Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

Genital Herpes

The herpes simplex virus (HSV) causes genital herpes which represents a widespread sexually transmitted infection affecting many people. HSV-1 and HSV-2 transmission mainly occurs through skin-to-skin contact during sexual activities. Oral transmission is the primary mode for HSV-1 while HSV-2 is commonly known for causing genital herpes. Research indicates that 12% of both adolescents and adults carry HSV-2 but only some of them will actually develop genital herpes. The lack of a cure for HSV infections presents a significant difficulty because individuals can suffer repeated outbreaks which persist over long periods while they show no symptoms. Carriers of the virus pose a serious risk because they can spread the infection to others without knowing it themselves. The initial symptoms of genital herpes which develop days after infection include genital pain or itching with bumps or blisters appearing on genital and anal or oral areas besides painful urination and abnormal discharge and flu-like symptoms during the first outbreak. Genital herpes can lead to serious complications such as heightened risk for other STIs, newborn transmission during childbirth, reproductive organ inflammation, herpetic whitlow, and eye infections. The substantial effects of this infection make it essential to identify genetic aspects that affect susceptibility to genital herpes. People who have genetic predispositions show an increased probability of getting genital herpes. The risk of infection depends on variables including gender, ethnicity, sexual practices and other existing sexually transmitted infections (STIs). The populations at highest risk include women, African Americans, people who engage in diverse sexual behaviors, individuals who have multiple sexual partners, and people whose partners have active infections. The risk of developing genital herpes can be influenced by genetic differences which modify immune system reactions and cellular growth patterns alongside other biological functions. To lessen genital herpes risks individuals need to practice safe sex and attend regular health screenings. Using condoms consistently and reducing the number of sexual partners lowers transmission risks. Early infection detection through routine screenings leads to quick treatment and proper management. The study of genital herpes genetics reveals how genetic factors contribute to the intricate relationship between heredity and infectious diseases. Understanding which genetic factors lead to susceptibility allows people to take active precautions to safeguard both themselves and their partners. The Precision Health & Wellness tests from PlexusDx present valuable information for those who wish to learn more about their genetic risks for disease and infection. Utilize genetic information to guide your health decisions which will lead to improved well-being.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.