Male patient discussing whether genetic testing can predict TRT response — PlexusDx Precision Peptide Genetic Test

Can Genetic Testing Predict TRT Response? What It Actually Tells You

Not exactly — but the answer matters. The Precision Peptide Genetic Test doesn't predict whether a specific androgen protocol will work. It maps six biological variables that determine how testosterone behaves in your body: SHBG, CYP19A1, AR, SRD5A2, LHCGR, and CYP17A1. Part of 14 pathways and 150+ genetic insights, that map is the most actionable starting point available.

Man consulting a clinician on the genes that affect testosterone levels — PlexusDx Precision Peptide Genetic Test

What Genes Affect Testosterone Levels? The Complete Genetic Guide

The Precision Peptide Genetic Test analyzes six Reproductive Health genes that directly influence testosterone levels, conversion, and signaling — including SHBG, CYP19A1, AR, SRD5A2, LHCGR, and CYP17A1. Part of 14 pathways and 150+ genetic insights across 49 peptides, these variants explain why testosterone behaves differently in different men.

Man on TRT reviewing the genetic factors behind individual response — PlexusDx Precision Peptide Genetic Test

Why TRT Works for Some Men and Not Others: The Genetic Answer

The Precision Peptide Genetic Test analyzes 6 Reproductive Health insights that explain why androgen-pathway protocols produce different outcomes for different men. SHBG, CYP19A1, AR, SRD5A2, LHCGR, and CYP17A1 each shape how testosterone is bound, converted, sensed, and signaled — as part of 14 pathways and 150+ genetic insights across 49 peptides.

Male patient discussing DHEA and pregnenolone pathway genetics — PlexusDx Precision Peptide Genetic Test

DHEA and Pregnenolone Pathway Genetics: What Your DNA Reveals

The Precision Peptide Genetic Test analyzes CYP17A1 and related variants — the genes governing DHEA and pregnenolone synthesis in your adrenal androgen pathway. Part of 14 pathways and 150+ genetic insights across 49 peptides, your upstream steroid pathway genetics explain why the same hormonal support strategies produce different results across different men.