Fit athlete representing the genes that affect growth hormone response — PlexusDx Precision Peptide Genetic Test

What Genes Affect Growth Hormone Response?

Multiple genes shape growth hormone response — from GHSR, which triggers GH pulses from the pituitary, to IGF1, which converts that signal into anabolic action, to ACTN3 and MSTN, which determine what the signal builds. The Precision Peptide Genetic Test analyzes all of them as part of 15 Muscle Growth insights across 14 pathways, 49 peptides, and 150+ genetic insights.

Fit adult representing genetics of the growth hormone axis peptide response — PlexusDx Precision Peptide Genetic Test

How Your Genetics Shape Growth Hormone Axis Peptide Response

Your response to growth hormone axis pathways isn’t shaped by a single gene — it’s the product of at least eight interacting genetic factors, from GH release (GHSR) to fiber architecture (ACTN3) to recovery capacity (IL-6). The Precision Peptide Genetic Test analyzes all as part of 15 Muscle Growth insights across 14 pathways, 49 peptides, and 150+ genetic insights.

Fit adult representing GHSR ghrelin receptor genetics and growth hormone release — PlexusDx Precision Peptide Genetic Test

The GHSR Ghrelin Receptor: Genetics of GH Release

The GHSR gene encodes the ghrelin receptor — the trigger that initiates growth hormone pulses from the pituitary. GHSR variants shape the amplitude and frequency of GH output upstream of IGF-1 production. The Precision Peptide Genetic Test analyzes GHSR as one of 15 Muscle Growth insights across 14 pathways, 49 peptides, and 150+ genetic insights.

Fit athlete representing genetic muscle growth testing and 15 pathway insights — PlexusDx Precision Peptide Genetic Test

Complete Guide to Genetic Muscle Growth Testing: 15 Pathway Insights

The Precision Peptide Genetic Test analyzes 15 muscle growth insights — ACTN3, IGF1, MSTN, GHSR, and GHR — within a panel of 14 pathways, 49 peptides, and 150+ genetic insights. This pillar guide breaks down each muscle gene, what it reveals about fiber type and growth response, and why your DNA is the most underused variable in any muscle protocol.

Fit mature adult representing growth hormone axis genetics — IGF1, GHSR, and aging — PlexusDx Precision Peptide Genetic Test

Growth Hormone Axis Genetics: IGF1, GHSR, and Aging

Growth hormone axis output declines with age — a process called somatopause. GHSR variants determine GH pulse sensitivity. IGF1 variants set downstream anabolic signal baseline. GHR variants shape how efficiently GH converts to IGF-1. The Precision Peptide Genetic Test analyzes all three as part of 17 Longevity & Aging insights spanning 14 pathways, 49 peptides, and 150+ genetic insights.