HSA | FSA CARDS ARE NOW ACCEPTED

Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

Artery Hardening: How much do you know about the genetic origins of artery hardening which leads to atherosclerosis?

People often hold the belief that modern living habits alone cause this disease yet artery hardening has been present in human health since ancient times. We will examine the genetic elements which cause this widespread health problem to see how knowledge about your genetic predispositions enables you to manage your health effectively.

Understanding Artery Hardening:

Atherosclerosis refers to arterial stiffening caused by plaque accumulation which elevates the dangers of developing heart disease and stroke. Scientific studies of ancient mummies show that humans have experienced artery hardening throughout history while modern diets and sedentary lifestyles make the condition worse. The evidence indicates that genetic factors significantly influence how susceptible people are to developing this condition. The likelihood of developing artery hardening results from the interaction between genetic factors and lifestyle choices. Genetic variants in the EDNRA and EDNRB genes heighten the risk of developing atherosclerosis particularly among sedentary individuals. People can effectively reduce their genetic risk factors by customizing their lifestyle choices based on identified genetic predispositions. Genetic research indicates that genetic factors account for about 60% of individual susceptibility to atherosclerosis. Artery hardening develops because of risk factors like high blood pressure plus cholesterol levels and diabetes along with obesity smoking a sedentary lifestyle a poor diet and age. Your genetic risk score based on more than 50,000 genetic variants enables you to take informed steps to reduce overall risk through practical lifestyle changes.

Follow these practical guidelines to lower your risk of developing atherosclerosis or manage current conditions:

  1. Quit smoking to improve cardiovascular health.
  2. Choose a nutritious diet that includes numerous fruits, vegetables, and whole grains.
  3. Perform regular exercise to boost the health of your heart.
  4. Keep track of your blood pressure and cholesterol levels to maintain control over your health.
  5. Reach out to medical professionals to obtain tailored health advice that reflects your genetic makeup.

Conclusion:

Precision testing allows individuals to make smart health choices by understanding how their genetics influence artery hardening. The Precision Health & Wellness tests from PlexusDx accessible at PlexusDx.com along with Amazon and Walmart platforms enable you to discover your genetic vulnerabilities while providing tailored solutions to enhance your overall heart health. Take proactive steps now to ensure artery hardening does not control your health future.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

Real prescribers. Published prices. No surprises.

Licensed providers in all 50 states. Online intake. No insurance, no membership required.

Start My Intake →

~60 seconds · $0 charged until your provider approves