The Precision Peptide Genetic Test analyzes SULT1A1 — the sulfotransferase enzyme that runs a methylation-independent route to estrogen clearance. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your SULT1A1 Arg213His genotype determines how quickly sulfation neutralizes estradiol and its metabolites for excretion — a parallel Phase 2 pathway that COMT genetics alone cannot capture.