Antioxidant capacity is not a single number — it is the combined genetic output of five overlapping enzyme systems, each with its own variant layer. The Precision Peptide Genetic Test maps SOD2, GPX1, GCLC, NFE2L2, FOXO3, and more across 14 pathways, 49 peptides, and 150+ genetic insights, revealing the genetic architecture your antioxidant biology is built on.

Glutathione synthesis, recycling, and detoxification capacity are all genetically variable — GCLC, GCLM, GSR, GPX1, GSTM1, and NFE2L2 each shape a different step. The Precision Peptide Genetic Test maps these variants across 14 pathways, 49 peptides, and 150+ genetic insights, revealing where your antioxidant production is genetically strongest and where it leaks.

SOD2 encodes the primary antioxidant enzyme inside your mitochondria — responsible for neutralizing reactive oxygen species at their source. The A16V variant (rs4880) determines how efficiently SOD2 is imported into the mitochondrial matrix. The Precision Peptide Genetic Test analyzes SOD2 as part of 17 Longevity & Aging insights spanning 14 pathways, 49 peptides, and 150+ genetic insights.

The PlexusDx Precision Peptide Genetic Test analyzes 17 longevity-aging genetic insights across five peptide pathways — Epitalon, FOXO4-DRI, Glutathione, Humanin, and Vilon — covering 15 SNPs across 14 genes including FOXO3, TERT, SIRT1, GPX1, and PPARGC1A. This article explains what each insight reveals and why peptide-specific longevity testing is a distinct category of genetic analysis.