DHEA-S Blood Test

The DHEA-S Test measures dehydroepiandrosterone sulfate, an adrenal steroid and precursor to estrogen and testosterone. DHEA-S is linked to well-being, insulin sensitivity, bone and muscle support, cognition, skin health, and tends to peak in early adulthood before declining with age.

Why Measure DHEA-S?

  • Adrenal-androgen balance: Context for fatigue, low libido, mood changes, or hair/skin concerns.
  • Complement to cortisol: Helps frame stress physiology when reviewed with cortisol patterns.

Preparation & Consistency

Keep collection conditions similar across re-tests (time of day, medications). No routine fasting required.

How the PlexusDx Test Works

  • At-home finger-prick;
  • prepaid return mailer;
  • results in ~2 business days;
  • order direct; HSA/FSA accepted.

FAQ

Can stress change DHEA-S? Acute stress responses and aging both influence adrenal hormones; trends over time are most informative.