Use the Power of Genetics to Take Control of Your Methylation and Detox

With countless wellness options, finding what truly works for your body can be overwhelming. Precision Wellness Tests provide a personalized roadmap by analyzing how your unique genetics impact key health areas. These insights empower you to make informed decisions aligned with your goals—because health isn’t just about the genetic cards you’re dealt; it’s how you play them.

95+ DNA reports including MTHFR, COMT, BHMT, AHCY, Folate Metabolism and much more.

The PlexusDx Genetic Methylation Test offers a detailed look at the genetic factors that influence your body's detoxification and methylation process; essential for everything from cognitive health to hormone balance. By examining genes that impact nutrient absorption and environmental toxin clearance, this test provides a personalized food and detox strategy tailored to your unique genetic profile. It also delves into the methylation cycle, a critical biochemical process that regulates gene expression, produces antioxidants, and influences mental and physical well-being. By analyzing key genes like MTHFR, MTR, COMT, AHCY, and MTRR, this test identifies potential genetic bottlenecks in methylation that could impact areas such as cardiovascular health, mental wellness, and immune function. Armed with these insights and personalized recommendations, you'll be equipped to optimize your body's detox and methylation efficiency, supporting a balanced, resilient foundation for long-term health.

Your MTHFR + Methylation Comprehensive Genetic Test comes with evidence-based, actionable, and personalized supplement and meal plan recommendations including over 10,000 recipes.

  • WHAT YOU GET: 95+ personalized genetic reports and recommendations related to MTHFR, COMT, BHMT, Folate Metabolism, Detox, and much more
  • WHY PRECISION HEALTH? Precision Health tailors wellness solutions targeting areas like Cognitive Health, Hormone Balance, Detoxification, Antioxidants and more based on your unique DNA
  • HOW DOES IT WORK? Once you've opened your kit, register by following the instructions inside. Then, collect your sample and mail it back to us using the prepaid return mailer.
  • ACTIONABLE REPORTS: Practical reports for improving your overall wellness, including insights for PEMT, Vitamin B12, Riboflavin, Homocysteine, Supplements, Diet and Lifestyle Recommendations
  • TARGETED INSIGHTS: Tailor your diet, supplements, and lifestyle to your genetic makeup for optimal health and performance.
  • CUSTOM MEAL PLANS: Discover which foods and meal plans you should be eating based on your genetics. Identify optimal intake of macros, vitamins, and minerals. Includes over 10,000 recipes.
  • ADVANCED DNA TESTING: Get comprehensive reports with personalized diet, supplement, and lifestyle recommendations to achieve your health goals. Analysis of over 200 million genetic variants.
  • YOUR PRIVACY MATTERS: Your privacy is our priority. We use HIPAA compliant security and advanced encryption, ensuring your personal information is always protected.
  • One test for the rest of your life

    Personalized, actionable advice

    Achieve your health goals faster

    Lifestyle recommendations, backed by science

    Optimize your diet, macronutrients, vitamins and minerals

    Supplement advice based on 20,000 clinical studies

    Make Targeted Changes Based on Your DNA

    With personalized dietary, supplement, and lifestyle suggestions, you will understand why specific health recommendations are right for your body and tailored to meet your current health needs. Our recommendations are crafted based on your genetic profile because there is no such thing as one-size-fits-all.

    50 %
    of adults in the U.S. have at least one chronic health condition, many of which are impacted by genetic factors.1
    80 %
    of Americans have nutrient deficiencies, which can impact everything from cognitive function to immunity and metabolic health.2
    25 %
    of U.S. adults are affected by mental health conditions, where genetic predispositions play a key role in conditions such as anxiety, depression, and stress management.3

    How It Works

    Discover lifelong insights from one test.

    Order

    Select your test and purchase directly online. No doctor order required.

    Swab

    Follow the instructions included in your kit to ensure you collect an effective sample.

    Results

    Send your completed DNA specimen back and receive your personalized results.

    From Sofa to Science

    Experience the convenience of Precision Wellness right from your home. Just follow the simple steps included with your kit, and soon your detailed report will arrive at your doorstep.

    Your Kit Contains:

    1x INSTRUCTIONS & REGISTRATION CODE
    1x CHEEK SWAB & TRANSPORT TUBE
    1x BIOHAZARD BAG
    1x PREPAID RETURN MAILER

    Blog Posts

    View all

    Effects of COMT gene variant rs4680 on stress resilience and cognitive abilities?
    • 3 MIN READ

    Effects of COMT gene variant rs4680 on stress resilience and cognitive abilities?

    The COMT gene influences stress resilience and cognitive performance through enzyme activity variations (rs4680). Genetic testing can guide personalized wellness strategies for mental health optimization.
    What hardens arteries into atherosclerosis in the body?
    • 4 MIN READ

    What hardens arteries into atherosclerosis in the body?

    Genetic factors play a significant role in artery hardening (atherosclerosis) alongside lifestyle choices. Understanding genetic predispositions can help tailor preventive measures for better heart health.
    What genetic variations impact the absorption and effects of ginseng?
    • 4 MIN READ

    What genetic variations impact the absorption and effects of ginseng?

    PlexusDx offers personalized health reports on how genetics affect response to substances like ginseng. Genetic variants can impact ginseng absorption and efficacy, influencing benefits. Genetic testing and consultation can guide personalized supplementation for optimal results. Further research is needed to solidify evidence on genetic predispositions related to ginseng response.
    What are the genetic factors that increase susceptibility to strep infections?
    • 3 MIN READ

    What are the genetic factors that increase susceptibility to strep infections?

    Genetic makeup influences susceptibility to strep infections caused by Group A Streptococcus bacteria. Modifiable risk factors include hygiene, immune system strength, and avoiding crowded places. Seek medical attention for symptoms.
    What are the genetic factors linked to symptoms post-treatment in Chronic Lyme disease?
    • 5 MIN READ

    What are the genetic factors linked to symptoms post-treatment in Chronic Lyme disease?

    Genetics may influence Chronic Lyme symptoms. Certain genes affect immune response and toxin removal. Limited research calls for caution. Manage with healthcare guidance, self-care, and genetic testing for personalized care.
    What are the genetic factors affecting Irritable Bowel Syndrome (IBS)?
    • 4 MIN READ

    What are the genetic factors affecting Irritable Bowel Syndrome (IBS)?

    Genetics play a significant role in Irritable Bowel Syndrome (IBS). Understanding genetic factors can help tailor management strategies for symptoms, including lifestyle changes and personalized approaches. Consider genetic testing for personalized recommendations to improve quality of life with IBS.
    What are the genetic factors affecting IL-6 levels and health management?
    • 5 MIN READ

    What are the genetic factors affecting IL-6 levels and health management?

    IL-6 is a crucial cytokine in immune response, influenced by genetics and lifestyle. Balancing its levels is key for health, with tips like stress reduction and healthy habits.
    How do genetics affect creativity and how to enhance it?
    • 4 MIN READ

    How do genetics affect creativity and how to enhance it?

    Creativity is a genetic trait that influences how we approach situations with novel ideas. Genetics play a significant role, with about 20% of creativity attributed to genetic predispositions. Practical tips to enhance creativity include following passions, daydreaming, self-reflection, embracing novel experiences, and unconventional thinking.
    How do genetics affect Carnitine levels and how to optimize them?
    • 4 MIN READ

    How do genetics affect Carnitine levels and how to optimize them?

    PlexusDx provides insights on Carnitine, a key nutrient for energy production. Genetics influence Carnitine levels, impacting health. Tips include diet diversity, healthcare consultation, health monitoring, and genetic testing for personalized wellness optimization.