured September 6, 2026)
- PlexusDx internal pricing and product specifications (current as of September 6, 2026)
- Eden, Peak Wellness, Embody, Found, TrimRx, Fridays, and MEDVi public websites and checkout flows (captured July 20, 2026)
- Trustpilot reviews for Henry Meds and PlexusDx (captured September 4, 2026)
Ready to compare PlexusDx oral semaglutide to your current program?
One all-inclusive price covers your online provider visit, prescription, medication, and shipping—no membership, no hidden fees. Complete a short intake and a licensed provider reviews your fit.
Start My Intake →
Compounded medication disclosure: Compounded medications are not FDA-approved. FDA does not review compounded drugs before marketing for safety, effectiveness, or quality. A licensed clinician determines whether a prescription is appropriate for an individual patient. PlexusDx works with licensed Section 503A compounding pharmacies.
Medical and Editorial Standards
Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.
Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.
Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.
Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.
Share:
Best Mochi Health Alternatives for Flat-Rate GLP-1 Pricing in 2026
Best Eden Alternatives for GLP-1 Weight Loss in 2026 — 2026 Verified