Last reviewed: May 12, 2026 Last updated: May 12, 2026

Written by: Jay Hastings , CEO of PlexusDx

Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations. He has more than 20 years of experience across healthcare innovation, genomics, laboratory operations, healthcare investing, and strategic finance. His work has included scaling healthcare startups, leading CLIA lab integrations, and helping expand consumer access to precision health tools.

Medically reviewed by: Jayden Lee, PharmD, EMBA

Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes. Dr. Lee has more than 10 years of professional experience in clinical pharmacy, academia, and research.

Rapid Growth and Stretch Marks: Understanding the Genetic Basis

Rapid growth or bodily changes frequently cause stretch marks which represent a widespread skin issue affecting numerous people. While these narrow bands of colored skin cause worry for many people who experience them understanding the genetic basis of stretch marks gives important knowledge about how to prevent them and manage their appearance. This blog post examines stretch marks as a genetic trait and explains both the primary causes of their development and ways people can actively manage them.

Stretch marks or striae develop when the skin stretches or shrinks too quickly causing the proteins collagen and elastin to rupture and form scars. The scar tissue that develops through skin stretching creates distinctive bands which show up as pink, purple, or brown based on the person's skin color. Stretch marks commonly develop across different body regions but occur more frequently in situations involving quick bodily growth or substantial changes including pregnancy and weight shifts.

Studies of genetics have elucidated how different gene variants contribute to stretch mark formation by affecting elastin and other skin proteins. An individual's risk of developing stretch marks increases if they identify as female or experience pregnancy along with rapid growth or weight changes and if they use steroids or undergo breast enlargement surgery while having African ancestry. Research has mapped various gene variants that play a role in stretch mark development and revealed the genetic basis of this skin issue. Although the scientific evidence supporting the genetic model of stretch marks remains weak currently researchers can still give useful information to people who want to prevent or manage stretch marks by understanding genetic predispositions.

Individuals who understand their genetic risk factors for stretch marks can actively manage risk factors they can change to lower their chances of getting stretch marks. People who worry about stretch marks or possess a genetic predisposition can take specific measures to reduce their risk. We present practical recommendations to guide you through effective stretch mark management.

  1. Maintain a Healthy Lifestyle: Maintaining skin health through proper nutrition and exercise routines alongside sufficient water intake helps boost skin elasticity and prevents stretch marks from forming.
  2. Manage Weight Changes: A slow and sustainable approach to weight management reduces skin strain and protects against stretch marks caused by quick weight fluctuations.
  3. Use Skincare Products: The application of moisturizers and creams that improve skin hydration and elasticity helps reduce the visibility of current stretch marks while stopping new marks from appearing.
  4. Consult a Healthcare Provider: Seek professional medical guidance from a healthcare provider or dermatologist if you need personalized treatment options for your stretch marks.

Knowledge of genetic contributors to stretch marks allows individuals to actively manage this frequent skin issue. Individuals can decrease their chances of developing stretch marks while enhancing their skin health by controlling risk factors they can modify and practicing healthy habits and seeking expert advice when necessary. The Precision Health & Wellness tests offered by PlexusDx allow individuals to understand their genetic predispositions and potential risk factors for stretch marks through their platform at PlexusDx.com or through Amazon and Walmart. Start managing your skin health immediately through knowledgeable choices that enhance your overall well-being.

Medical and Editorial Standards

Medical review process: This article was reviewed for medical accuracy, scientific clarity, evidence alignment, and appropriate discussion of genetics, medications, supplements, biomarkers, and health-related claims.

Sources and evidence: PlexusDx educational content is developed using peer-reviewed research, clinical literature, reputable medical references, and, where applicable, public health or regulatory guidance. References are included at the end of the article when scientific, medical, or health-related claims are discussed.

Commercial transparency: PlexusDx offers genetic testing, blood biomarker testing, personalized supplement recommendations, and related precision wellness services. Product mentions are intended to help readers understand available options and should not be interpreted as medical advice.

Important disclaimer: PlexusDx educational content is for informational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making decisions about medications, supplements, genetic testing, lab testing, or health-related care.

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