Wellness-focused adult representing the SIRT1 pathway, NAD+ signaling, and cellular repair — PlexusDx Precision Peptide Genetic Test

The SIRT1 Pathway: Genetics, NAD+, and Cellular Repair

SIRT1 is a NAD+-dependent enzyme that regulates DNA repair, inflammation, metabolic efficiency, and cellular stress response. Variants at rs12778366 and related loci influence how actively SIRT1 operates at baseline. The Precision Peptide Genetic Test analyzes SIRT1 as part of 17 Longevity & Aging insights spanning 14 pathways, 49 peptides, and 150+ genetic insights.

Active older adult representing the FOXO3 longevity gene — PlexusDx Precision Peptide Genetic Test results

The FOXO3 Longevity Gene: What Your Results Mean

FOXO3 is the most replicated longevity gene in science — variants are consistently associated with exceptional lifespan across independent centenarian cohorts in Japan, Italy, and the United States. The Precision Peptide Genetic Test analyzes FOXO3 as part of 17 Longevity & Aging insights within a panel spanning 14 pathways, 49 peptides, and 150+ genetic insights.