Vital older adult illustrating how the FOXO3 gene affects aging — PlexusDx Precision Peptide Genetic Test longevity panel

Does FOXO3 Affect How You Age? What the Science Shows

Yes — FOXO3 is one of the most replicated longevity genes in human genetics, and rs2802292 is the variant that explains why. The Precision Peptide Genetic Test analyzes FOXO3 alongside 14 pathways, 49 peptides, and 150+ genetic insights, revealing how your transcription factor genetics shapes oxidative stress resistance, DNA repair, and cellular lifespan.

Active older adult representing the FOXO3 longevity gene — PlexusDx Precision Peptide Genetic Test results

The FOXO3 Longevity Gene: What Your Results Mean

FOXO3 is the most replicated longevity gene in science — variants are consistently associated with exceptional lifespan across independent centenarian cohorts in Japan, Italy, and the United States. The Precision Peptide Genetic Test analyzes FOXO3 as part of 17 Longevity & Aging insights within a panel spanning 14 pathways, 49 peptides, and 150+ genetic insights.