Fridays Health offers tirzepatide at $389/month or as low as $224/month on prepaid plans. We compare five plan structures, calculate 12-month totals, and show when prepayment saves money versus when month-to-month flexibility wins.

BrightMeds' promotional 3-month plans cost substantially less than PlexusDx month-to-month, but the offer is state-limited and labeled a summer special. We compare plan terms, inclusions, medication options, and 12-month costs so you can weigh promotional pricing against established programs.

AltRx advertised promotional semaglutide pricing starts lower than PlexusDx, but that pricing expired September 5, 2026, prepaid plans require full upfront payment, and customer reports conflict with advertised cancellation terms.

Fifty410 charges $399–$549 upfront for three months of tirzepatide; Brello rebills $499 every 11 weeks. Both require prepayment. We compare effective monthly costs, billing structures, and dose flexibility across both services and PlexusDx's $269/month three-month plan.