History of GLP-1 Drugs: Complete Timeline From Exenatide (2005) to Tirzepatide and Beyond
The complete history of GLP-1 drugs — from 1902 incretin research to exenatide (2005), Victoza (2010), Ozempic (2017), Rybelsus (2019), Wegovy (2021), Mounjaro (2022), Zepbound (2023), and pipeline candidates orforglipron — with where PlexusDx Semaglutide, Tirzepatide, Microdose, and GLP-Squared protocols fit in 2026.
GLP-1 Pros and Cons (2026): Benefits, Risks, Costs & PlexusDx Options
The honest 2026 trade-off on GLP-1 medications: substantial weight loss and cardiometabolic benefits balanced against GI side effects, cost, lean-mass loss risk, and long-term maintenance. Compares branded vs compounded options and where PlexusDx Weight Management Protocols fit at $129/mo to $349/mo across six protocols.
Mounjaro Side Effects and PlexusDx Tirzepatide Oversight (2026)
Mounjaro side effects from the FDA-approved label — common GI reactions (nausea, vomiting, diarrhea, constipation, abdominal pain), less common serious reactions (pancreatitis, gallbladder disease, acute kidney injury), and the boxed warning for thyroid C-cell tumors with MTC and MEN 2 contraindications. Plus how compounded tirzepatide protocol oversight from PlexusDx Tirzepatide Injection ($289/mo) and Tirzepatide Oral ($349/mo) compares, and where the Precision Peptide Genetic Test fits as $298 for GIPR, FTO, MC4R, and TCF7L2 baseline.
