Female patient discussing GSTM1, GSTT1, glutathione, and hormone detox genetics — PlexusDx Precision Peptide Genetic Test

GSTM1 and GSTT1: Glutathione and Hormone Detox Genetics

The Precision Peptide Genetic Test analyzes GSTM1 and GSTT1 — the glutathione S-transferase genes whose null deletions eliminate the tertiary Phase 2 backstop against reactive estrogen quinones. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your GSTM1 and GSTT1 deletion status determines whether glutathione conjugation is available when COMT and SULT1A1 clearance is insufficient.

Healthy adult representing the genes that affect glutathione production — PlexusDx Precision Peptide Genetic Test

What Genes Affect Glutathione Production? Your Genetic Guide

Glutathione synthesis, recycling, and detoxification capacity are all genetically variable — GCLC, GCLM, GSR, GPX1, GSTM1, and NFE2L2 each shape a different step. The Precision Peptide Genetic Test maps these variants across 14 pathways, 49 peptides, and 150+ genetic insights, revealing where your antioxidant production is genetically strongest and where it leaks.