Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

Acne: Understanding the Role of Genetics in Acne Development

Acne affects people at different ages but remains the most common skin disorder among numerous individuals. The skin condition known as acne persists beyond teenage years into adult life where it damages self-esteem and reduces confidence. People often look for different skincare solutions to attain clear skin but they rarely understand how much their genetics influence acne development. Acne development susceptibility depends on genetic factors which play a substantial part in determining this process for individuals. Research shows genetic factors make up 50-90% of the variation in how likely people are to develop acne. An individual's genetic structure has a direct impact on their likelihood to experience acne breakouts. Scientists have analyzed over 31,000 genetic variants to provide individuals with the means to calculate their genetic risk scores for acne development. Personalized genetic analysis uncovers information about your unique genetic predispositions which influence acne development. With this information you can take active measures to combat acne triggers and sustain healthy skin. Certain genetic variations show a connection with the development of acne. OVOL1 and IL1A gene mutations lead to increased skin cell growth and inflammation which together trigger acne formation. By understanding genetic elements you can modify your skincare routine to attack the fundamental causes of acne instead of depending only on topical remedies.

Practical Tips for Managing Acne

  1. Dietary Adjustments: Research shows that acne development connects to sugary foods and dairy products hence you should reduce your intake of these dietary items.
  2. Stress Management: Practice mindfulness with yoga or meditation to minimize skin stress effects.
  3. Skincare Products: Select skincare products containing anti-inflammatory components like zinc and niacinamide to manage skin inflammation associated with acne.
  4. Genetic Testing: Undergo genetic testing to pinpoint your acne risk factors and develop a customized skincare routine with professional guidance. Use Precision Health & Wellness tests from PlexusDx to obtain accurate genetic predisposition data related to acne. Genetic testing helps individuals learn their genetic susceptibility to acne so they can make educated decisions about their skincare regimen and overall skin condition. Visit PlexusDx.com or search through Amazon and Walmart to discover how genetic testing influences acne treatment plans.

Acne develops as a multifaceted skin disorder that emerges through combined influences of genetic factors and environmental conditions with personal lifestyle choices. By learning about the genetic factors that contribute to your acne you can address its root causes and adapt your skincare regimen to suit your individual requirements. Acne treatment becomes successful when patients learn about what causes it and explore treatment possibilities. Start your journey towards clearer skin today with Precision Health & Wellness tests from PlexusDx for customized skin health management.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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