Female patient discussing CYP1A1 and CYP1B1 estrogen metabolism pathways — PlexusDx Precision Peptide Genetic Test

CYP1A1 and CYP1B1: Estrogen Metabolism Pathways Explained

The Precision Peptide Genetic Test analyzes CYP1A1 and CYP1B1 — the two Phase 1 enzymes that determine which metabolic route estradiol takes after it leaves circulation. Part of 14 pathways, 49 peptides, and 150+ genetic insights, your CYP1A1 and CYP1B1 variants set the 2-OHE2 to 4-OHE2 ratio that shapes your estrogen biology from the inside out.

Clinician reviewing women's hormone genetic testing with a female patient — PlexusDx Precision Peptide Genetic Test

Complete Guide to Genetic Women's Hormone Testing: 6 Pathway Insights

The Precision Peptide Genetic Test analyzes 6 Reproductive Health insights covering women's hormone pathways — COMT, CYP1A1, CYP1B1, MTHFR, ESR1, and Phase 2 detox genes — within a panel of 14 pathways, 49 peptides, and 150+ genetic insights. This pillar guide breaks down how you produce, clear, and respond to estrogen, and why clearance genetics matter as much as production.